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    RAWATAN KLIEN DUA DIAGNOSIS

    (PSIKIATRIK SEMASA DETOKSIFIKASI)

    DR OMAR ALIPakar Perunding Psikiatri

    Hospital Sultanah Bahiyah

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    What is Dual Diagnosis?

    Dual diagnosis exists where

    alcohol or drug problem and

    an emotional/another mental

    health(psychiatric) problem

    Also known as Co-morbidity

    Co-occuring disorders

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    Substance Abuse and Mental

    Illness

    A dual diagnosis orco-occurring disorder occurs when an

    individual is affected by both chemical dependency and mental

    illness.

    Both illnesses may affect a person physically, socially,

    psychologically, and spiritually. Each illness has symptoms thatinterfere with a persons ability to function effectively.

    The illnesses may affect each other, and each disorder

    predisposes to relapse in the other disease. At times the

    symptoms can overlap and even mask as each other, makingtreatment and diagnosis difficult.

    To fully recover, a person needs to treat/address both disorders.

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    How Common Is Dual Diagnosis?

    37% of people abusing alcohol53% people abusing other drugs

    Have at least one serious mental illness.

    29% of people diagnosed as mentally ill,

    abuse either alcohol or drugs.American Medical Association

    74% of users of drug services

    85% of users of alcohol services

    experienced mental health problems.

    44% of mental health service users reported drug use.

    UK Dept. of Health

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    Sains Malaysiana 42(3)(2013): 417421

    Psychiatric Comorbidity Among Community-based, Treatment

    Seeking Opioid Dependents in Klang Valley

    (Komorbiditi Penyakit Psikiatri dalam Kalangan Penagih yang

    Bergantung pada Opioid di Lembah Kelang)

    AzLin BAhAruDin*, LOTfi AnuAr, SuriATi SAini, OSMAn Che BAKAr,

    rOSDinOM rAzALi & niK ruzyAnei niK JAAfAr

    204 penagih

    43.6% daripada kumpulan penagih opioid inimempunyai komorbiditi psikiatri. Penyakit Kemurungan 32.6%,

    penyakit disthiamia pada 23.6%

    penyakit Panik pada 14.6%.

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    Sains Malaysiana 42(3)(2013): 417421

    Psychiatric Comorbidity Among Community-based, Treatment

    Seeking Opioid Dependents in Klang Valley

    (Komorbiditi Penyakit Psikiatri dalam Kalangan Penagih yang

    Bergantung pada Opioid di Lembah Kelang)

    AzLin BAhAruDin*, LOTfi AnuAr, SuriATi SAini, OSMAn Che BAKAr,

    rOSDinOM rAzALi & niK ruzyAnei niK JAAfAr

    Komorbiditi psikiatri didapati mempunyai perbezaan siknifikan (p

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    So what?

    Must be dry to access most addiction rehab

    services

    Cant get dry because of mental health issue

    e.g. anxiety-self medicate e.g. drink to reduce

    anxiety

    Addiction Treatment centres dont assess for

    other mental health problems

    Reduces chances of long term recovery

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    Contoh Client / Pesakit

    DIN

    Zahari

    Nizam

    See Leng

    Zul

    Mr x

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    Why is dual diagnosis a problem?

    Historically addiction seen as Moral issue

    Form of mania

    Disease

    Addiction and mental health services separate AA/rehab centres: bias against medication

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    Dual Diagnosis Problems

    76% of services failing to offer a specificservice for people with dual diagnosis

    Dual Diagnosis not clearly understood or

    formally recognised Service models used aligned to organisations

    rather than complex needs of people with

    dual diagnosisMental health & addiction services and the management of dual

    diagnosis in Ireland National Advisory Committee on Drugs 2004.

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    Diagnosis #1:

    MENTAL ILLNESS

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    What is Mental Illness:

    Mental Illness Facts

    Mental illnesses are medical conditions that

    disrupt a persons thinking, feeling, mood, ability

    to relate to others, and daily functioning. Just as

    diabetes is a disorder of the pancreas, mental

    illnesses are medical conditions that often result

    in a diminished capacity for coping with the

    ordinary demands of life.

