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Editorial Team
Editor-in-Chief
1. Prof. nzw. dr hab. inz. Lech M. Grzesiak, Warsaw University of Technology, Poland
Managing Editor
1. Assoc. Prof. Dr. Tole Sutikno, Universitas Ahmad Dahlan, Indonesia 2. Dr. Auzani Jidin, Universiti Teknikal Malaysia Melaka (UTeM), Malaysia
Associate Editors
1. Prof. Dr. Faycal Djeffal, University of Batna, Batna, Algeria
2. Prof. Dr. Geetam Singh Tomar, University of Kent, United Kingdom 3. Prof. Dr. Govindaraj Thangavel, Muthayammal Engineering College, India 4. Prof. Dr. Kewen Zhao, Qiongzhou University, China 5. Prof. Dr. Sayed M. El-Rabaie, Minufiya University, Egypt 6. Prof. Dr. Tarek Bouktir, Ferhat Abbes University, Setif, Algeria 7. Prof. Dr. Ahmad Saudi Samosir, Universitas Lampung (UNILA), Indonesia 8. Prof. Abdel Ghani Aissaoui, University of Bechar, Algeria, Algeria 9. Prof. ing. Salvatore Favuzza, Ph.D., University of Palermo, Italy 10. Assoc. Prof. Dr. Angela Amphawan, Universiti Utara Malaysia, Massachusetts Institute of Technology,
Malaysia 11. Assoc. Prof. Farrokh Attarzadeh, Ph.D., University of Houston, United States
12. Assoc. Prof. Dr. Jaime Lloret Mauri, Polytechnic University of Valencia, Spain 13. Assoc. Prof. Dr. Mochammad Facta, Universitas Diponogoro (UNDIP), Indonesia 14. Assoc. Prof. Dr. M L Dennis Wong, Heriot-Watt University, Malaysia 15. Assoc. Prof. Dr. Naci Genc, Yuzuncu Yil University, Turkey 16. Assoc. Prof. Dr. Wudhichai Assawinchaichote, King Mongkut's University of Technology Thonburi, Thailand 17. Asst. Prof. Dr. Luca Cassano, Politecnico di Milano, Italy 18. Dr. Deris Stiawan, C|EH, C|HFI, Universitas Sriwijaya, Indonesia 19. Dr. Junjie Lu, Broadcom Corp., United States 20. Dr. Laura García-Hernández, University of Córdoba, Spain 21. Dr. Mehrdad Ahmadi Kamarposhti, Jouybar Branch, Islamic Azad University, Iran, Islamic Republic of 22. Dr. Mohd Ashraf Ahmad, Universiti Malaysia Pahang, Malaysia 23. Dr. Munawar A Riyadi, Universiti Teknologi Malaysia, Malaysia
24. Dr. Nidhal Bouaynaya, University of Arkansas at Little Rock, Arkansas, United States 25. Dr. Nizam Uddin Ahamed, University of Calgary, Canada 26. Dr. Renjie Huang, Washington State University, United States 27. Dr. Ranjit Kumar Barai, Jadavpur University, India 28. Dr. Shadi A. Alboon, Yarmouk University, Jordan 29. Dr. Vicente Garcia Diaz, University of Oviedo, Spain 30. Dr. Yin Liu, Symantec Core Research Lab, United States 31. Dr. Zheng Xu, IBM Corporation, United States
Vol 8, No 6 December 2018
DOI: http://doi.org/10.11591/ijece.v8i6
Table of Contents
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International Journal of Electrical and Computer Engineering (IJECE)
Vol. 8, No. 6, December 2018, pp. 5415~5424
ISSN: 2088-8708, DOI: 10.11591/ijece.v8i6.pp5415-5424 5415
Journal homepage: http://iaescore.com/journals/index.php/IJECE
Improving Hierarchical Decision Approach for Single Image
Classification of Pap Smear
Dwiza Riana1, Yudi Ramdhani2, Rizki Tri Prasetio3, Achmad Nizar Hidayanto4
1STMIK Nusa Mandiri, Indonesia 2,3Universitas BSI, Indonesia
4Universitas Indonesia, Indonesia
Article Info
ABSTRACT
Article history:
Received Mar 28, 2018
Revised Jul 27, 2018 Accepted Aug 7, 2018
The single image classification of Pap smears is an important part of the
early detection of cervical cancer through Pap smear tests. Unfortunately,
most classification processes still require accuracy enhancement, especially
to complete the classification in seven classes and to get a qualified
classification process. In addition, attempts to improve the single image
classification of Pap smears were performed to be able to distinguish normal
and abnormal cells. This study proposes a better approach by providing
different handling of the initial data preparation process in the form of the
distribution for training data and testing data so that it resulted in a new
model of Hierarchial Decision Approach (HDA) which has the higher
learning rate and momentum values in the proposed new model. This study
evaluated 20 different features in hierarchical decision approach model based
on Neural Network (NN) and genetic algorithm method for single image
classification of Pap smear which resulted in classification experiment using
value learning rate of 0.3 and momentum of 0.2 and value of learning rate of
0.5 and momentum of 0.5 by generating classification of 7 classes (Normal
Intermediate, Normal Colummar, Mild (Light) Dyplasia, Moderate Dyplasia,
Servere Dyplasia and Carcinoma In Situ) better. The accuracy value
enhancemenet were also influenced by the application of Genetic Algorithm
to feature selection. Thus, from the results of model testing, it can be
concluded that the Hierarchical Decision Approach (HDA) method for Pap
Smear image classification can be used as a reference for initial screening
process to analyze Pap Smear image classification.
Keyword:
Cervical cancer
Genetic algorithm
Hierarchical Decision
Approach (HAD)
Neural Network (NN)
Pap smear
Copyright © 2018 Institute of Advanced Engineering and Science.
All rights reserved.
Corresponding Author:
Dwiza Riana,
STMIK Nusa Mandiri Jakarta,
Jalan Damai no 8 Jakarta Selatan, Indonesia.
Email: [email protected]
1. INTRODUCTION
Research on the classification of single Pap smear image has been done. This attempt was intended
to digitize the introduction of early detection of cervical cancer. As known that one type of malignant cancer
that attacks women according to WHO body with the massive number of patients in Indonesia is cervical
cancer. It is no wonder that Indonesia became one of the countries that have a lot of cervical cancer patients.
Cervical cancer is generally caused by a virus called Human Papilloma Virus (HPV). Sexual intercourse
became the largest case of HPV [1].
Pap smear is a method of early detection of cervical cancer. The process applied on Pap smear
continuously and consistently in a country will help prevent early cervical cancer. This method was
performed by a Pathologist in a clinical pathology laboratory, in which tests were performed on a woman's
squamous epithelium. The results of pathologist's examination with a Pap smear will show whether the
5416 ISSN: 2088-8708
woman has normal or abnormal cells [2]. There are various classifications in Pap Smear, but in this study,
Int J Elec & Comp Eng, Vol. 8, No. 6, December 2018 : 5415 - 5424
Pap smear images are classified up to 7 classes [3], in which the first three classes are normal cell class
categories including Normal Superficial, Normal Intermediate, and Normal Colummar while the next four
classes of abnormal cell categories are: Mild (Light) Dyplasia, Moderate Dyplasia, Dyplasia and Carcinoma
In Situ [4].
General examination used to detect cervical cancer in Pap smear method is to prevent and detect the
presence of pre-cancer and cancer situation in cervical cell samples. The problem of Pap smear image
classification is caused by Pap smear image having unique characteristic so that the automatic identification
of Pap smear image is a challenging problem for researchers. Different cell conditions and structures with
high variations of image conditions make the identification and classification process of the Pap smear image
need special handling. Particularly the process of Pap smear image classification until now is still
experiencing difficulties and requires techniques and methods of classification that have a high accuracy.
The use of data mining so far is commonly used to obtain optimal information from a large group of
large databases that have complexity [5]. In a study of single Pap smear image classification found in the
Herlev dataset [4], data mining was used to get information from 20 features in the data to identify pathologic
cases of cervical cancer. The previous researches which aimed to identify pathological cases with the same
dataset include the study of classification methods on normal class images [6-8] and classification of
abnormal classes [9]. Besides the classification of previous research forms, some researchers aim to segment
the Pap smear image [6],[10]. Even the effort to identify the best features to solve the pathological case of
cervical cancer has also been done. Feature [11] and texture analysis [6], [12] are some of the examples. The
combination of several features (20 features) referring to 7 classes of diverse cases of pathological cancer,
causing difficulties in the classification for 7 classes in this Pap smear image where it remains a challenge for
researchers. Some algorithms aimed at selecting features such as genetic algorithms [13] perform a feature
selection process by selecting some of the best individuals. Individual taking should be done randomly and
proportionally including the proportion of its quality.
The proposed HDA classification model on single Pap smear image was started [14] from when the
Pap smear classification model offered new process stages by utilizing both quantitative and qualitative
features that was utilization of Importance Performance Analysis as the basis of the proposed multi-stage
classification. The results of this study still have difficulties in classification for moderate dysplasia and
severe dysplasia class [14].
The next attempt to classify the image of cervical cancer was to apply the Genetic Algorithm (GA)
for feature selection. Furthermore, to classify healthy cells and cancer cells, we used SVM algorithm
(Support Vector Machine) [15]. The results show that genetic algorithm is a better method for selection of
features and optimization of parameters.
In this study, NN was selected as a tool of analysis on Papsmear image dataset used. The use of this
algorithm was to make data prediction and identify pathological cases of cervical cancer to be handled. The
use of NN for medical data classification is commonly used such as classification to predict mortality
prediction [16]. Optimization on NN algorithm can be done with the aim of improving the performance of
NN [17].The most commonly used optimization method is GA, Particle Swarm Optimization (PSO), and Ant
Colony Optimization [18]. In this study, GA was selected as a feature selection algorithm. GA is one of
algorithms that can select a relevant feature subset, learning rate, momentum, and initialization and weight
optimization.
Based on the previous research [19], we focused this research to improve classification accuracy in
the best model of the classification result based on the HDA model for single-cell Pap smear image
classification. The comparison of classification results was done by using NN algorithm and feature
optimization using GA to determine the increase of accuracy. The results show that there is a significant
increase of accuracy from the proposed HDA model.
In this paper we propose methods for Pap smear cell image classification aimed at two specific
objectives: a) selection of the best features on 20 features of pap smear and b) Pap smear image classification
approach using hierarchial decision approach stage. Thus there are two main contributions in our paper. First,
features of the Pap smear image that are not relevant in the classification process are not used like the longest
diameter nucleus and nucleus roundness. Second, the uses of the hierarchial decision approach make the
classification process more effective and increase the accuracy of classification results. In this way the
automatic classification process to help pathologist allows to be realized.
This method is based on feature selection for less relevant features by using genetic algorithms and
generates relevant features to be used in subsequent classification processes. This method combines the
knowledge on the variations of classification stages between Pap smear and hierarchial decision approach
class by optimizing the value of learning rate and momentum on NN algorithm. Based on this fact we
propose a method that can classify Pap smear image into 7 classes which are 3 normal classes and 4
Int J Elec & Comp Eng ISSN: 2088-8708 5417
abnormal classes. This method exploits the features of the nucleus and cytoplasm through feature selection.
Improving Hierarchical Decision Approach for Single Image Classification of Pap Smear (Dwiza Riana)
Finally, this method is evaluated by using 917 sample dataset and has 20 features, divided into 90% training
data and 10% testing data. The evaluation process uses applications built to support the proposed method.
The reminder of this paper is organized as follows: section 2 about related work, section 3 about research
method used in the study. Section 4 describes the results and analysis, then followed by conclusions and
further research plans.
2. RELATED WORK
The automatic hybrid segmentation classification approach to select and enhance the segmentation
of nucleus cells for Pap smear test images by using nested hierarchical portioning, segmentation level
selection, and SVM classifier was already performed. The purpose of merging the end of the segmentation is
to avoid over segmentation. The segmentation was done with morphological algorithm (watershed) and
hierarchical merging (waterfall) algorithm based on spectral information and shape information as well as
class information. SVM classifier is used to separate two classes of regions that are the nucleus and not the
nucleus area (cytoplasm and background) by using a feature set (morphometric, edge-based, and convex hull-
based). The results of segmentation and classification were compared with the segmentation provided by
pathologist and showed improvement in the proposed method [20]. Unfortunately, this research has not yet
reached the classification process of Pap smear image.
GA has been used in previous research and is considered as a better method for feature selection and
parameter optimization in Pap smear images on the same dataset [15]. Support Vector Machine (SVM)
Algorithm is used for classification. With this structure, new cells can be classified by observing the best
feature values for cancer cell classification as cancer cells or benign cells. Unfortunately, the results show
that the effectiveness of this method has not given the highest accuracy for the classification of 7 classes [15].
The hybrid ensemble technique is used for Pap smear image classification with the addition of new
data [21] [22]. By comparing the methods of NN and SVM. The research stages are not thoroughly
conducted in all class conditions, so the results obtained apply only to the class according to the simplified
stages where the research does not produce a classification model of 7 classes but only presents class recall
data [21].
This study compares Linear Discriminant Analysis (LDA) algorithm and Naïve Bayes algorithm to
obtain the best classification results. The result of classification of LDA algorithm has poor accuracy on 7
classes whereas for Normal and Abnormal class classification, the result has good enough accuracy, and
there is difficulty for abnormal classification with low accuracy value. The low accuracy of the abnormal
class affects the classification into 7 classes [23].
The research that tried to overcome the difficulties of single Pap smear image classification in 7
classes was done by [24]. This study observed a number of classes that has different amounts of data, ie, the
dataset has a class with a number of different and unbalanced classes. Another condition is that the data has
features that are suspected to be irrelevant, so it is still difficult to classify especially abnormal classes. To
handle the class imbalance, this study used ensemble method (Bagging). For handling data that HDA features
and HDA no contribution, we made feature selection of Greedy Forward Selection. Furthermore, Naïve
Bayes was used as learning algorithms. Although this method can handle imbalance classes, but the
classification of 7 classes has not achieved the maximum results [24].
We have implemented Pap smear classification algorithms by using NN classification algorithm and
feature selection by using GA. The best model of the classification result became the Hierarchical HDA
model, a new classification approach for Pap Smear image. The comparison of classification results by using
NN algorithm and feature optimization by using GA to determine the increase of accuracy was conducted.
Pap smear image classification into 7 classes using HDA method has good classification value while
classification using NN algorithm and feature optimization using GA have lower value compared to HDA
algorithm [19]. However, the present study is an improvement of the research by giving special attention to
the more proportional initial data-sharing process by using split validation method that improves the process
of previous research methods. This resulted in accuracy values for both normal and abnormal classification,
and the classification of 7 classes experienced a significant increase.
3. RESEARCH METHOD
3.1. Data Collection
At this stage, we determined the data to be processed, searched for available data, obtained the
additional data required, and integrated all data into data sets including variables required in the process. The
data used for training and testing is secondary data classified carefully by cyto-technicians and doctors. To
Int J Elec & Comp Eng, Vol. 8, No. 6, December 2018 : 5415 - 5424
Initial Data Processing
20 Feature Harlev Dataset
Genetic Algorithm Feature
Selection
Evaluation and
Validation
Experiments and Model Testing
Initial
Population
Fitness
Evaluation
Initial
Population
Problem
Identification Testing Data
30%
Training Data
70%
Crossover and
Mutation
Individual
Selection
Hierarchical Decision
Approach (HDA)
Class 6 Class 5
Class 7 Class 5 and 6 Class 4 Class 3 Class 2 Class 1
Abnormal Normal
Parameter Optimized
Neural Network
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improve the classification of Pap smear cell images in this experiment we used Herlev 917 data [4].
In Table 1, it can be seen that the 20 features found in the dataset feature was optimized by using GA.
Table 1. The Feature of Herlev Dataset [4] Name Of Feature Name Of Feature Name Of Feature Name Of Feature
Nucleus Area or Kerne_A
Nucleus Shortest Diameter or KerneShort
Cytoplasm Longest Diameter or CytoLong
Nucleus Realtive Position or KernePos
Cytoplasm Area or Cyto_A
Nucleus Longest Diameter or KerneLong
Cytoplasm Elongation or CytoElong
Nucleus Maximum or KerneMax
N/C ratio or K/C Nucleus Elongation or KerneElong
Cytoplasm Roundness or CytoRund
Nucleus Minimum or KerneMin
Nucleus Brightness or Kerne_Ycol
Nucleus Roundness or KerneRund
Nucleus Perimeter or KernePeri
Cytoplasm Maximum or CytoMax
Cytoplasm Brightness or Cyto_Ycol
Cytoplasm Shortest Diameter or CytoShort
Cytoplasm Perimeter or CytoPeri
Cytoplasm Minimum or CytoMin
3.2. Proposed Method
At this stage the data was analyzed and grouped into variables that are related to each other. After
the data was analyzed, the models according to the data type were applied. Data sharing into training data and
test data was also required for modeling. This study will select and apply appropriate techniques for Pap
smear image classification. The first stage in this study was to divide the Pap smear cell dataset into two parts
ie, traning data and testing data. The next step was to perform the best feature selection in the Pap smear
image dataset by using GA, and then the selected feature was classified by using NN algorithm. The best
model from the classification result was used as HDA model, so a new classification method approach was
proposed for Pap smear image. The results of the model classification will be measured with an accuracy
value. The research design can be seen in Figure 1.
Classification Results
Figure 1. Research Design
a) Initial Data Processing
In this stage, data selection was conducted. The data was cleaned and transformed into the desired
shape so that it can be done in preparation of model making. At this stage, exploration of the datasets
Improving Hierarchical Decision Approach for Single Image Classification of Pap Smear (Dwiza Riana)
Int J Elec & Comp Eng ISSN: 2088-8708 5419
provided is required. First of all, it is known that the main goal to be achieved is to know the best
classification result of Pap smear cell image. This study used Herlev dataset with the records of 917. To test
the model developed, the data would be divided into two parts, namely training data and data testing. The
data training was used for model development while data testing was used for model testing. It is known that
the amount of data is 917 with a division of 70% (642) used for training data and 30% (275) used for data
testing. The next stage was to select data that wuold be used as training data and data testing by using split
validation. Furthermore, the feature selection method was performed in this research which is GA method.
GA create a population composed of many individuals that evolve according to certain selection rules that
have optimization determination and value.
b) Experiments and Model Testing
At this stage the proposed model will be tested to see the results of a rule that will be utilized in
decision making. This research will conduct experiments on the classification of data mining using NN
algorithm. The modeling will be done by using Rapidminer software. The models that have been obtained are
transformed into the programming language of Visual Basic .Net 2017, and modeling translation of research
design that has been done before are performed because the model of HDA cannot be done on software
Rapidminer programming.
c) Evaluation and Validation At this stage an evaluation of the model determined to find out the level of model accuracy was
done. The evaluation was performed by using the confusion matrix table to determine the algorithm
performance measurement on the classification algorithm model. The measured performance is Accuracy.
The validation performed used the data that had been divided manually into testing data and training data.
The model performance will be compared with NN algorithm by performing feature optimization by using
GA and compared with Neural Netwrok algorithm without doing optimization. Accuracy was used to
compare the results so that the results obtained are more accurate.
