laporan i-sintesis metil salisilat 2016 (wiri resky amalia)

8/19/2019 Laporan I-sintesis Metil Salisilat 2016 (Wiri Resky Amalia)

1/18

SINTESIS METIL SALISILAT

LABORATORIUM KIMIA FARMASI

FAKULTAS FARMASI

UNIVERSITAS MUSLIM INDONESIA

LAPORAN KIMIA ORGANIK SINTESIS


NAMA : WIRI RESKY AMALIA

STAMBUK : 15020140074

KELAS : C3

KELOMPOK : 2

ASISTEN : INDAH MUTMAINAH

FAKULTAS FARMASI

UNIVERSITAS MUSLIM INDONESIA

MAKASSAR

201

WIRI RESKY AMALIA

15020140074 INDAH MUTMAINAH


2/18


BAB I PENDAHULUAN

1.1 Latar BelakangS!"!#$% &'() *%+!$',-% .',/' M!$% '%%'$ !#-"'+'( !(&'/'

''% &'() $!#+'(*-() *'' %(&'+ )'(*'"-#' *'( *'"'$ *%$!-+'( "'*'

*'-( !#$' )')'() $'(''( )'(*'"-#' G'-$,!#%' " M!$% '%%'$ .'(&'+

*%)-('+'( *'' %(*-$#%6%(*-$#% .'$ 6 .'$'(8 .','( "!/'()%8 %(*-$#%

'+'('( *'( %(-'(

M!$% '%%'$ *'"'$ *%.-'$ !'-% %($!%% *!()'( #!'+%

"!.!($-+'( !$!# !$!#!9%+'% R!'+% !$!#%9%+'% '*'', -'$- #!'+% '($'#'

'' +'#.+%'$ *'( '+, !.!($-+ !$!# T-#-('( '' +'#.+%'$

!.!($-+ !$!# '' +'#.+%'$ E$!# '' +'#.+%'$ %'', -'$-

!(&'/' &'() !()'(*-() )-)- CO2R *!()'( R *'"'$ .!#-"' '+%

'-"-( '#% E$!#%9%+'% *%+'$'%% '' *'( .!#%9'$ *'"'$ .'%+E$!# *%,'%+'( '"'.%' '' +'#.+%'$ *%"'('+'( .!#''

'+, *!()'( .'($-'( +'$'% '' K'$'% %(% .%''(&' '*'', '' -9'$

"!+'$ T!#+'*'() ;-)' *%)-('+'( )' ,%*#)!( +#%*' +!#%()8 $!$'"% +'$'%6

+'$'% %(%

!()'(*-() !.-',


3/18


U($-+ !(%($!% !$% '%%'$ .!#*''#+'( #!'+% !$!#!9%+'%

'($'#' '' '%%'$ *'( !$,'( '.-$ !#$' "!('.','( '' -9'$ "!+'$

!.')'% +'$'%'$#

WIRI RESKY AMALIA



4/18


BAB 2 TINAUAN PU!TA"A

2.1 Te#ri Umum

R!'+% !$!#%9%+'% '*'', -'$- #!'+% '($'#' '' +'#.+%'$ *'('?1

S-'$- !$!# '' +'#.+%'$ %'', -'$- !(&'/' &'() !()'(*-()

)-)- CO2R *!()'( R *'"'$ .!#.!($-+ '+% '-"-( '#% S-'$- !$!# *'"'$

*%.!($-+ *!()'( #!'+% '()-() '($'#' -'$- '' +'#.+%'$ *'( -'$-

'


5/18


('' '%( % 9 /%($!#)#!!( '$'- %(&'+ .!$-- K!)-(''((&' &'() -'

*'' .!#.')'% %(*-$#% !.-'$ "!#%($''( '+'( +*%$' $!#!.-$

!(%()+'$ $%'" $',-((&' P'*' %(*-$#% 9'#'%8 !$% '%%'$ *%)-('+'(

!.')'% .','( '+$%9 *'' .!#.')'% 9#-'% "#*-+ -($-+ !(*'"'$+'(

!9!+ '(')!%+(&' A#' *'( #''(&' &'() +,' ;-)' !.-'$(&' .'(&'+

*%)-('+'( *% %(*-$#% '+'('( '$'- %(-'( *'( %(*-$#% +!$%+ M!$%

'%%'$ *'"'$ *%!+$#'+% *'#% '' *'' .!($-+ %(&'+ '$%#% *'#% $'(''(

G'(*'"-#'8 ('-( !+'#'() !.%, .'(&'+ *%;-"'% "'.#%+ &'() !(%($!%

!$% '%%'$ *'#% '' '%%'$ *'( !$'( S!


6/18


M!$% '%%'$ '*'', !.-', !(&'/' #)'(%+ *'( !#-"'+'(

!.-', !$!# E$!# '*'', !.-', +.%('% *'#% !.-', '' #)'(%+ *'(

!.-', '+, M!$% '%%'$ ;-)' *%+!(' !.')'% %(&'+ )'(*'"-#' *'(

*%$!-+'( !


