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CURRICULUM VITAE

A. BUTIR-BUTIR PERIBADI (Personal Details)

NamaPenuh(Full

Name) SharidaFakurazi Gelaran(Title):Associate

Professor No. MyKad / No.

Pasport(Mykad No. /

Passport No.)

720714-02-5636

Warganegara(Citizenship)

Malaysian Bangsa(Race)

Malay Jantina(Gender)

Female

Jawatan(Designation)

Associate Professor TarikhLahir(Date

of Birth) 14 July 1972

AlamatSemasa(Current

Address) Jabatan/Fakulti(Department/Faculty) E-meldan URL (E-mail

Address and URL)

Tel:03-89472117

Fax:03-89472118

Department Of Human Anatomy Faculty Of Medicine And Health Sciences, Universiti Putra Malaysia, 43400, UPM Serdang, Serdang, Selangor Malaysia Tel: 03-89472352 Fax: 03-89422341

E-mail: sharida@upm.edu.my sharida.fakurazi@gmail.com URL: H/P: 012-6883800

B. KELAYAKAN AKADEMIK(Academic Qualification)

NamaSijil /

Kelayakan(Certificate /

Qualification obtained)

NamaSekolahInstitusi(Name

of School / Institution) Tahun(Year

obtained) Bidangpengkhusususan (Area of Specialization)

PhD Imperial College School Of Science, Technology And Medicine, South Kensington, London

2001 Biochemical Toxicology

Diploma of Imperial College

Imperial College School Of Science, Technology And Medicine, South Kensington, London

2001 Molecular Toxicology

BSc (Hons) Pharmacology

University Of Dundee 1996 Pharmacology

C. KEMAHIRAN BAHASA (Language Proficiency) Bahasa / Language Lemah

Poor (1)

Sederhana

Moderate (2)

Baik

Good (3)

AmatBaik

Very good (4)

Cemerlang

Excellent (5)

English /

BahasaMelayu /

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D. PENGALAMAN SAINTIFIK DAN PENGKHUSUSAN (Scientific experience and Specialisation) Organization Position Start Date End Date Expertise

Department Of Biochemistry And Molecular Biology, School Of Biomedical Sciences, Faculty Of Medicine, Nursing And Health Sciences, Monash University, Clayton Campus, Victoria, Australia

Visiting Scientist March2009 Sept2009 2D gel electrophoresis and OFF gel system

Imperial College of Science, Technology and Medicine

Research Student/associate

1998 2001 Immunochemical detection and Biochemical analysis- Western Blotting, Immunohistochemical analysis, ELISA

E. PEKERJAAN (Employment) Majikan / Employer Jawatan / Designation Jabatan / Department Tarikhlantikan /

Start Date

Tarikhtamat /

Date Ended

Universiti Putra Malaysia

Associate Professor

Human Anatomy 2008 Now

Universiti Putra Malaysia

Senior Lecturer Human Anatomy 2005 2008

Universiti Putra Malaysia

Lecturer Human Anatomy 2001 2005

Universiti Putra Malaysia

Tutor Biomedical Science

1997 2001

FANUGERAH DAN HADIAH(Honours and Awards) Name of awards

Title Award Authority Award

Type

Year

Awards

Universiti Putra Malaysia Certificate of

Excellent Service

Universiti Putra

Malaysia

2013

Universiti Putra Malaysia Certificate of

Excellent Service

Universiti Putra

Malaysia

2012

Universiti Putra Malaysia Certificate of

Excellent Service

Universiti Putra Malaysia Certificate of

Excellent Service

Universiti Putra Malaysia Certificate of

Excellent Service

Universiti Putra Malaysia Certificate of

Excellent Service (2005)

Universiti Putra

Malaysia

Universiti Putra Malaysia

Universiti Putra Malaysia

Universiti Putra Malaysia

Universiti Putra Malaysia

2011

2010

2008

2006

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Universiti Putra Malaysia Certificate of

Excellent Service (2004)