4. RESULTS AND ANALYSIS
In this research, we will perform feature selection experiments by using GA and Pap smear
classification by using NN algorithm. The experiments were conducted by using Herlev dataset where the
initial data processing had been done with the distribution of training and testing data. In this section we will
show the experimental results by using the NN algorithm and feature selection using GA by using 20
attributes shown in Table 2 in the Herlev dataset.
In the early stages of this research, the process of separation of traning data and testing data was
conducted, and the feature selection using Genetic Algortihm was then performed. The best attribute will be
used as the Pap smear classification model using NN method. The classification process using NN algorithm
was done by optimizing the best value of NN algorithm parameter with the value of Learning Rate and
Momentum into 2 models. The first model used the learning rate (lr) value of 0.3 and momentum (m) of 0.2
while the second model uses the learning rate (lr) value of 0.5 and momentum (m) of 0.5. Furthermore, the
highest accuracy value analysis was used for the HDA model. From the results, it is known that the value of
learning rate and momentum greatly affects the accuracy of the classification.
Table 2. Classification Result of NN Algorithm and GA No Type Of Classification NN GA + NN (0.3 lr and 0.2 m) GA +NN (0.5 lr and 0.5 m)
1 7 classes 64.00% 70.18% 66.91% 2 Normal & Abnormal 93.12% 96.01% 97.10%
3 Normal 1,2,3 97.22% 98.61% 100% 4 Abnormal 4, 5&6, 7 57.14% 74.88% 73.40%
5 Abnormal 5&6 74.76% 85.44% 84.47%
In Table 2, the classification comparison result shows that the classification with 7 classes using NN
algorithm with the accuracy value of 64.00% after using feature selection by using GA and classification by
using NN algorithm with the learning rate of 0.3 and momentum of 0.2 experiences the improvement of
accuracy with a value of 70.18% and with the value of learning rate of 0.5 and momentum of 0.5 but
produces an accuracy value of 66.91% where the accuracy results still look less.Thus, the process of
classification using the HDA model by taking the best model in each classification was done. From the best
classification result of each class, the best model was taken for the formation of HDA model. From the model
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whose highest accuracy value had been known, the best feature separation using GA was performed with the
distribution of data shown in Table 3.
This stage will perform an evaluation that aims to determine the level of accuracy of the
classification testing results using NN algorithm and feature selection using GA by counting the amount of
testing data that can be classified correctly. The test was done by using rapidminer software to get the best
model and get the result of accuracy value. After obtaining the best model of the results obtained, then the
process of classification using HDA was conducted to obtain classification results with 7 classes by using
Visual Studio program 2017. Based on the research that has been classified with 7 classes, it has the highest
accuracy of 70.18% in which the accuracy produced has not been optimal, so then we proposed classification
process using HDA model. It was performed by separating the classification model into some of the best
models including: Normal and Abnormal Classification with the accuracy of 97.10%, Normal Classification
1,2,3 with the accuracy of 100%, Abnormal Classification 4,5+6,7 with the accuracy of 74, 88%, by referring
to Table 3. Class 5+6 was made into one because there were classification difficulties for the Moderate
Dysplasia class and Severe Dysplasia [14]. The final step was to classify class 5 and 6 with the accuracy of
85.443%.
The HDA model highly depends on the model that has been derived from the classification of each
class to be the reference model for making the HDA algorithm. Therefore, each of the best features that have
been selected by using GA is presented in Table 3 as a representation of HDA model formation. Each class
has a different Hidden layer depending on the number of features selected and the most relevant feature to the
accuracy value.
HDA algorithm model not only affects the accuracy of each class but also affects the weight value
of each node where nodes are obtained from each attribute that has been selected. Each weight has different
values.