7/18


'%%'$ *'( !$'( *!()'( !())-('+'( +'$'% '' -9'$ "!+'$ %(%

*%.-$-,+'( '' "

#!'+% +! *''


8/18


BAB 3 MET)DE "E*A

3.1 Alat Praktikum

A*'"-( ''$ &'() *%)-('+'( "'*' ''$ "#'+$%+- &'%$- .'+8 .$

!"#$8 .'$- *%*%,8


9/18


WIRI RESKY AMALIA



10/18


11/18


3 R!(*'!( ¿

Ber at praktek

Berat Teori J 100

¿ 2,37gram

4,256gram J 100

558?

0. *eaksi

A' S'%%'$ !$,'( M!$% S'%%'$ '%#

-.2 Pema+asan

M!$% '%%'$ !#-"'+'( $-#-('( *'#% '' '%'$ &'() "'%()

"!($%() !

'$'- !.')'% +'$'% P!#$'' $'' *%$%.'() 4 )#' '' '%%'$ *'(

WIRI RESKY AMALIA



12/18


*%'-++'( +!*'' '.- '' *'$'# +!-*%'( *%$'.', !$'( '.-$!

1 L P#! #!'+% '+'( .!#'()-() '.'$ $'("' '*'(&' +'$'% .!#-"'

'' +-'$8 $!$'"% #!'+% '+'( !(


13/18


.!(%() P!('.','( +'%- +#%*' '+'( .!#9-()% -($-+ !('#%+ +'(*-()'(

'%# "'*' !$% '%%'$8 ')'# !$% '%%'$ &'() *%*'"'$+'( !.%, -#(%

S!$!', "!('.','( +'%- +#%*' '(,%*#'$8 !$% '%%'$ *%.%'#+'(

+!#%() .!#'' *!()'( +'%- +#%*' '(,%*#'$ !'' !'' *'' )!'

-+-#8 !'(;-$(&' *% -+-# @-! '#-$'( &'() *%"!#!, *'( *%"!#!, "!#!(

#!(*'!( *'#% !$' '%%'$ '*'', 558?

A*'"-( 9'+$# +!'','( *'' "#'+$%+- %(% +!$%*'+ $!%$%'( "#'+$%+'(

$!#,'*'" "!('.','( A' -9'$ "!+'$ &'() !,'#-(&' *%$'.',+'( !*%+%$

*!% !*%+%$8 !,%())' #!'+% &'() *%%()%%(+'( $%*'+ !"-#(' *'( "!.!($-+'(

!$% '%%'$ .%' *%'())'" )')'

WIRI RESKY AMALIA



14/18


BAB PENUTUP

.1 "esimulanB!#*''#+'( ,'% "#'+$%+- &'() $!', *%'+-+'(8 *'"'$ *%%"-+'(

.',/' S%($!% !$% '%%'$ &'() *%.-'$ *!()'(


15/18


DATA* PU!TA"A

A((%8 200>8 Penuntun Praktikum Kimia Organik 28 UGM : Y)&'+'#$'

A((%8 2018 Penuntun Praktikum Kimia Sintetik 8 UMI : M'+''#

C,''(',8 U8 20108 Pengaruh Lama Pemanasan terhadap Hasil Reaksi Sintesis Metil Salisilat dari Asam Salisilat dan Metanol dengan Katalis Asam Sulfat

Pekat.

D'(%! 2011 Sintesis 2-Hidroksi-N-enil-!en"amida Melalui #sterifikasi Asam

Salisilat $ila%utkan Proses Amidasi $engan enilamida.

D%#;!( POM8 1>7>8 armakope &ndonesia #disi &&& 8 D!"+! RI : '+'#$'

F'$#%('8 T8 *'( W%('#+8 TU8 20138 S&ntesis Metil Salislat UGM : Y)&'+'#$'

F!!(*!( *'( F!!(*!(8 1>?18 Kimia Organik #disi Ketiga 'ilid 28 E#'())' :'+'#$'

I#/'(*%8 D!*%8 20148 #(periment)s of Organi* +hemistr,8 '+'#$': UIN S&'#%9 H%*'&'$-', PIPA6FITK P#! : '+'#$'

T'($%' *'( T#%+'8 20138 Praran*angan Parik Metil Salisilat dari Asam Salisilat dan

Metanol denganKapasitas /.///0on10ahun.

T;'&8 TH8 20028 Oat Oat Penting 8 PT G#'!*%' : '+'#$'

WIRI RESKY AMALIA



16/18


LAMPI*AN

!"EMA "E*A

A' '%%'$ 4 )#' M!$'( '.-$ 1 L

H2SO4 P 385 L

R!9-+ 2 285 ;'

D%*%()%(+'( "'*' ! .'$-

50 L H2O

*%'-++'( *'' C#() "%',

*%"%',+'( !$!# *'( '%#(&'

50 L N'HCO3 5

*%'-++'( *'' C#() "%',

WIRI RESKY AMALIA



17/18


30 L H2O

C#() "%',

D%"%',+'( !$% '%%'$ *'( '%#(&'

D%+!#%()+'( .!#'' +'%- +#%*' '(,%*#'$ !'' !''

U+-# V-!

H%$-() #!(*'!(

WIRI RESKY AMALIA



18/18


4AMBA*

Alat *e5luks

Didinginkan dalam es setela+ emanasan 2 jam

WIRI RESKY AMALIA


laporan i-sintesis metil salisilat 2016 (wiri resky amalia)

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