2-virus-091010222318-phpapp01

7/21/2019 2-virus-091010222318-phpapp01

1/66

1. PENDAHULUAN

2. PENGGOLONGAN MIKROORGANISME

3. STRUKTUR DAN FUNGSI SEL MIKROORGANISME4. PERTUMBUHAN MIKROORGANISME

5. GENETIKA MIKROORGANISME

6. BIOENERGETIKA MIKROORGANISME

7. PENGENDALIAN PERTUMBUHAN MIKROORGANISME8. INTERAKSI DAN PENYEBARAN MIKROORGANISME

9. PERANAN MIKROORGANISME

POKOK BAHASAN

MIKROBIOLOGIMIKROBIOLOGIDASARDASAR

7/21/2019 2-virus-091010222318-phpapp01

2/66

I. PENDAHULUAN

II. EVOLUSI DAN KERAGAMAN MIKROBA

III. TINGKATAN TAKSONOMI

IV. SISTEM KLASIFIKASI

V. KARAKTERISTIK UTAMA YANG DIGUNAKAN DALAMTAKSONOMI

VI. PERKIRAAN ASSESSING) FILOGENI MIKROBA

VII. DIVISI UTAMA ORGANISME

VIII. BERGEY!S MANUAL OF SYSTEMATI" BA"TERIOLOGY

I#. GARIS BESAR FILOGENI DAN KERAGAMAN PROKARIOT

#. MENGENAL LEBIH DEKAT ANGGOTA DUNIA MIKROBA

POKOK BAHASAN

$2. PENGGOLONGAN MIKROORGANISME
http://www.gbwebdesign.com/index.html

7/21/2019 2-virus-091010222318-phpapp01

3/66

A. AR"HAEA

B. BA"TERIA

". FUNGI

D. ALGAE

E. PROTO%OA

F. VIRUS



POKOK BAHASAN

7/21/2019 2-virus-091010222318-phpapp01

4/66

1. EARLY DEVELOPMENT OF VIROLOGY

2. GENERAL PROPERTIES OF VIRUSES

3. THE "ULTIVATION OF VIRUSES

4. VIRUS PURIFI"ATION AND ASSAYS

5. THE STRU"TURE OF VIRUSES

6. PRIN"IPLES OF VIRUS TA#ONOMY

7. BA"TERIOPHAGES

8. VIRUSES OF EU"ARYOTES


POKOK BAHASAN

F. VIRUS


7/21/2019 2-virus-091010222318-phpapp01

5/66



F. VIRUS#. MENGENAL LEBIH DEKAT ANGGOTA DUNIA MIKROBA

E&'()& *+,,+)-E&'()& *+,,+)-

/0+& (+ )+) /+/ (+ )+:+, &+(+/0+& (+ )+) /+/ (+ )+:+, &+(+

(;< 0= :(,(,(;< 0= :(,(,

++ (+ '+)+ (&+ +:+, /> *+,,+) && , ?,' (++ (+ '+)+ (&+ +:+, /> *+,,+) && , ?,' (

+ +>( (>+, + &+(+ '( ( :)/+ +>( (>+, + &+(+ '( ( :)/

D) I:(,'?D) I:(,'?

&+,)(+& ( (/(:+ (>+, 0( ( &+(+&+,)(+& ( (/(:+ (>+, 0( ( &+(+

(+& )/> 0(+)( +)(+& )/> 0(+)( +)

/> (>+, '( ;,/> (>+, '( ;,

1798

1892

M(,= +&+ :)( &+(+ /))+& 0+)+ (,=,+ /,&+)& + ,(/)+ + (/(:+ (>+, + &+(+
http://www.personal.psu.edu/faculty/j/e/jel5/micro/smallpx.jpg

7/21/2019 2-virus-091010222318-phpapp01

6/66




M(),/ B+@+),?M(),/ B+@+),? '+& ( (/(:+ (>+, 0('+& ( (/(:+ (>+, 0(

( &+(+ '( ,+/ (+)( &+(+ '( ,+/ (+)

)(,)(,

)++))+& (>+, ( +)(0+ :)/)++))+& (>+, ( +)(0+ :)/

L++) (,& F)L++) (,& F)