Table 3. Selected Attributes Using GA
No Normal and abnormal
Classification Classification 1,2,3
Classification of Class 4, 5, 6, 7
Class 5, 6
1 Kerne_Ycol Kerne_A Cyto_A Kerne_A 2 Cyto_Ycol Cyto_A K/C Kerne_Ycol
3 KerneShort Kerne_Ycol Cyto_Ycol Cyto_Ycol
4 KerneLong Cyto_Ycol KerneLong KerneShort 5 CytoLong CytoElong KerneMax KerneLong
6 CytoRund CytoRund KerneMin CytoShort 7 CytoPeri CytoPeri CytoMax CytoLong 8 KernePos KernePos CytoRund
9 KerneMax CytoMin KernePeri 10 KerneMin CytoPeri 11 KerneMax
12 CytoMax
13 CytoMin
4.1. Application Development of Hierarchy Model
From the results obtained, then the best model was implemented in Visual Studio .Net 2017
application for the classification of 7 classes. The modeling stage used the Visual Studio .Net 2017
application with interface display in Figure 2(a) using each attribute input and 2(b) interface views for
classification using datasets with multiple inputs.
The next step was the classification modeling implementation of 7 classes with the following stages:
normal and abnormal classification model, normal classification model 1, 2, 3, abnormal classification model
4, 5 and 6, 7, and classification of class 5 and 6 with the following explanation: At this stage, the modeling
for the normal and abnormal classification was performed by using the procedure described in the following
stages of the program.
Int J Elec & Comp Eng ISSN: 2088-8708 5421
Improving Hierarchical Decision Approach for Single Image Classification of Pap Smear (Dwiza Riana)
(a)
(b)
Figure 2. Application interface of the classification of 7 classes
Normal and abnormal classification algorithm
Input : Hidden layer Weight of each attribute, Max and Min Weight of each attribute,
Output Weight of each attribute.
Output : Classification dataset of Normal and Abnormal Pap smear image.
Process :
a. Start. Attribute normalization. Normalization=((data-min)/(max-min))*(1-(-1))+(-1); Perform
normalization on each attribute* Minimum and maximum value on training attribute.
b. Calculate the weight of each hidden layer/node with as much weight as the hidden layer in the normal
and abnormal classification model. Begin by calculating each hidden layer obtained from the
multiplication of attributes that have been normalized with each weight that has been determined in
selected attributes using GA.
Furthermore, calculate the weight of each attribute on normal and abnormal class from the calculation
of the initial weight. Calculate the output weights of each Normal and Abnormal Class output value.
Node 1=(normaisasi_attribute * attribute weight)+bias
Node Weight 1=1/(1+Exp (-node1))
c. Calculate the weights of each normal and abnormal classification.
Calculate each classification weight obtained from the multiplication of each weight of the hidden layer
with the weight of the nodes specified in calculation weight of hidden layer. Hidden layers are obtained
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from the multiplication of attributes that have been normalized with each weight that has been
determined in selected attributes using GA.
Classification=(hidden_layer_weights * node weight)+threshold
Classification weight=1/(1+Exp (-classification))
d. Compare the classification weight that has been calculated with the normal and abonormal weight. If
the normal weight is greater than the abnormal weight, the classification results are normal, but
otherwise the classification becomes abnormal.
Classification=if normal weight>abnormal weight
Result=normal
If not
Result=abnormal
e. In the next stage, perform the same process from stage a-d by performing calculations in each
classification including: normal class calssification 1,2,3, Abnormal class 4, 5 and 6, 7 and abnormal
class 5 and 6.
4.2. Comparison Results of Accuracy Values
Table 4 shows that the HDA model has a superior accuracy value compared to the classification
algorithm result shown in Table 4. The results obtained from the research shows that the classification model
of HDA and NN algorithm has superior accuracy compared to other classification algorithms. After doing the
research, the classification results of 4 classes that became the main goal were compared to see which
algorithm and which method is best for the classification into 7 classes.
Based on the test that has been obtained on the Pap smear image dataset, it is known that the NN
and HDA algorithms have the highest accuracy with the value of 87.02% when compared with other
classification algorithms.
