amali 3 ( antatomi dan fosiologi)

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    Lab Activity 5

    The Integumentary System

    Martini Chapter 5

    Institut Pendidikan Guru Malaysia

    PJM3106

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    Skin

    Epidermis: Superficial layer

    Made of stratified squamous keratinized epithelium

    4-5 Layers

    Dermis: Underlying connective tissue layer

    2 Layers

    Hypodermis: Not part of the skin, it is deep to

    the dermis

    Primarily adipose tissue

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    Layers of the Epidermis

    1. Stratum corneum: Outermost layer

    20-30 cell layers thick

    Cells are dead and flattened

    Full of keratin

    Constantly being rubbed off

    2. Stratum lucidum: Thin translucent layer of

    dead keratinocytes

    Found only in thick skin

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    Layers of the Epidermis

    3. Stratum granulosum: Cells contain granules

    The upper part of this layer has cells that are

    beginning to die

    Lamellated granules contain a waterproofing

    glycolipid that is secreted into the extracellular

    space Keratohyaline granules combine with intermediate

    filaments to form keratin fibrils

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    Layers of the Epidermis

    4. Str atum spinosum: several cell layers

    Cells also dividing

    Cells contain bundles of intermediate filaments

    made of pre-keratin

    5. Stratum basale:single row of cells

    Adjacent to the dermis

    Constantly dividing and pushing up layers

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    Dermis

    The dermis is the connective tissue layer under the

    epidermis

    1. Papillary Layer:Superficial dermal region Areolar connective tissue

    Contains capillaries, lymphatics and sensory neurons

    Dermal Papillae: the fingerlike projections from the

    superior surface

    Epidermal ridge:The epidermal layer that dips down into

    the dermal papillae

    Create fingerprints

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    Dermal Papillae

    Epidermal ridge

    Papillary

    Layer

    Reticular

    Layer

    Epidermis

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    Finger Prints

    Epidermal

    Ridge

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    Dermis

    2. Reticular Layer: Deepest skinlayer

    Dense irregular connective

    tissue Contains the arteries, veins,

    sweat and sebaceous glands

    Cleavage lines: the deep

    creases (like in the palm)where collagen and elasticfibers are arranged in

    parallel bundles.

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    Cleavage Lines

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    Hypodermis

    Subcutaneous layerthat is not part of theskin

    Beneath the dermislayer

    Composed of adiposeand areolar connectivetissue

    Highly vascular

    Dermis

    Hypodermis

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    Cells of the Epidermis

    Keratinocytes: The main cells of the epidermis

    Produce keratin, a fibrous protein that gives skin its

    durability and protective capabilities

    Melanocytes: Spidery black cells

    In stratum basale

    Produce melanin, the pigment that protects skinfrom UV damage

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    Cells of the Epidermis

    Langerhans Cells: Also called epidermal

    dendritic cells

    In stratum spinosum

    Macrophages that migrated from the bone marrow

    that phagocytize pathogens

    Immunologic surveillance cells

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    Cells of the Epidermis

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    Hair

    Root:

    Everything that

    is not sticking

    out of the skin

    Shaft: The part

    sticking out of

    the skin Bulb:Active

    growing site

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    Hair Histology

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    Arrector Pili Muscle

    Arrector pili muscle: Smooth muscle that pull hair

    upright during fright or cold (goose bumps)

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    Apocrine Sweat Glands

    Apocrine glands: secrete a

    protein and fat rich substance

    that bacteria can use for

    nutrients (creates body odor) Found in the armpits, around

    nipples and in the pubic region

    Secrete products into hairfollicles or directly onto the

    surface.

    Begin functioning at puberty

    A i

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    Apocrine

    Sweat Glands

    Red arrow-

    Apocrine Sweat

    Glands

    Green arrow-

    Hair follicle

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    Eccrine (Merocrine) Sweat Glands

    Eccrine sweat glands

    are not associated with

    hair follicles.

    Ducts open directly on

    the surface of the

    epidermis

    S b

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    Sebaceous

    Glands

    Sebaceous glands

    Produce oily

    substance calledsebum

    Helps waterproof

    the skin

    Acne:infection of the

    sebaceous gland

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    Sebaceous Follicle

    Sebaceous glands notassociated with hairfollicles

    Secrete their productdirectly on the skinsurface

    Located on face, back,chest, nipples andexternal genitalia

    P i i (L ll t d)

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    Pancinian (Lamellated)

    Corpuscle

    Lie deep in the dermis

    Respond only when deep pressure is first applied

    Monitor high frequency vibrations

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    Meissners (Tactile) Corpuscle

    Located in the dermal papillae

    Receptor for light touch

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    Merkel Cells

    Merkel Cells: At the junction of the sensory

    nerve endings

    In stratum basale

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    Fingernails

    Scale like modification of the epidermis

    Free edge: part that grows away from the finger

    Body: visible attached portion Root:Embedded in skin and sticks to the nail bed

    Nail Bed: Extension of the stratum basale beneath thenail

    Nail Matrix: Proximal part of the nail bed responsiblefor nail growth

    Lunula: white crescent area; Most active growth regionof nail matrix

    Fi il

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    Fingernail

    Structures

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    Lab Activity 6

    Body Membranes

    Martini Chapter 4, Pages 129-131

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    Body Membranes

    The majority of the bodys structures are lined

    by epithelial membranes

    An epithelial membraneis a continuous

    multicellular sheet composed of epithelium

    bound to an underlying layer of connective

    tissue.

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    Epithelial Membranes

    Cutaneous: skin

    Mucous:lines body

    cavities open to theexterior(e.g., digestive andrespiratory tracts)

    Serous: moistmembranes found inclosed ventral bodycavity (mesothelium) forreducing friction

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    Epithelial Membranes: Serous

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    Mucous Membrane

    Line all body cavities open to the exterior

    Epithelial cells resting on a lamina propria(loose connective tissue)

    Goblet cells: columnar epithelial cells with largemucus containing vacuoles

    Usually secrete mucous, but not always

    Respiratory tract GI tract

    Urinary tracts

    Genital tracts

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    Mucous Membrane

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    Serous Membranes

    Line all body cavities closed to the exterior and

    the internal surface of the organs

    Simple squamous epithelium with small amountof areolar connective tissue

    Is double layered

    Parietal layer covers the cavity Visceral layer covers the organs

    There is serous fluid between the layers to reduce

    friction when they slide against each other

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    Serous Membranes

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    Parietal Layer

    Special name depending on the organ it is

    associated with

    Parietal peritoneum: covers abdominal wall

    Parietal pleura: covers chest cavity

    Parietal pericardium: outside layer of sac

    surrounding the heart

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    Pericardial Membranes

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    Pleural Membranes

    Peritoneal

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    Peritoneal

    Membranes

    Parietalperitoneum is the

    blue line Visceral

    peritoneum is thepink lines

    Peritoneal cavityis the gray

    Synovial

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    Synovial

    Membranes

    Composed entirely

    of connective tissue

    Line cavities of

    joints

    Secrete synovial

    fluid for lubrication

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    The End