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    Serious mental illnesses

    Include:

    major depression

    schizophrenia

    bipolar disorder

    obsessive compulsive disorder (OCD)

    panic disorder

    post traumatic stress disorder (PTSD)

    borderline personality disorder

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    In Addition to Medication Treatment

    Psychosocial treatment such as cognitive behavioral therapy,

    interpersonal therapy,

    peer support groups,

    and other community services can also be components ofa treatment plan that assist with recovery.

    The availability of transportation, diet, exercise, sleep,friends, and meaningful paid or volunteer activitiescontribute to overall health and wellness, includingmental illness recovery.

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    Diagnosis Specific Signs and

    Symptoms

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    Major Depression

    Dysphoric mood

    At least 4 of the following

    Changes in appetite and sleep patterns, agitation, loss

    of interest in pleasurable activities, fatigue,worthlessness, guilt, inability to concentrate,

    ruminating negative thoughts, feeling helpless and

    hopeless, recurrent thoughts of death

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    Signs and Symptoms of Depression

    Tearful

    Changes in sleeping patterns

    suicidal ideation

    changes in appetite loss of pleasure

    isolation

    sudden outburst of anger

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    Difficulty concentrating

    Ruminating thoughts

    Feeling helpless

    Feeling hopeless

    Feeling like life is not worth living

    Ruminating on negative thoughts

    Emotional numbness

    Signs and Symptoms of Depression

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    Bipolar Disorder

    Bipolar disorder, also known as manic depression, is a brain

    disorder that causes unusual shifts in a person's mood, energy, and

    ability to function. Different from the normal ups and downs that

    everyone goes through, the symptoms of bipolar disorder aresevere. They can result in damaged relationships, poor job or school

    performance and even suicide.

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    Bipolar Disorder: Manic

    One of more distinct period with a predominantly elevate,

    expansive or irritable mood

    Duration of at least one week during which most of the time at

    least 3 have been present

    Increase in activity, hyper verbal or pressured speech, flights ofideas, grandiosity, decreased need for help, distractibility,

    buying sprees, sexual indiscretions, foolish business

    investments, reckless driving

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    Personality Disorders

    Each of us has a personality or group of characteristics(traits) which influence the way we think, feel & behave and

    makes us a unique individual.

    Someone may be described as having a 'personality disorder'

    if their personal characteristics cause regular and long termproblems in the way they cope with life and interact with

    other people. Some people with these disorders never come

    into contact with the mental health services.

    APA: when personality traits are inflexible and maladaptive

    and cause either significant impairment in social oroccupational functioning or subjective distress.

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    Personality Disorders

    Approximately 10-13% of the population have

    a personality disorder. Personality disorders

    are more common in younger age groups(25-44 year age group) and are equally

    distributed between males and females.

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    Personality Disorders

    Prominent characteristics

    Tx of problematic relationships

    Blames difficulties on others or bad fortune

    Doesnt learn from mistakes Generate and perpetuate existing problems

    Lack of control over emotions

    Distorted thinking

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    Types of Personality Disorders

    Divided into 3 Clusters:

    A) odd/eccentric : paranoid, schizoid

    B) dramatic/erratic: antisocial, borderline,histrionic, narcissistic

    C) anxious/inhibited: dependent, avoidant,

    obsessive-compulsive

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    Antisocial Personality Disorder

    Current age of at least 18

    Onset before 15 as indicated by 3 or more:

    Truancy, expulsion, delinquency, running away

    from home, arrested, persistent lying, repeated

    sexual intercourse, repeated drunkenness or

    substance abuse, thefts, vandalism, low school

    grades, chronic violations of home rules, initiationof fights

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    Antisocial Personality Disorder

    At least 4 of the following since age 18:

    Inability to sustain consistent work behavior

    Lack of ability to function as a responsible parent

    Failure to accept social norms with respect to lawful

    behavior

    Inability to maintain enduring attachment to a sexual

    partner

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    Antisocial Personality Disorder

