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    LymphographyLymphographyByBy

    Dr/ Dina MetwalyDr/ Dina Metwaly

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     lymphatic systemlymphatic system

     it is part of the circulatory system, comprising ait is part of the circulatory system, comprising a

    network of lymphatic vessels that carry a clearnetwork of lymphatic vessels that carry a clear

    uid called lymph directionally towards theuid called lymph directionally towards theheart.heart.

     he lymphatic system consists of lymphatic he lymphatic system consists of lymphatic

    organs, a conducting network of lymphaticorgans, a conducting network of lymphatic

    vessels, and the circulatingvessels, and the circulating lymph..

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    The Lymphatic System functionsThe Lymphatic System functions

    Slide 12.1Slide 12.1

    • Transport clean fluids back to the

    blood

    Drains excess fluids from tissues

    • Removes “debris” from cells of

    body

    • Transports fats from digestive

    system

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      Lymphatic !ystemLymphatic !ystem

     hymus hymus

    "land"land

    LymphLymph

    #essels#essels

    Lymph $odesLymph $odes

    !pleen!pleen

     onsils onsils

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    Lymphatic CapillariesLymphatic Capillaries

    • luid leaks through mini!valves into lymph capillaries

    • "igher pressure on the inside closes mini!valves

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    Lymphatic #esselsLymphatic #essels

    • Collects lymph from lymph

    capillaries

    Delivers lymph to lymph nodes

    • Returns fluid to circulatory

    veins near the heart

    • Right lymphatic duct

    • Thoracic duct

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    Lymphatic System StructuresLymphatic System Structures

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    Lymph $odesLymph $odes

    • %ilter lymph &efore it is returned

    to the &lood

    Defense cells in nodes'

    • Medulla houses macrophages

    which engulf and destroy

    foreign su&stances

    • (orte) nurtures lymphocytes

    which provide immune

    response to antigens *corte)+

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    Lymphoid %rgansLymphoid %rgans

    • Several other organs

    contribute to lymphatic

    function

    &' Spleen

    (' Thymus

    )' Tonsils

    *' +eyer,s patches

    igure &('-

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    The SpleenThe Spleen

    • ilters blood

    • Destroys .orn out blood cells

    • orms blood cells in the fetus

    •  /cts as a blood reservoir 

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    The ThymusThe Thymus

    • unctions at peak levels only

    during childhood

    • +roduces hormones 0like

    thymosin1 to program

    lymphocytes

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    TonsilsTonsils

    • Small masses of lymphoid

    tissue around the pharynx

    Trap and remove bacteria and

    other foreign materials

    • Tonsillitis is caused by

    congestion .ith bacteria

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    +eyer,s +atches+eyer,s +atches “Tonsils of the intestine”“Tonsils of the intestine”

    • ound in the .all of the small intestine

    • Capture and destroy bacteria in the

    intestine

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    LymphographyLymphography

    "eneral term applied to the"eneral term applied to the

    radiologic e)amination of'radiologic e)amination of'

      Lymph nodesLymph nodes 

    *lymphadenography+ '*lymphadenography+ '

    radiographic visualiation of theradiographic visualiation of the

    lymph nodes .lymph nodes .

    Lymph #essels' endovascularLymph #essels' endovascular

    in-ection of radiopaue materialin-ection of radiopaue material

    into a lymphatic vesselinto a lymphatic vessel

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    sually done to demonstrate pelvis andsually done to demonstrate pelvis and

    a&domena&domen

    0n-ected in foot0n-ected in foot

    %or a)illary, clavicular area and upper lim&s%or a)illary, clavicular area and upper lim&s

    0n-ected in hand (hecks drainage of lymph0n-ected in hand (hecks drainage of lymph

    nodesnodes

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    0ndications0ndications

    1dema in lim&s &y1dema in lim&s &y

    #isualiation of vessel#isualiation of vessel

    o&structiono&struction

    0nfections0nfections

    2ule out cancer2ule out cancer

    Lymphoma staging 3 (heckLymphoma staging 3 (heckfor metastasisfor metastasis

    !ie, shape, location of!ie, shape, location of

    enlarged nodesenlarged nodes

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    (ontraindications(ontraindications

     4regnancy4regnancy

    4eople with allergies to iodine5&ased4eople with allergies to iodine5&ased

    contrast dyes.contrast dyes. people with severe chronic lung, heart,people with severe chronic lung, heart,

    kidney, or liver disease.kidney, or liver disease.

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    4re 4rocedure4re 4rocedure

    6&tain 4 history6&tain 4 history

    6&tain 4 consent6&tain 4 consent

    Make sure to have all suppliesMake sure to have all supplies

    Make sure the a&sence of contraindications,Make sure the a&sence of contraindications,

    which are cardiovascular or pulmonarywhich are cardiovascular or pulmonary

    diseasedisease

    4ositioning aides and comfort supplies4ositioning aides and comfort supplies

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    (ontrast(ontrast

    7ater &ased *less commonly used as it di8use in7ater &ased *less commonly used as it di8use in

    near&y tissues+.near&y tissues+.

