In vitro antibacterial and time-kill evaluation of phosphanegold(I)

dithiocarbamates, R3PAu[S2CN(iPr)CH2CH2OH] for R = Ph, Cy and Et,

against a broad range of Gram-positive and Gram-negative bacteria

J.-H. Sim • C.-H. Khoo • Y.-K. Cheah (*)

Department of Biomedical Science, Faculty of Medicine and Health Sciences, University Putra

Malaysia, 43400 Serdang, Selangor Darul Ehsan, Malaysia

E Telephone: +60 3 8943 6178; Facsimile number: +60 3 8947 2343; E-mail:

ykcheah@medic.upm.edu.my

Nazzatush Shimar Jamaludin • Siti Nadiah Binti Abdul Halim • Hoi-Ling Seng • Edward R. T.

Tiekink (*)

Department of Chemistry, University of Malaya, 50603 Kuala Lumpur, Malaysia

Telephone: +60 3 7967 6775; Facsimile number: +60 3 7967 4193; E-mail:

Edward.Tiekink@gmail.com

Electronic supplementary material

Compound λ excitation, nm; (ε) λ emission, nmx 10-4 M x 10-5 M x 10-6 M

1 299 (ε = 4,838) 300598

276 (ε = 33,140) 276550

284 (ε = 196,000) 285568

2 384 (ε = 16,490) 383309 (ε = 22,100) 311

619283 (ε = 291,800) 284

566

3 311 (ε = 14,095) 311309 (ε = 20,250) 309275 (ε = 238,100) 550

Table S1. UV/vis absorption and photoluminescence data (nm) recorded at room

temperature in DMSO solution for 2–4. The units for the extinction

coefficient (ε) are cm-1 M-1.

(a)

(b)

Figure S1. Calculated (red trace) and experimental (blue trace) PXRD patterns for (a) 2 and (b)

3. These show that the bulk sample is the same as the single crystal in each case.