    Irritability and aggressiveness

    Failure to honor financial obligations

    Failure to plan ahead or impulsivity

    Disregard for the truth

    Recklessness

    A pattern of continuous antisocial behavior in which

    the rights of others are violated

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    Borderline Personality Disorder

    At least 5 of the following:

    Impulsivity or unpredictability in at least 2 areas that are

    potentially self damaging-Spending, sex, gambling, shoplifting,

    AOD use, etc

    A pattern of unstable and intense interpersonal relationships

    Inappropriate, intense anger or lack of control over anger

    Identity disturbances

    Affective instability

    Intolerance of being alone

    Physical self damaging acts

    Chronic feelings of emptiness and boredom

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    The Good News About Mental Illness:

    Is that recovery is possible.

    Mental illnesses can affect persons of any age, race, religion, or

    income.

    Mental illnesses are not the result of personal weakness, lack ofcharacter, or poor upbringing.

    Most people diagnosed with a serious mental illness can

    experience relief from their symptoms by actively participating

    in an individual treatment plan.

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    Diagnosis #2:

    SUBSTANCE ABUSE

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    Addiction = A Dog with a Bone

    It never wants to let go.

    It bugs you until it gets

    what you want.

    It never forgets

    when/where it is used to

    getting its bone.

    It thinks its going to get abone anytime I do anything

    that reminds it of the bone.

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    Substance Abuse and Mental Illness

    = Co-Occurring Disorder

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    Co-Occurring Risk Factors

    Childhood risk factors such as poverty, family discord, and pre

    and postnatal complications appear to be implicated in both

    mental illness and substance use.

    Between 51 and 97 percent of women with serious mental

    illness have been physically or sexually abused.

    41 to 71 percent of women treated for alcohol or drug use report

    being sexually abused.

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    Stigmas

    Alcohol and drug abuse have many negative

    connotations in our society. For many, drug

    abuse is perceived to result from lack of

    willpower, laziness, or selfishness. Sadly, theseerroneous perceptions also extend to a group

    extremely vulnerable to drug abuse people with

    mental disorders.

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    Relationship between Substance

    Abuse and Mental Illness

    Those with a mental disorder can be very sensitive tothe effects of drug abuse; not only can it be easier toabuse drugs, it can also be harder to quit.

    Like the rest of the population, a person with a mental

    disorder is more likely to abuse drugs if there is afamily history of alcohol and drug abuse.

    Environmental factors such as peer pressure,location, and the availability of the drug alsocontribute to a pattern of drug abuse in the mentallyill.

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    Relationship between Substance

    Abuse and Mental Illness, cont.

    Drug use can interfere with prescribed medication,

    increase symptoms of a mental condition, and

    increase relapse risk.

    Having difficulty developing social relationships,some people find themselves more easily accepted by

    groups whose social activity is based on drug use.

    Some believe that an identity based on drug

    addiction/alcoholism is more acceptable than one

    based on mental illness.

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    Theories of Dual-Diagnosis

    Self-medication theory: Substances are selectivelyused in service of alleviating symptoms of mentalillness (i.e. stimulant abuse employed to counter thesedative effects of anti-psychotic medications)

    Alleviation of dysphoria: mental illness creates

    dysphoria (feeling bad) and this dysphoria leads todrug use to mitigate the experience of theseunpleasant feelings

    Multiple risk: In addition to the alleviation of bad-feelings, there are additional risks such as: social

    isolation, poverty, lack of daily structure, residing inareas with drug availability, history of traumaticevents

