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Abstract Workshop on Atmospheric Chemistry and Climate Change in Asia 2014 (WACCCA2014) Exposure Assessment and Biological Monitoring Of Volatile Organic Compunds (VOCS) in Exposed Workers in Manufacturing Industry In Selangor Norshazira Umran 1 , Mazrura Sahani 1 , Mokhtar Sabtu 2 , Norhayati Mohd Tahir 3 1 Pusat Pengajian Sains Diagnostik dan Kesihatan Gunaan, Fakulti Sains Kesihatan, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur 2 Jabatan Kesihatan dan Keselamatan Pekerjaan Negeri Selangor, Tingkat 7, Wisma Consplant2, Jalan SS16/1, 47500 Subang Jaya, Selangor 3 Fakulti Sains dan Teknologi, Universiti Malaysia Terengganu, 21030 Kuala Terengganu, Terengganu, ABSTRACT Volatile organic compounds (VOCs) exposure can induce a range of adverse human health effect. A risk assessment of hazardous indoor air pollutant exposure to workers’ health using biomonitoring of the workers in manufacturing industry in Selangor was conducted. This cross sectional study will be focussed on assessment of exposure to the indoor air environment and estimation of health risk to the occupationally exposed workers using biomarkers of exposure. A total of 56 workers from the operation and administration department in manufacturing industry in Selangor were recruited as the high exposed and low exposed group respectively. A survey using a standardized questionnaire was carried out among these workers. For the assessment of exposure to workers, indoor air sampling; area and personal were conducted. For workers biomonitoring, survey among workers and collection of their biological samples (urine sample) was carried out. Sampling has been done and the indoor air parameters that will be determined are n-hexane, trichloroethylene and benzene. Biomarker of exposure for n-hexane, trichloroethylene and benzene will be determine in urinary 2,5-hexanedione, trichloroacetic acid and S-phenylmercapturic acid respectively.The outcome of the study will be used to update the existing guideline on medical surveillance under USECHH 2000. This study will contribute to the establish the biomarkers of exposure to the selected VOCs among the workers.

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Page 1: Exposure Assessment and Biological Monitoring Of · PDF fileExposure Assessment and Biological Monitoring Of Volatile Organic Compunds ... the existing guideline on medical surveillance

Abstract Workshop on Atmospheric Chemistry and Climate Change in Asia 2014 (WACCCA2014)

Exposure Assessment and Biological Monitoring Of Volatile Organic Compunds (VOCS) in Exposed Workers in Manufacturing Industry In Selangor Norshazira Umran1, Mazrura Sahani1, Mokhtar Sabtu2, Norhayati Mohd Tahir3 1Pusat Pengajian Sains Diagnostik dan Kesihatan Gunaan, Fakulti Sains Kesihatan, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur 2Jabatan Kesihatan dan Keselamatan Pekerjaan Negeri Selangor, Tingkat 7, Wisma Consplant2, Jalan SS16/1, 47500 Subang Jaya, Selangor 3Fakulti Sains dan Teknologi, Universiti Malaysia Terengganu, 21030 Kuala Terengganu, Terengganu,

ABSTRACT Volatile organic compounds (VOCs) exposure can induce a range of adverse human health

effect. A risk assessment of hazardous indoor air pollutant exposure to workers’ health using

biomonitoring of the workers in manufacturing industry in Selangor was conducted. This cross

sectional study will be focussed on assessment of exposure to the indoor air environment and

estimation of health risk to the occupationally exposed workers using biomarkers of exposure. A

total of 56 workers from the operation and administration department in manufacturing

industry in Selangor were recruited as the high exposed and low exposed group respectively. A

survey using a standardized questionnaire was carried out among these workers. For the

assessment of exposure to workers, indoor air sampling; area and personal were conducted. For

workers biomonitoring, survey among workers and collection of their biological samples (urine

sample) was carried out. Sampling has been done and the indoor air parameters that will be

determined are n-hexane, trichloroethylene and benzene. Biomarker of exposure for n-hexane,

trichloroethylene and benzene will be determine in urinary 2,5-hexanedione, trichloroacetic

acid and S-phenylmercapturic acid respectively.The outcome of the study will be used to update

the existing guideline on medical surveillance under USECHH 2000. This study will contribute to

the establish the biomarkers of exposure to the selected VOCs among the workers.