2005

Certificate of Award – GOLD

Pameran Rekacipta Penyelidikan dan Inovasi,

UPM 2014

“A Moringa oleifera bioactive fraction

enhances wound healing closure in diabetic

animal model”

Research Management

Centre (UPM)

2014

Certificate of Award – SILVER

Pameran Rekacipta Penyelidikan dan Inovasi,

UPM 2014

“Efficient controlled release anti parkinsonian

nanodrug delivery system intercalated with

levodopa”

Research Management

Centre (UPM)

2014

Certificate of Award – SILVER

Pameran Rekacipta Penyelidikan dan Inovasi,

UPM 2014

“Development of hepatoprotective agent from

hydroethanolic fractions of Moringa oleifera,

enhances antioxidant activities of injured

liver”

Research Management

Centre (UPM)

2014

Certificate of Award – BRONZE

Pameran Rekacipta Penyelidikan dan Inovasi,

UPM 2014

“Protocathechuic acid Magnesium/Alumunium

layered double hydroxide nanocomposite as

anticancer drug delivery agent”

Research Management

Centre (UPM)

2014

Certificate of Award – SILVER

Pameran Rekacipta Penyelidikan dan Inovasi,

UPM 2014

“A highly biocompatible antituberculosis

nanodelivery formulation based on para

aminosalicylic acid zinc layered double

hydroxide nanocomposite “

Research Management

Centre (UPM)

2014

Certificate of Award – SILVER

Pameran Rekacipta Penyelidikan dan Inovasi,

UPM 2014

“Magnetite nanopartciles coated with 6-

mercaptopurine as an anticancer drug delivery

system “

Research Management

Centre (UPM)

2014

Certificate of Award –

“Silver”sempenaPameranRekaciptadanPenyeli

dikan, UPM 2005

“Biocompatibility of Biomaterial in Bone

Tissue Engineering”

Malaysia Toray Science Foundation (MTSF

2003) Science and Technology Research Grant

Award

Certificate of Award –

“Gold”sempenaPameranRekaciptadanPenyelid

Research Management

Centre (UPM) and

Institute Bioscience (IBS)

Malaysia Toray Science

Foundation (MTSF)

Research Management

Centre (UPM) and

Institute Bioscience

(UPM)

2005

2004

2004

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ikan, IBS 2004;

Strobilanthesscrispus Tea: is not just a drink

Certificate of Award –

“Silver”sempenaPameranRekaciptadanPenyeli

dikan, IBS 2004:

Phenotyping of tissue engineered skin-

bringing hope to patients with severe skin

wound

Certificate of Award – “Bronze”

sempenaPameranRekaciptadanPenyelidikan,

IBS 2004-

Liver Histological Analysis Following Hepar

P pretreatment prior to challenge with

paracetamol

Travel Award (UPM) 2004- attend Yemeni

Scientific Research Foundation Conference,

Sanaa, YEMENI, 2004

Universiti Putra Malaysia Certificate of

Excellent Service (2002)

Travel Award (UPM)- attend The International

Symposium on Free Radicals and Health:

Molecular Interventions and Protection of

Life-Styled Related Diseases 2003, JAPAN

Certificate of Award – “Silver”

sempenaPameranRekaciptadanPenyelidikan

2003

Microsatelliting of Antioxidant Elements

During Hepatocarcinogenesis Treated with

Strobilanthescrispus

Certificate of Award – “Bronze”

sempenaPameranRekaciptadanPenyelidikan

2003

The effect of multiple doses of

Zingiberzerumbet on Liver of Male Sprague-

Dawley rats

Certificate of Award – “Bronze”

sempenaPameranRekaciptadanPenyelidikan

2003

The effect of multiple doses of

Zingiberzerumbet on Liver of Male Sprague-

Dawley rats

Travel Award (UPM)- attend 2nd

International

Symposium on Antioxidants in Nutrition &

Therapy, 2002, INDONESIA, Mechanisms in

Physiology-Pathology-Pharmacology,

Certificate of Award – “Silver”

sempenaPameranRekaciptadanPenyelidikan

2002

Taurine and creatine excretion following

benoxaprofen administration in male Sprague-

Research Management

Centre (UPM) and

Institute Bioscience

(UPM)