    6il &ased6il &ased

    More commonly usedMore commonly used

    1thiodal1thiodal

    LipodalLipodal

    Dose' he total amount of oily contrast mediumDose' he total amount of oily contrast medium

    in-ected on each side should never e)ceed 9: mLin-ected on each side should never e)ceed 9: mL 

    4rocedure of lower lim&4rocedure of lower lim&

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    4rocedure of lower lim&4rocedure of lower lim&

    lymphography * pedallymphography * pedal

    lymphangiography+lymphangiography+

    0n-ection of mi)ture of local anesthesia ; methylene0n-ection of mi)ture of local anesthesia ; methylene

    &lue violet on the dorsal aspect of the foot &etween the&lue violet on the dorsal aspect of the foot &etween the

    toes.toes.

      longitudinal incision 555< isolation of lymphatic vessellongitudinal incision 555< isolation of lymphatic vessel

    from the surrounding fatty tissuefrom the surrounding fatty tissue

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    visualiation of super=cial collectors aftervisualiation of super=cial collectors aftersu&cutaneous in-ection of contrast materialsu&cutaneous in-ection of contrast material

    9.9.  into the =rst and second inter5metatarsal spacesinto the =rst and second inter5metatarsal spaces

    of the dorsal foot *for super=cial circulation+of the dorsal foot *for super=cial circulation+oror

    >.>.   or lateral retro5malleolar space *for deepor lateral retro5malleolar space *for deep

    circulation+circulation+ $odes in pelvis and a&domen are demonstrated$odes in pelvis and a&domen are demonstrated

    with foot in-ectionwith foot in-ection

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    ? needle or catheter is inserted into a lymphatic? needle or catheter is inserted into a lymphatic

    channel in either the foot or arm, and a contrastchannel in either the foot or arm, and a contrast

    medium is in-ected into the &ody at a very slow ratemedium is in-ected into the &ody at a very slow rate

    *appro)imately @: to A: minutes for all the contrast*appro)imately @: to A: minutes for all the contrast

    medium to &e in-ected+.medium to &e in-ected+.

    ? uoroscope is used to follow the dye as it spreads? uoroscope is used to follow the dye as it spreads

    through the lymphatic system through the legs, into thethrough the lymphatic system through the legs, into the

    groin, and along the &ack of the a&dominal cavity.groin, and along the &ack of the a&dominal cavity.

    6nce the contrast medium is in-ected, the catheter is6nce the contrast medium is in-ected, the catheter is

    removed, and the incisions are stitched and &andaged.removed, and the incisions are stitched and &andaged.

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    %ilming%ilming

    5rays are usually taken 9 C2 after pressure5rays are usually taken 9 C2 after pressure

    in-ection that takes a&out E minutesin-ection that takes a&out E minutes

    ?fter 9 hour?fter 9 hour

    > hrs> hrs

    F hrs *if needed+F hrs *if needed+

    G>hrs *if needed+G>hrs *if needed+ %irst hour%irst hourHH (ontrast in lymph ducts(ontrast in lymph ducts

    > hours> hours HH 0f lymph nodes0f lymph nodes

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    ?fter 9 hourH?fter 9 hourH

    LymphangiogramsLymphangiograms

    the =rst =lms are takenthe =rst =lms are taken

    usually of the lymphusually of the lymph

    vesselsvessels the upper &ody orthe upper &ody or

    any area of interest.any area of interest.

     hese =rst ims are called hese =rst ims are called

    ILymphangiogramsJKILymphangiogramsJK

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    LymphadenogramsLymphadenograms

    > hours after the> hours after the

    LymphangiogramsLymphangiograms

    are taken the patientare taken the patient

    has to come &ack tohas to come &ack to

    have the =lms takenhave the =lms taken

    of the lymphof the lymph nodesnodes

    calledcalled

    IlymphadenogramsKJIlymphadenogramsKJ

    li &li &

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    upper lim&upper lim&

    lymphographylymphography

      in-ection of contrast agent in a collector ofin-ection of contrast agent in a collector of

    dorsal radio5carpal surface *for super=cialdorsal radio5carpal surface *for super=cial

    circulation+ or ulnar retro5styloid locationcirculation+ or ulnar retro5styloid location

    *for deep circulation+*for deep circulation+

    radiography of the lymphatic channels fromradiography of the lymphatic channels from

    forearm to a)illary lymph nodesforearm to a)illary lymph nodes

    Li & Li &

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    pper Lim&pper Lim&

    LymphographyLymphography

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    Normal appearances andNormal appearances and

    variationsvariations9.9. $ormal appearance of lymph nodes.$ormal appearance of lymph nodes.

    a+a+ Lymphogram *=lling phase+' shows a homogeneousLymphogram *=lling phase+' shows a homogeneous

    appearance of the lymph nodes.appearance of the lymph nodes.