'+& ( (,&/ &+(+ , (+'+& ( (,&/ &+(+ , (+

'( (/+& 0= +)(0+ :)/'( (/+& 0= +)(0+ :)/

189819$$

189819$$

7/21/2019 2-virus-091010222318-phpapp01

7/66

1. EARLY DEVELOPMENT OF VIROLOGY lanjutanE+)(, (,& B(,>

+ )+ :)/+ , (/,> (>,(,+ '( +(0+&+ )+ :)/+ , (/,> (>,(,+ '( +(0+&

+/?+( , ?+, '( (/+& 0= ( +)(0+ :)/+/?+( , ?+, '( (/+& 0= ( +)(0+ :)/

P+=, R/P+=, R/

'+& ( /+ /) , ?+, '+)+ (/+& 0= ( +)(0+ :)/'+& ( /+ /) , ?+, '+)+ (/+& 0= ( +)(0+ :)/

F)+&+)? T')F)+&+)? T')

+ +;+,+ 0(+)( :)/+ '( +(0+&+ +;+,+ 0(+)( :)/+ '( +(0+&

) (+& 0(+)( :)/+) (+& 0(+)( :)/+

F+; &H+)++F+; &H+)++

' &+:+& ( +& ) +,/+)(,> +' &+:+& ( +& ) +,/+)(,> +

&+,)(+& ( += /& )+)&/+ ,= , :+ 0(+)(&+,)(+& ( += /& )+)&/+ ,= , :+ 0(+)(

19$8

1911

1915

1917
http://en.wikipedia.org/wiki/Image:Twort.jpg

7/21/2019 2-virus-091010222318-phpapp01

8/66

1. EARLY DEVELOPMENT OF VIROLOGY lanjutan

7/21/2019 2-virus-091010222318-phpapp01

9/66


2. GENERAL PROPERTIES OF VIRUSES

3. THE "ULTIVATION OF VIRUSES


5. THE STRU"TURE OF VIRUSES


7. THE BA"TERIAL VIRUSES BA"TERIOPHAGES> +)+& ?+, +>> ,/0(+& (0/ 68 &(=(+) (=,> F>/)+ 16.1 + 0) //)+

//(= +() '+ (/+ ) , (>() //)+ F>/)+ 16.4(, :)/ ()+

D+)+,( +,)/>(, +()(+ ()&,> + F>/)+ 16.6(, +()(+ ()&,> &+,= ) +&+,(,

)(+ + (,& &+,==

+()(+ :)/+ ) +) ,+, + ;/)+

. D+,(/)(, (,& )+(, ,(,(, ' +( H ) +:+,)>(, :+, (, ++ 0+ /+&

:. E,=( &+>)(&(, +/() )+, (,&) ,/+ (& (,

++ 0+ /+& 0+(/+ :)/+ +,& 0+ )+ )+(, ++

=+ )+(+,

7/21/2019 2-virus-091010222318-phpapp01

17/66


$2. PENGGOLONGAN MIKROORGANISMEF. VIRUS#. MENGENAL LEBIH DEKAT ANGGOTA DUNIA MIKROBA

0. V)/ ((=

. P()+ /,

D)+ /, (, 0+ (&+ ' (, ++), )+ F>/)+ 16.8 +& / ( +(>>/,(, :)/

()+ (, (/+ )+& 0& + / >++) ) (>>/,(+< F>/)+33.9 &/, :)/ ()+ , ( (',

+ +() ,+ )+/ ) :)( &((>+ + + )+/ ()+ +;)++&( (/+),> /, PFU + (+

(/, :)/ ,++&+& (/+ ( +(/)(0+ ++ //(= , 5$ +

+;+& ()>+ /, )+/ ()+ +;)++& ( ,+/ &+ ID5$< )

+( &+ LD5$< F>/)+ 16.9+ ) 1$ , 4$$ , F>/)+ 16.1$ (& )+, ( (

/))/,& + >+,++,+ 0= ( )+ (+& +(+0=

7/21/2019 2-virus-091010222318-phpapp01

20/66


5. THE STRU"TURE OF VIRUSES LAN*UTAN/() (+

(,& 12 :+)+ (+() +)( ,)/+& (+)+ ),> )