Research Management

Centre (UPM) and

Institute Bioscience

(UPM)

Universiti Putra Malaysia

Universiti Putra Malaysia

Universiti Putra Malaysia

Research Management

Centre, Universiti Putra

Malaysia

Faculty of Medicine and

Health Sciences,

Universiti Putra Malaysia

Universiti Putra Malaysia

Universiti Putra Malaysia

Research Management

Centre, Universiti Putra

Malaysia

International Society for

the Study of Xenobiotics

(ISSX)

2004

2004

2004

2003

2003

2003

2003

2003

2002

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Dawley rats

Travel Award (ISSX)

Travel Award (BTS)

British Toxicological

Society (BTS)

2002

2000

Awards of

Merit

Best Publication Award

Development of a controlled release anti

parkinsonian nanodelivery system using

levodopa as the active agent

2014

G. SENARAI PENERBITAN (Sila masukan namapengarang, tajuk, namajurnal, jilid, mukasurat dan tahun diterbitkan)(List of publications – author (s), title, journal, volume, page and year published)

No List of publications Impact factor IF

1. Mohamad Taufik Hidayat Bin Baharuldin,Abdul Manan Mat Jais,Mohamad Aris Mohd Moklas,Sharida Fakurazi, (2016) Antidepressant-like effect of lipid extract of Channa striatus in chronic unpredictable mild stress model of depression in rats, Evidence-Based Complementary and Alternative Medicine, Article ID 2986090, 17 pages

2. Latifah Saiful Yazan,Sharida Fakurazi, Induction of apoptosis and G2/M arrest by ampelopsin E from Dryobalanops towards triple negative breast cancer cells, MDA-MB-231, (2016) BMC Complementary and Alternative Medicine, BMC, 354

3. Mohd. Zobir Bin Hussein,Sharida Fakurazi, Graphene Oxide-Gallic Acid Nanodelivery System for Cancer Therapy, (2016) Nanoscale Research Letters vol 11:491

4. Mohd. Zobir Bin Hussein,Sharida Fakurazi, (2016) In vitro drug release characteristic and cytotoxic activity of silibinin-loaded single walled carbon nanotubes functionalized with biocompatible polymers, Chemistry Central Journal, 10:81

5. Mohd. Zobir Bin Hussein,Sharida Fakurazi, Biocompatible polymers coated on carboxylated nanotubes functionalized with betulinic acid for effective drug delivery, Journal of Materials Science: Materials in Medicine, 27:26

6. Sharida Fakurazi,Norhaszalina Binti Md. Isa, The modulatory effect of moringa oleifera leaf extract on endogenous antioxidant systems and inflammatory markers in acetaminophen induced nephrotoxic mice model, PeerJ preprint,

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7. Sharida Fakurazi,Faridah Abas,Cheah Pike See, Evaluation of wound healing properties of bioactive aqueous fraction from Moringa oleifera Lam on experimentally induced diabetic animal model, Drug Des Devel Ther.vol 10: 1715–1730.

8. Mohd. Zobir Bin Hussein,Sharida Fakurazi,Zurina Zainal Abidin, The In Vitro Therapeutic Activity of Ellagic Acid-Alginate-Silver Nanoparticles on Breast Cancer Cells (MCF-7) and Normal Fibroblast Cells (3T3), : Science of Advanced Materials, Volume 8, Number 3, pp. 545-553(9)

9. Mohd. Zobir Bin Hussein,Sharida Fakurazi, Synthesis, characterization, and efficacy of anti-tuberculosis isoniazid zinc aluminium-layered double hydroxide based nanocomposites, Int J Nanomedicine. vol 11: 3225–3237

10. Sharida Fakurazi,Faridah Abas,Mas Jaffri Masarudin, Optimization, formulation, and characterization of multi avonoids-loaded flavanosome by bulk or sequential technique, Int J Nanomedicine. vol 11: 3417–3434.