    &+&+ Lymphogram *nodal phase+' shows a smooth peripheralLymphogram *nodal phase+' shows a smooth peripheral

    indentation *arrowheads+, which corresponds to the hilarindentation *arrowheads+, which corresponds to the hilar

    area.area.

    a) filling  b) Nodal

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    4ara5aortic nodes have proved to4ara5aortic nodes have proved to

    &e the most relia&le group for&e the most relia&le group for

    showing features of highshowing features of high

    diagnostic accuracydiagnostic accuracy

     he cisterna chyli is usually a he cisterna chyli is usually a

    saccular structure less than E cmsaccular structure less than E cm

    in length usually lies at thein length usually lies at themidline of the &ody of L9 &ut maymidline of the &ody of L9 &ut may

    also &e situated on either side ofalso &e situated on either side of

    the midline.the midline. Lymphogram shows normal

    cisterna chyli and the abdominalsegment of the thoracic duct.

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     he thoracic duct sharply merges into the -unction of he thoracic duct sharply merges into the -unction of

    the left su&clavian vein and left internal -ugular veinthe left su&clavian vein and left internal -ugular vein

    !ome rarely seen nodes are situated e)trinsically to!ome rarely seen nodes are situated e)trinsically to

    the usual lymphographic regions, such as thethe usual lymphographic regions, such as the

    popliteal, posterior intercostal, mediastinal, &ilateralpopliteal, posterior intercostal, mediastinal, &ilateral

    hilar, paratracheal, and supraclavicular nodeshilar, paratracheal, and supraclavicular nodes

    Figure: Lymphogram shows Normal

    appearance of the thoracic duct. the termination

    of the thoracic duct at the left subclavian-

     jugular venous anastomosis at the base of the

    neck 

    0li l i ti L h ti0li l i ti L h ti

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    0liopelvic5aortic Lymphatic0liopelvic5aortic Lymphatic

    !ystem!ystem

    0li l i ?&d i ti0li l i ?&d i ti

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    0liopelvic ?&dominoaortic0liopelvic ?&dominoaortic

    Lymph $odesLymph $odes

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    0nguinal 2egion0nguinal 2egion

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    LymphographyLymphography

    Lipiodol lymphography: Left image: fter the injection of contrast material

    !lymphangiographic phase) the normal lymphatic vessels of the minor pelvis

    are visuali"ed. #ight image: $% hours after the injection normal inguinal&

     pelvic and paralumbar lymph nodes are demonstrated !nodal phase).

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    complicationscomplications

     he ma-or complications of lymphography are he ma-or complications of lymphography are

    caused &y the vital dye and contrast materialscaused &y the vital dye and contrast materials

    rather than the techniuerather than the techniue Ma-or freuent complication'Ma-or freuent complication'

    9.9. pulmonary oil em&oliationpulmonary oil em&oliation

    >.>. 4ulmonary infarction4ulmonary infarction

    .. hypersensitivity to methylene &lue dye andhypersensitivity to methylene &lue dye and

    ethiodied oilethiodied oil

    2are complication'2are complication'

    9.9.  intraalveolar hemorrhageintraalveolar hemorrhage

    >.>.  hypothyroidismhypothyroidism

    ..  systemic arterial em&oliation to the &rain orsystemic arterial em&oliation to the &rain or

    kidneykidney

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    4ost 4rocedure4ost 4rocedure

    9.9. 7atch for signs of infection7atch for signs of infection

    !welling red and warm to touch!welling red and warm to touch

    ?ccompanied &y a fever?ccompanied &y a fever

    (ontact D2 right away(ontact D2 right away

    >.>. Drink lots of waterDrink lots of water

    .. Ma-or swelling in one lim&Ma-or swelling in one lim&

    1specially lim& in-ected1specially lim& in-ected

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    (onclusion(onclusion

     his procedure has largely &een replaced &y non5 his procedure has largely &een replaced &y non5

    invasive M20 or ( procedures.invasive M20 or ( procedures.

      Cowever, lymphography has the uniue capa&ilityCowever, lymphography has the uniue capa&ility

    of demonstrating internal architecturalof demonstrating internal architectural

    derangements within normal5sied lymph nodes.derangements within normal5sied lymph nodes.

     his highly valua&le advantage makes his highly valua&le advantage makes

    lymphography diagnostically more accurate than (lymphography diagnostically more accurate than (

    *which demonstrates sie rather than architecture+*which demonstrates sie rather than architecture+

    Lymphography still has a cornerstone role inLymphography still has a cornerstone role in

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    3 ?N 3 ?N