Reactions 436 - 30 Jan 1993

Triazolam/temazepam

Behavioural disturbances: incidence studyA review of the records at McLean Hospital,

Massachussetts, USA, revealed no significant differencebetween the incidence of behavioural disturbances inpsychiatric inpatients who received triazolam (n = 72) ortemazepam (112).

Author comment: ‘We did not find that triazolam hadunique disinhibitory activity.’ Editorial Comment: The resultsof a survey published recently in the Lancet showed thatagents given as substitutes for triazolam following thewithdrawal of the latter were not necessarily associated withfewer adverse effects (see Reactions 435: 2, 23 Jan 1992)Rothschild AJ, et al. Triazolam and disinhibition. Lancet 341: 186, 16 Jan 1993 -USA 800176681

» Editorial comment: The results of a survey published recentlyin the Lancet showed that agents given as substitutes fortriazolam following the withdrawal of the latter were notnecessarily associated with fewer adverse effects [see Reactions435: 2, 23 Jan 1992].

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Reactions 30 Jan 1993 No. 4360114-9954/10/0436-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved