herbal medicine knowledge base (hmkb) system

Version: 1.0

Herbal Medicine Knowledge

Base (HMKB) System

Supiah Mustaffa Ros’aleza Zarina Ishak Lee Chee Kiam Michelle Lim Sien Niu Nor Ezam Selan (MIMOS Berhad) Mary Sintoh (SEDIA)

Outline

• Problem Statement

• Knowledge Modeling and Engineering

• Collaborative Knowledge Management

• Value of the Proposition

• Future Works & Conclusion

Problem Statement

Problem:

• deterioration of herbal medicine knowledge

• scattered and unstructured information data sources

Solution:

• compile the information into a standard, reusable format

and store it into a central repository that can be referred by

different stakeholders

Objectives

HMKB is developed to : 1) document and preserve Malaysian herbal

medicine knowledge

2) provide collaborative platform for community of

practice

3) boost economic sector related to herbal medicine

4

Outline






6

6

http://www.sabahinfomed.com.my/TraditionalMedicine/

http://www.sabahinfomed.com.my/Process/ http://www.sabahinfomed.com.my/Herb/

http://www.sabahinfomed.com.my/Pharmacology/

High level architecture of Herbal

Medicine Knowledge Base (HMKB)

Pharmacology

Traditional

Medicine

ProcessHerb

hasProcesshasHerb

hasInputhas

Pharmacology

7

Knowledge Modeling and Engineering

Describe the knowledge about herb include:

-scientific name, family name, origin, distribution location, suitability of

climate, rainfall requirement, soil type, propagation parts and

management information

Pharmacology

Traditional

Medicine

ProcessHerb

Herb

8

Jasminum sambac Soland. Ex Ait.

Arabian jasmine {@en}

Alkoloids

hasSynonymskos:prefLabel

hasChemical

Constituent

Oleaceae

hasFamilyName

India

isOriginatedFrom

China

hasDistributedPlace

Nyctanthes sambac L.

hasNatural

Occurance Forest

hasTemperature

HerbTemperature

has

AnnualRainfall

propagated

By

hasAltitude

Herb

Altitude

Seed

SandyLoamy

Soil

hasSoil

Type

Tropical

hasClimate

hasRequired

Fertilizer

hasDisease

Detail

hasPest

Detail

Nitrogen

JSS

Disease

JSSPest

50

Herb

Annual

Rainfall

hasMinimum

Quantity

hasMeasurement

Unit

40

hasQuantity

hasMeasurement

Unit

800

Meter

hasMinimum

Quantity

hasMeasurement

Unit

25

Celcius

Centimeter

hasMaximum

Quantity

40

hasMaximum

Quantity

LeafSpot

hasDisease

hasDisease

Control Captan

Spray

Apply

Diazinon

Thrips

hasPest

hasPest

Control

<http://www.efloras.org/florataxon.aspx?flora_id=110&ta

xon_id=200017788>

hasImage

Jasminum

Image

hasImageLink

hasFileFormat JPEG

Instance

Datatype property

Annotation property

9


Consolidate important information about the prescription of certain

medicine to cure certain diseases

- required quantity of herbs, the disease cured, detailed prescription and

prescription method

Pharmacology

Traditional

Medicine

ProcessHerb

Traditional Medicine

10

Jasminum

sambacLAit

JSLAFor

Gallstone

usedToTreat

Gallstone

hasPlant

PartUsed

Young Leave

hasMedication

Prescription

JSLAForGallstonePrescription1

JasminumSambacHerbUsed1

hasHerb

hasMeasurementUnit

Gramme

10

hasQuantity

hasQuantity

150

hasMeasurement

Unit

Mililiter

hasFrequency

hasTreatmentMethod

Drink

3 times daily

hasDuration

JSLAForGallstoneDuration

hasProcess

JSLAForGallstoneProcess

has

Traditional

Medicine

hasQuantityhasMeasurement

Unit

3

Week

11


Explains the sequence of interdependent and linked procedures for

traditional medicine preparation

Pharmacology ProcessHerb

Traditional

Medicine

Process

12

JSLAForGallstoneProcess

expandTo

Boil

Water

10 gram of young leaves, 3 cups of water boiled to become 1 cup.

expandTo

Add

Water

herb:hasDescription

Add up to 450 ml hot water for infusion.

followBy

hasInitial

Process

hasInputJasminum sambac Soland. Ex Ait.

herb:hasDescription

13


Consist of pharmacology activity and pharmacology toxicity knowledge

Herb

Traditional

Medicine

ProcessPharmacology

Pharmacology

14

JSLA anti-

stress

chemical

JSLA

Phamacology

Stree

hasProduced

Chemical

hasMeasurement

Unit

Milligram per

kilogram

200

Benzyl acetate

hasPharmacology

protectAgainst

hasQuantity

hasConcentration

UnitIC50

useTestModel

In vitro

hasPharmacology

Activity

Anti-stress hasChemical

Extract

useExtract

JSLA anti-

stress

extract

Microgram

per milliliter200

hasQuantityhasMeasurementUnit

hasConcentration

Unit

Methanol

hasExtract

Type

IC50

extractFrom Stem

Jasminum sambac Soland. Ex Ait.

Outline






Collaborative Knowledge Management

16

Collaborative Knowledge

Management

Navigation

Search

Authoring

Data Validation

Customized tree view

Semantic Data Access

Layer


17


Management

Navigation

Search

Authoring

Data Validation

Customized tree view

Semantic Data Access

Layer

Navigation, Search, Authoring

18

Search

Navigation

Authoring

Data Validation

19


20


Management

Navigation

Search

Authoring

Data Validation

Customized class hierarchy view

Semantic Data Access Layer


• Customized tree view

21

a b

Original tree (a) versus customized tree (b)

Pharmacology

Traditional medicine


22


Management

Navigation

Search

Authoring

Data Validation

Customized class hierarchy view

Semantic Data Access Layer


• Semantic Data Access Layer (DAL)

– Adopted SOA architecture

23

Component

A

Component

B

1

2

3

45

6

10

9

11

7

8Delegator

Lookup

KBInterfaceClient

Authenticator

AllegroGraph

Server 3.2

Cache

KBInterface

MySQL

Server 5.0.84

Lucene

Index

Semantic Technology Platform KBInterface

Triple

Store

Outline






Value Proposition

25

Scalability with SOA architecture

Knowledge enrichment capabilities

Simple approval workflow

Support diagnosis

decision process Drug discovery

Value Proposition

Comparative Study

26

Feature TROPICOS HerbMed HMKB

Free text search √ √ √

Text completion/ suggestion √ X √

Advance search √

Available only for the licensed version of the database. √

Wildcard support √ √ √

Content contribution X X

Subject matter experts are allowed to contribute content

User Guide – User Manual X √ √

Statistic √ X √

Navigation √ √ √

Access Free Subscription fee required Free

Outline

• Motivation/Problem statement





Future Works

1. Deployment stage

2. Impact study

28

Future Works

Internal Pilot Test

• involves the internal users identified within SEDIA department

• involve 20 users

• focus on system familiarization, training and data migration and transition

Controlled deployment

• participation from selected government agencies and organizations

• includes engagement of selected subject matter experts

Full deployment

• Herbal Medicine web portal will be made available for public access to information on pharmacology, herbs and traditional medicine

• the community of practice will be able to contribute their knowledge and inputs in the related fields

29

1. Deployment stage

Future Works

2. Impact Study

Economy

• encourage the cash flow

• promote exploration and production activity

• offer job employment

Socio economy

• reduce time required in collecting and accessing herbal medicine knowledge

• increase awareness among users

• increase usage of herbal medicine among users

• promote commercialization of herbal medicine

30

Economy Socio economy

Encourage the cash flow in herbal medicine industry

Reduce the time required by the practitioners in collecting and accessing herbal medicine knowledge since the system is available anytime, anywhere

Promote exploration and production activity related to herbal medicine in the country

Increase awareness among the users on the use of herbal medicine as compared to modern drug

Offer job employment in herbal medicine production or herbal plantation/ farming to meet the herbal medicine demand

Increase the usage of herbal medicine as alternative medicine among the user.

Promote the commercialization of herbal medicine to fulfill the user’s demand

Conclusion

HMKB System:

• preserve the herbal medicine knowledge

• provide collaborative platform for

community of practice

• promote herbal medicine economic

demands

31

32

QUESTION AND

ANSWER

herbal medicine knowledge base (hmkb) system

Documents