Table 4. Comparison of Accuracy Values Algorithm Accuracy
Proposed Method 87,02%
Decision Tree + HDA [14] 83,26 GA + HDA Non Optimized NN [19] 79,78%
Hybrid Ensemble Learning [22] 78,00%
GF + Bagging + Naïve Bayes [24] 63,25% GA + LDA [23] 62,92%
GA + Naïve Bayes [23] 62,16
5. CONCLUSION
Pap smear image classification by using HDA method with the classification test into 7 classes
(normal superficial, normal intermediate, normal colummar, mild (light) dyplasia, moderate dyplasia, servere
dyplasia and carcinoma in situ) has the highest accuracy value of 87.02%. The results obtained from the
HDA model for Pap smear image classification into 7 classes were compared to the classification results
using the NN algorithm and feature optimization using GA to improve accuracy. In this work we propose a
classification methodology in a single cell Pap smear image. This task is particularly useful for normal and
abnormal cell image classification in each class. We can come out with the fact that the proposed method has
not reached a very high level of accuracy. However, we need a more practical, practical alternative method to
classify Pap smear images more accurately. As future work, we intend to expand our method using hybrid
modeling classification. In hopes it can further improve the accuracy achieved. Thus, from the results of our
model testing, it can be concluded that the HDA method for Pap smear image classification can be used as a
reference for initial screening process to analyze Pap smear image classification. Further research will be
done by making web-based applications, and the performance measurement of web-based applications will
be conducted by users who are pathologists and researchers in the field of cervical cancer.
ACKNOWLEDGEMENTS
Authors would like to thank RISTEKDIKTI. This research was supported by The Ministry of
Research, Technology, and Higher Education, Indonesia, for supporting this research through The Pasca
Doctoral Research Grant (2017). This work is using the data from: Pap smear Benchmark Data for Pattern
Classification J. Jantzen, J. Norup, G. Dounias, and B. Bjerregaard, University Dept. of Pathology Herlev
Ringvej 75, DK-2730 Herlev, Denmark.
Int J Elec & Comp Eng ISSN: 2088-8708 5423
Improving Hierarchical Decision Approach for Single Image Classification of Pap Smear (Dwiza Riana)
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BIOGRAPHIES OF AUTHORS
Dwiza Riana was born in Indonesia in 1970. She is a associate professor in STMIK Nusa Mandiri
Jakarta and principal of the Magister Ilmu Komputer at STMIK Nusa Mandiri. She did her BA in
Mathematic at the University of Sriwijaya, Indonesia, Magister of Management at University of
Budi Luhur, Indonesia, Magister of Computer Science at University of Indonesia and PhD in
Electronical Engineering in Informatics at Institut Teknologi Bandung, Indonesia. Her research in
the area of Computer Science, Biomedical Engineering, Data Mining, and Information System.
Yudi Ramdhani was born in Indonesia in 1990. He did her BA in Information Technical at the
University BSI, Indonesia, Magister of Computer Science at STMIK Nusa Mandiri Jakarta,
Indonesia. Her research in the area of Computer Science, Biomedical Engineering, Information
System, and Big Data Analysis.
Rizki Tri Prasetio was born in Indonesia in 1989. He is a Lecturer in Universitas BSI. He did his
Bachelor of Science in Information System at Universitas BSI, Indonesia and Magister of
Computer Science in STMIK Nusa Mandiri Jakarta, Indonesia. His research in the area of Software
Engineering, Big Data and Data Mining, and Mobile Computing.
Achmad Nizar Hidayanto is the Vice Dean for Resources, Ventures, and General Administration,
Faculty of Computer Science, Universitas Indonesia. He received his PhD in Computer Science
from Universitas Indonesia. His research interests are related to information management, IT
diffusion and adoption, e-commerce, e-government, information systems security, change
management, knowledge management and information retrieval.
Improving Hierarchical
Decision Approach for
Single Image Classification
of Pap Smear
by Dwiza Riana
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Improve Hierarchical Decision Approach for Single Image
Classification of Pap Smear
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