?,0(+& /,/)+ 16.12 >=)+, ?+ ++)+. V)/+ ' (& +; =+)=

. P;:)/+ ()+ ()>+ 2$$ 4$$ ,< ' (, :& +;+)) (+

. S+ 0(+)(>+ (:+ +; +(0)(+ (+ +& +(&

(+&)( =+)=< /+& ( +( =+)=, ()+ ()/()= :()(0+ / :)/+ ()+ (& (:+ 0,(

=+)= F>/)+ 16.19 , ++ )+)+-

. N/+ (& =+

. N/+ (& )(,&+&,+ &/0+ ) ,>+ )(,&+&+,+

:. T+ )++,+ ) (0+,+ (, +,:++

:. T+

7/21/2019 2-virus-091010222318-phpapp01

25/66



0. I, (&&, +) ()(+) (, 0+ ,&+)+&-. "APSID SYMMETRY

. DIAMETER OF "APSID OR NU"LEO"APSID

. NUMBER OF "APSOMERES IN I"OSAHEDRAL VIRUSES

:. IMMUNOLOGI"AL PROPERTIES

:. GENE NUMBER AND GENOMI" MAP

:. INTRA"ELLULAR LO"ATION OF VIRUS REPLI"ATION

:. PRESEN"E OR ABSEN"E OF A DNA INTERMEDIATE IN THEREPLI"ATION OF RNA VIRUSES

:. TYPE OF VIRUS RELEASE

;. DISEASE "AUSED BY THE VIRUS

7/21/2019 2-virus-091010222318-phpapp01

26/66

"(+) C+0 L,?A + V)>= , + CCC

(http://www.tulane.edu/~dmsander/garryfavweb.html)All the Virology on the WWW "seeks to be the best single site for Virology information on the Internet. We have

collected all the virology related Web sites that might be of interest to our fellow virologists, and others interestedin learning more about viruses".

T+ B> P/)+ B? V)/+

(http://www.tulane.edu/~dmsander/Big_Virology/BVFamilyenome.html)

The Big icture Book of Viruses is "intended to serve as both a catalog of virus !ictures on the WWW and as an

educational resource to those seeking more information about viruses".

E+), ) (>+ H/(, V)/+

http://www.u!t.a!."a/depts/mmi/stannard/linda.html)#lectron microso!ic images of $uman Viruses % &inda 'tannard(s "illustrated tutorial on the mor!hology of most

of the clinically significant viruses. The section on $e!atitis B virus is es!ecially recommended".

V/((, V)/+ ( + U,:+)= C,, M(&,

(http://www.bo!#labs.wis!.edu/virusvi"top.html)

T+ I,&+; V)/

(http://life.anu.edu.au/viruses/$!tv/inde%.html)The Inde) Virum !resents lists of virus ta)a that reflect the currently a!!roved classification of the International

*ommittee on Ta)onomy of Viruses I*TV+.
http://all%20the%20virology%20on%20the%20www.htm/http://the%20big%20picture%20book%20of%20viruses.htm/http://electron%20microsopic%20images%20of%20human%20viruses.htm/http://www.bocklabs.wisc.edu/virusviztop.htmlhttp://the%20index%20virum.htm/http://the%20index%20virum.htm/http://www.bocklabs.wisc.edu/virusviztop.htmlhttp://electron%20microsopic%20images%20of%20human%20viruses.htm/http://the%20big%20picture%20book%20of%20viruses.htm/http://all%20the%20virology%20on%20the%20www.htm/

7/21/2019 2-virus-091010222318-phpapp01

27/66

7. THE BA"TERIAL VIRUSES BA"TERIOPHAGES="(& )>=--

H+(H+(- )+, )( +0+,/? )( &+?+,>- )+, )( +0+,/? )( &+?+,>

(( ,/?+(. D(( ?(?/ ((/ +?0+.(( ,/?+(. D(( ?(?/ ((/ +?0+.T0( ( :)/T0( ( :)/

E0( :)/E0( :)/

P=+&)(P=+&)(- 0(,=(? . B+,/? // (&((- 0(,=(? . B+,/? // (&(((+&),(+&), &+,>(, 2$ /?( +>>( &(, 12 /&/ &+,>(, 2$ /?( +>>( &(, 12 /&/P:)/P:)/

H+)+:)/H+)+:)/

"+; :)/+"+; :)/+- 0+,/? &(? +)(/) //+ +/,=( +)(0/ +0()(, &(, ( =(,>B(+)(>+ +/,=( +)(0/ +0()(, &(, ( =(,>

+)?( (&+)?( (&

P;:)/+ +/,=( 0+0+)(( +/0/,> +0/,>?/ ((P;:)/+ +/,=( 0+0+)(( +/0/,> +0/,>?/ ((

,/?+(.,/?+(.

$2. PENGGOLONGAN MIKROORGANISMEF VIRUS

7/21/2019 2-virus-091010222318-phpapp01

50/66


3. STRUKTUR VIRUS

7/21/2019 2-virus-091010222318-phpapp01

51/66

V)/ +0 ?+ &0(,&,>?(, +0(>(, 0+() +V)/ +0 ?+ &0(,&,>?(, +0(>(, 0+() +

7/21/2019 2-virus-091010222318-phpapp01

52/66

micro.magnet.fsu.edu/ cells/virus.html AKSES 30/03/06

V)/ +0 ?+ &0(,&,>?(, +0(>(, 0+() +V)/ +0 ?+ &0(,&,>?(, +0(>(, 0+() +

B Vi l St tB Vi l St t

7/21/2019 2-virus-091010222318-phpapp01

53/66

B. Viral StructureB. Viral Structure

1.1. Genome:Genome:

2.2. Capsid/CapsomerersCapsid/Capsomerers

3.3. EnelopesEnelopes

!i"ure 1#.2 Viral structure!i"ure 1#.2 Viral structure

7/21/2019 2-virus-091010222318-phpapp01

54/66

7/21/2019 2-virus-091010222318-phpapp01

55/66

!i"ure 1#.02$1 Adenoirus!i"ure 1#.02$1 Adenoirus

7/21/2019 2-virus-091010222318-phpapp01

56/66

7/21/2019 2-virus-091010222318-phpapp01

57/66

DNA /,( /,>>( DNA>( DNA(,&( &DNA(,&( &DNA( RNA>( RNA

7/21/2019 2-virus-091010222318-phpapp01

58/66

HOST RANGE- SPE"TRUM OF HOSTS A VIRUS "AN INFE"THOST RANGE- SPE"TRUM OF HOSTS A VIRUS "AN INFE"T

7/21/2019 2-virus-091010222318-phpapp01

59/66

B(+)(B(+)(

A,(A,(

P(,P(,

F/,>F/,>

P)P)

HOST RANGE- SPE"TRUM OF HOSTS A VIRUS "AN INFE"T.HOST RANGE- SPE"TRUM OF HOSTS A VIRUS "AN INFE"T.

VIRAL SPE"IFI"ITY- TYPES OF "ELLS THAT VIRUS "AN INFE"T.VIRAL SPE"IFI"ITY- TYPES OF "ELLS THAT VIRUS "AN INFE"T. D+))D+))

N+/))N+/))

P,+/)P,+/)

L=)L=)

V+))- L:+) +() ++, +.V+))- L:+) +() ++, +.

Lsogenic versus Ltic !cles ofLsogenic versus Ltic !cles of

7/21/2019 2-virus-091010222318-phpapp01

60/66

g g

Bacterio"hageBacterio"hage

7/21/2019 2-virus-091010222318-phpapp01

61/66

7/21/2019 2-virus-091010222318-phpapp01

62/66

Life !cle #a"ovirus $ %irusLife !cle #a"ovirus $ %irus

7/21/2019 2-virus-091010222318-phpapp01

63/66

Life !cle #a"ovirus $ %irusLife !cle #a"ovirus $ %irus

D&A'D&A'

R " RNA DNA R T R+) ) + ", +) RNA , DNA ( R+ +)+ T)(,)(+

7/21/2019 2-virus-091010222318-phpapp01

64/66

R+):)/+ ",:+) RNA , DNA :( R+:+)+ T)(,)(+R+):)/+ ",:+) RNA , DNA :( R+:+)+ T)(,)(+

Structure of In(uen)aStructure of In(uen)a

7/21/2019 2-virus-091010222318-phpapp01

65/66

Structure of In(uen)aStructure of In(uen)a

%irus%irus

7/21/2019 2-virus-091010222318-phpapp01

66/66

Viruses and CancerViruses and Cancer

1. Cancer results from the uncontrolled reproduction of cells2. Certain chemicals are known to be carcinoges or cancer-causing substances

3. Evidence that viruses are carcinogenic

4. Example herpesviruses associated with tumors of the human cervix

!. Cancer development the oncogene theor"

2-virus-091010222318-phpapp01

Documents