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    Some Key Factors

    Studies in the UK and United States haveindicated that individuals with dual-diagnosishave a number of difficulties and poorer

    outcomes including: Increased severity of symptoms and relapse

    More frequent inpatient hospital admissions

    Higher treatment costs Increased hostility and involvement with the

    legal system

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    Key Factors Continued

    Increase likelihood of suicide

    Increased rate of homelessness and insecure

    housing

    Increased risk of HIV infection

    Family problems or intimate relationships

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    Ciri-ciri Relapse

    Rasmussen (2000) ada menggariskan ciri-ciri relapse ialah perubahan dalaman individu seperi

    peningkatan stress,

    perubahan pemikiran,perasaan dan tingkah laku;menafikan tentang rasa kebimbangan yang dialami;

    menghindari dan mempertahan diri sendiri bahawa tidak relapse sebaliknya memfokuskan kepada oranglain,

    bersifat defensive,

    bersifat kompulsif,berkelakuan impulsive

    krisis lanjutan seperti melihat remeh sesuatu masalah,perasaan yang tertekan, perancangan masa hadapan yang lemah dan gagal;

    berfikiran bahawa semua perkara tidak dapat diselesaikan

    bertindak secara tidak matang untuk tujuan bergenbira atau berseronok.Individu juga berasa keliru dan memberi reaksi yang berlebihan kesan daripada tidak dapat berfikir dengan

    jelas, tidak dapat mengurus perasaan dan emosi ,

    sukar untuk mengingati sesuatu,berasa keliru.

    tidak dapat mengawal stres dan menjadi mudah marah.

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    Ciri-ciri Relapse

    kemurungan (depression) tabiat makan yang luar biasa (tidak lalu atau terlalu banyak makan),

    kurang bersemangat untuk mengambil sesuatu tindakan,

    sukar untuk tidur,

    terjejas aktiviti harian

    mengalamisuatu tempoh tekanan yang agak lama.

    Individu yang relapse juga akan kehilangan kawalan kerana memendam perasaan, berasa tidak mampu dan tidak berguna,

    menolak pertolongan,

    melanggari program pemulihan,melanggar nilai nilai diri,

    hilang keyakinan diri,marah tanpa sebab,suka bersendirian,kecewa

    mengalami tekanan.

    Ciri-ciri terakhir ialah individu mula relapse dengan mengambil dadah akibatnya berperasaankecewa,hilang kawalan diri dan kehidupan serta kemerosotan tahap kesihatan.

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    PENCEGAHAN DADAH MELALUI RAWATAN

    Pendekatan farmakologiPendekatan farmakologi bergantung kepada ubat-ubatan atau dadahuntuk menyekat kesan euforik, ataupun mengurangkan kegianan sertaslmptom putus dadah (withdrawl symptoms) semasa dadah digunakan

    methadone, -

    Naltrexone,

    buprenorphine,

    ubat-ubatan juga digunakan dalam proses detoksifikasi dengan tujuan untukmengawal kegianan.

    dadah digunakan bagi mengurangkan masalah dual-diagnosis sepertikemurungan atau skizofrenia.

    prevalen salah guna bahan dalam kalangan kes mental seperti inimencapai 50 peratus.

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    The Four Quadrant Model

    The Four Quadrant Model is a viable mechanism

    for categorizing individuals with co-occurring

    disorders for the purpose of service planning

    and system responsibility.

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    Sub-Groups of Dual Diagnosis Client

    Types

    Psychiatric High

    Substance High

    Serious & persistent mental illnesswith substance dependence

    Psychiatric Low

    Substance High

    Substance dependence with somepsychiatric complications

    Psychiatric High

    Substance Low

    Serious and persistent mental

    illness with substance abuse

    Psychiatric Low

    Substance Low

    Mild psychopathology with

    substance abuse

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    Treatment Continued

    Parallel: These intervention approaches focus on bothsubstance abuse and mental illness treatment at thesame time

    Integrated: Treatments are delivered at the same time

    (like the parallel approach) but are coordinated by thesame staff team members in the same treatmentsetting

    Specific approaches with in these 3 philosophies include:

    Biological: This is the psychotropic medication arm oftreatment and can be effective toward managingsymptoms of mental illness which in turn can facilitatetreatment of substance misuse

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    Treatment Continued

    Social and Psychological: This is a broad spectrumterm used to describe therapeutic techniques suchas:

    Motivational Interviewing: Engaging in supportiveand directed conversation about individualsbehaviors and patterns that are designed to increaseintrinsic motivation to change

    Cognitive Behavioral: weakening connectionsbetween life stressors and reactive/habitualresponses that are negative and destructive.

