Reactions 1396 - 7 Apr 2012

Teriparatide

Hypercalcaemia: case reportA 20-year-old man with progeroid syndrome presented

with severe osteoporosis, and received weekly alendronicacid, calcium and vitamin D supplements. Eight monthslater, treatment was discontinued due to diarrhoea. Afterdeveloping a subcapital femoral fracture 6 months later, hestarted receiving SC teriparatide 20µg daily for 18 months.Within 1 month of starting teriparatide, he developedasymptomatic hypercalcaemia (10.7 mg/dL). Changes tohis treatment were not required, and 3 months aftercompleting teriparatide, his serum calcium levels hadreturned to normal.Iglesias Bolanos P, et al. Complicated Osteoporosis in Progeroid Syndrome:Treatment With Teriparatide. Journal of Clinical Densitometry 15: 116-119, No. 1,Jan-Mar 2012. Available from: URL: http://dx.doi.org/10.1016/j.jocd.2011.10.001 -Spain 803068951

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Reactions 7 Apr 2012 No. 13960114-9954/10/1396-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved