DAFTAR ISIHalaman

HALAMAN JUDUL ...................................................................................................

i

PRAKATA....................................................................................................................

ii

DAFTAR ISI ................................................................................................................

iii

DAFTAR SINGKATAN .............................................................................................

iv

DAFTAR TABEL ........................................................................................................

v

DAFTAR GAMBAR ...................................................................................................

vi

INTISARI ....................................................................................................................

viii

BAB I. PENDAHULUAN .........................................................................................

1

1.1. Latar Belakang........................................................................................

1

1.2. Rumusan Masalah ..................................................................................

3

1.3. Tujuan Penelitian ...................................................................................

3

1.4. Manfaat Penelitian .................................................................................

4

BAB II. TINJAUAN PUSTAKA ................................................................................

5

2.1. Malondialdehide (MDA).....................................................................

5

2.1.1. Definisi MDA................................................................................

5

2.1.2. Hubungan Radikal Bebas dengan Kadar MDA.............................

5

2.1.3. Faktor yang Mempengaruhi Oksidan Tubuh................................. 7

2.1.4. Pengukuran Radikal Bebas............................................................

8

2.2. Anemia................................................................................................ 9

2.2.1. Definisi Anemia ............................................................................

9

2.2.2. Jenis Anemia Berdasarkan Penyebab ...........................................

9

2.2.3. Efek NaNO2 Terhadap Anemia.....................................................

10

2.2.4. Pencegahan dan Pengobatan Anemia............................................

11

2.3. Katuk (Sauropus androgynus)............................................................ 11

2.3.1. Karakteristik Daun Katuk..............................................................

11

2.3.2. Taksonomi......................................................................................

13

2.3.3. Kandungan Gizi dan Manfaat Daun Katuk....................................

13

2.3.4. Klorofil Daun Katuk......................................................................

13

2.3.4.1. Definisi Klorofil.................................................................

13

2.3.4.2. Struktur Kimia Klorofil......................................................

14

2.3.4.3. Sifat Klorofil......................................................................

14

2.4. Cu-klorofillin ......................................................................................

16

2.4.1. Definisi Cu-klorofilin.....................................................................

16

2.4.2. Mekanisme Kerja Cu-klorofilin.....................................................

16

2.4.2. Penggunaan Terapi dan Dosis Cu-klorofilin..................................

17

2.5. Hewan Coba........................................................................................

17

2.6. Hubungan antara Klorofil Daun Katuk dengan Kadar MDA..............

18

2.7. Kerangka Teori....................................................................................

29

2.8. Kerangka Konsep................................................................................

19

2.9. Hipotesis .............................................................................................

19

BAB III.METODOLOGI PENELITIAN ....................................................................

20

3.1. Jenis Dan Rancangan Penelitian ............................................................

20

3.2. Variabel Dan Definisi Operasional ........................................................

20

3.2.1. Variabel Penelitian..................................................

20

3.2.2. Definisi Operasional ............................................................

20

3.3. Populasi Dan Sampel .............................................................................

21

3.3.1. Populasi Penelitian................................................................

21

3.3.2. Sampel Penelitian..................................................................

21

3.4. Instrumen Dan Bahan Penelitian............................................................

22

3.4.1. Instrumen Penelitian.............................................................

22

3.4.2. Bahan penelitian....................................................................

23

3.5. Cara Penelitian .......................................................................................

24

3.5.1. Persiapan Penelitian .............................................................

24

3.5.2. Pelaksanaan Penelitian..........................................................

25

3.5.3. Pengambilan Darah ..............................................................

25

3.5.4. Pengukuran Kadar MDA (Malondialdehide) ......................

26

3.5.5. Alur Kerja Penelitian............................................................

27

3.6. Tempat Dan Waktu Penelitian ...............................................................

28

3.6.1........................................................................................................Tempat Penelitian

28

3.6.2........................................................................................................Waktu Penelitian

28

3.7. Analisa Hasil .........................................................................................

28

BAB IV HASIL PENELITIAN DAN PEMBAHASAN .............................................

29

4.1.................................................................................................................. Hasil Penelitian

................................................................................................................. 29

4.2..................................................................................................................Pembahasan

................................................................................................................. 30

BAB V KESIMPULAN DAN SARAN .....................................................................

34

5.1.................................................................................................................. Kesimpulan

................................................................................................................. 34

5.2.................................................................................................................. Saran

34

DAFTAR PUSTAKA ..................................................................................................

35