    Self-Help Groups: This includes many 12-step groupsthat can instill peer support and self-discipline

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    AOS Programs

    Programs that offer Addiction-Only Services

    Some addiction treatment programs cannot accommodate

    patients with psychiatric illnesses that require ongoing

    treatment, however stable the illness and however wellfunctioning the individual. Such programs are said to provide

    Addiction-Only Services

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    DDC Programs

    Dual Diagnosis Capable (DDC) Programs

    Dual Diagnosis Capable (DDC) programs routinely accept

    individuals who have co-occurring mental and substance-

    related disorders. DDC programs can meet such patients needsso long as their psychiatric disorders are sufficiently stabilized

    and the individuals are capable of independent functioning to

    such a degree that their mental disorders do not interfere with

    participation in addiction treatment.

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    DDE Programs

    Dual Diagnosis Enhanced (DDE) Programs

    DDE programs can accommodate individuals with dual

    diagnoses who may be unstable or disabled to such an extent

    that specific psychiatric and mental health support. monitoring

    and accommodation are necessary in order for the individual to

    participate in addiction treatment. Such patients are not so

    acute or impaired as to present a severe danger to self or

    others, nor do they require 24-hour, intensive psychiatric

    supervision.

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    The ideal

    Client & professionals can see and access holistic service

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    The reality

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    Strategies forPsychopharmacology with

    Persons who have

    Co-Occurring Disorders

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    PSYCHOPHARMACOLOGY PRACTICE

    GUIDELINES

    DUAL PRIMARY TREATMENT

    ADDICTION PSYCHOPHARM

    Disulfiram

    Naltrexone

    Acamprosate

    Bupropion, Varenicline

    Opiate Maintenance

    Mood stabilizers?

    Others? (Baclofen, etc.)

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    PSYCHOPHARMACOLOGY PRACTICE

    GUIDELINES

    DUAL PRIMARY TREATMENT

    PSYCHOPHARM FOR MI

    Atypicals (?) and clozapine for psychosis

    LiCO3 vs newer generation mood stabilizers

    Any non-tricyclic antidepressant, particularly

    SSRI, SNRI

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    PSYCHOPHARMACOLOGY PRACTICE

    GUIDELINES

    DUAL PRIMARY TREATMENT PSYCHOPHARM FOR MI

    Anxiolytics: clonidine, SSRIs, SNRIs, topiramate,other mood stabilizers, atypicals (short-term),

    ADHD: Atomoxetine is probably first line.Bupropion, clonidine, SSRIs, tricyclics, then

    sustained release stimulants.

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    SAFETY Acute medical detoxification should follow same

    established protocols as for individuals with

    addiction only.

    Maintain reasonable non-addictive psychotropicsduring detoxification

    For acute behavioral stabilization, use whatever

    medications are necessary (including

    benzodiazepines) to prevent harm.

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    APAKAH PRINSIP ASAS RAWATAN PENAGIHAN DADAH YANG BERKESAN? Prinsip asas rawatan penagihan dadah yang berkesan adalah:

    1. Tiada rawatan tunggal sesuai untuk semua individu klien.2. Rawatan dan pemulihan perlulah mengikut keperluan klien yang unik.3. Kemudahan rawatan perlu sentiasa ada (tersedia).4. Rancangan pemulihan perlu dinilai dan dikaji semula dari masa ke masa.

    5. Klien hendaklah berada dalam tempoh rawatan yang mencukupi.6. Kaunseling dan terapi tingkahlaku merupakan komponen yang kritikaldan berkesan dalam rawatan.7. Ubat-ubatan boleh membantu rawatan penagih dadah.

    8. Dual-diagnosis perlu untuk penagih bermasalahpsikiatri.9. Detoksifikasi penting untuk menghilangkan kegianan.10. Motivasi dalaman dan luaran boleh membantu pemulihan.11. Status kepulihan klien perlu dipantau.12. Pengesanan HIV dan penyakit kronik perlu dibuat.13. Sistem sokongan sosial perlu untuk mengekalkan kepulihan