11. Mohd. Zobir Bin Hussein,Sharida Fakurazi, Synthesis, characterization, and efficacy of anti-tuberculosis isoniazid zinc aluminium-layered double hydroxide based nanocomposites, Int J Nanomedicine. vol 11: 3225–3237

12. Sharida Fakurazi,Norhaszalina Binti Md. Isa, The modulatory effect of moringa oleifera leaf extract on endogenous antioxidant systems and inflammatory markers in acetaminophen induced nephrotoxic mice model, peerJ preprint,

13. Mohamad Taufik Hidayat Bin Baharuldin,Rusliza Basir,Abdul Manan Mat Jais,Mohamad Aris Mohd Moklas,Sharida Fakurazi, Involvement of monoaminergic system in the antidepressant-like effect of channa striatus extracts in mice

14. Mohd. Zobir Bin Hussein,Sharida Fakurazi, Release behaviour and toxicity evaluation of levodopa from carboxylated single-walled carbon nanotubes, Beilstein J. Nanotechnol. 2015, vol 6, 243–253.

15. Sharida Fakurazi,Faridah Abas,Mas Jaffri Masarudin, Optimization, formulation, and characterization of multi avonoids-loaded flavanosome by bulk or sequential technique, Int J Nanomedicine. ; vol11: 3417–3434.

16. Chen Hui Cheng,Sharida Fakurazi,Goh Yong Meng, Serum concentration of ketamine and antinociceptive effects of ketamine and kBMC Veterinary Researchvetamine-lidocaine infusions in conscious dogs, BMC Veterinary ResearchBMC series – open, inclusive and trusted,vol 12:198.

17. YA Rahaman, SK Yeap, SW Tan, M Hair-Bejo, S Fakurazi, P Kaiser, AR Omar (2015) In vitro characterization of chicken bone marrow-derived dendritic cells following infection with very virulent infectious bursal disease virus, Avian Pathology, 1-41

18. G Karthivashan, P Arulselvan, SW Tan, S Fakurazi (2015) The molecular mechanism underlying the hepatoprotective potential of Moringa oleifera leaves extract against acetaminophen induced hepatotoxicity in mice, Journal of Functional Foods 17, 115-126

3.58

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19. Ubedullah Kaka, Hui Cheng Chen, Yong Meng Goh, Adamu Abdul Abubakar, Sharida Fakurazi, Mahdi Ebrahimi (2015) Validation of a Modified Algometer to Measure Mechanical Nociceptive Thresholds in Awake Dogs, BioMed Research International, Volume 2015, Article ID 375421, 7 pages

1.579

20. AU Kura, B Saifullah, PS Cheah, MZ Hussein, N Azmi, S Fakurazi (2015) Acute oral toxicity and biodistribution study of zinc-aluminium-levodopa nanocomposite, Nanoscale Research Letters 10 (1), 1-11

2.78

21. Ubedullah Kaka, Chen Hui Cheng, Goh Yong Meng, Sharida Fakurazi, Asmatullah Kaka, Atique Ahmed Behan, Mahdi Ebrahimi (2015) Electroencephalographic changes associated with antinociceptive actions of lidocaine, ketamine, meloxicam, and morphine administration in minimally anaesthetized dogs, BioMed Research International, Volume 2015, Article ID 305367, 10 pages ttp://dx.doi.org/10.1155/2015/305367

1.579

22. PNA Syarina, G Karthivashan, F Abas, P Arulselvan, S Fakurazi (2015) Wound healing potential of Spirulina platensis extracts on human dermal fibroblast cells, EXCLI Journal 2015;14:385-393.

0.728

23. JM Tan, JB Foo, S Fakurazi, MZ Hussein (2015) Release behaviour and toxicity evaluation of levodopa from carboxylated single-walled carbon nanotubes, Beilstein Journal of Nanotechnology 6 (1), 243-253

2.67

24. M Adewoyin, SMN Mohsin, P Arulselvan, MZ Hussein, S Fakurazi (2015) Enhanced anti-inflammatory potential of cinnamate-zinc layered hydroxide in lipopolysaccharide-stimulated RAW 264.7 macrophages Drug Design, Development and Therapy 9, 2475

3.02

25. HS Rahman, A Rasedee, CW How, NA Zeenathul, MS Chartrand, ...(2015) Antileukemic effect of zerumbone-loaded nanostructured lipid carrier in WEHI-3B cell-induced murine leukemia model, International Journal of Nanomedicine 10, 1649

4.195

26. Govindarajan Karthivashan, Palanisamy Arulselvan, Sharida Fakurazi (2015) Pathways involved in acetaminophen hepatotoxicity with specific targets for inhibition/downregulation, RSC Advances, 5(76), 62040-62051

3.84

27. G Karthivashan, P Arulselvan, AR Alimon, I Safinar Ismail, S Fakurazi (2015) Competing Role of Bioactive Constituents in Moringa oleifera Extract and Conventional Nutrition Feed on the Performance of Cobb 500 Broilers, BioMed Research International, Biomed Res Int.2015:970398. doi: 10.1155/2015/970398

1.579

28. F Barahuie, MZ Hussein, SA Gani, S Fakurazi, Z Zainal (2015) Synthesis of protocatechuic acid–zinc/aluminium–layered double hydroxide nanocomposite as an anticancer nanodelivery system Journal of Solid State Chemistry 221, 21-31

2.133

29. Kura, A. U., Ain, N. M., Hussein, M. Z., Fakurazi, S., & Hussein-Al-Ali, S. H. (2014). Toxicity and metabolism of layered double hydroxide intercalated with levodopa in a parkinson's disease model. International Journal of Molecular Sciences,15(4), 5916-5927.

2.339

30. Kura, A. U., Cheah, P. -., Hussein, M. Z., Hassan, Z., Tengku Azmi, T. I., Hussein, N. F., & Fakurazi, S. (2014). Toxicity evaluation of zinc aluminium levodopa nanocomposite via oral route in repeated dose study. Nanoscale Research Letters, 9(1), 1-11.

2.481

31. Kura, A. U., Fakurazi, S., Hussein, M. Z., & Arulselvan, P. (2014). Nanotechnology in drug delivery: The need for more cell culture based studies in screening. Chemistry Central Journal, 8(1)

1.663

32. Kura, A. U., Hussein, M. Z., Fakurazi, S., & Arulselvan, P. (2014). Layered double hydroxide nanocomposite for drug delivery systems; bio-distribution, toxicity and drug activity enhancement. Chemistry Central Journal, 8(1)

1.663

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33. Kura, A. U., Hussein-Al-Ali, S. H., Hussein, M. Z., & Fakurazi, S. (2014). Preparation of tween 80-Zn/Al-levodopa-layered double hydroxides nanocomposite for drug delivery system. The Scientific World Journal, 2014

1.219

34. Mohsin, S. M. N., Hussein, M. Z., Sarijo, S. H., Fakurazi, S., Arulselvan, P., & Taufiq-Yap, Y. H. (2014). Characterisation and cytotoxicity assessment of UV absorbers-intercalated zinc/aluminium-layered double hydroxides on dermal fibroblast cells. Science of Advanced Materials, 6(4), 648-658.

2.908

35. Mohsin, S. M. N., Hussein, M. Z., Sarijo, S. H., Fakurazi, S., Arulselvan, P., & Taufiq-Yap, Y. H. (2014). Optimization of UV absorptivity of layered double hydroxide by intercalating organic UV-absorbent molecules. Journal of Biomedical Nanotechnology, 10(8), 1490-1500.

7.578

36. Saifullah, B., Arulselvan, P., El Zowalaty, M. E., Fakurazi, S., Webster, T. J., Geilich, B., & Hussein, M. Z. (2014). Development of a highly biocompatible antituberculosis nanodelivery formulation based on para-aminosalicylic acid - zinc layered hydroxide nanocomposites. Scientific World Journal, 2014

1.219

37. Saifullah, B., El Zowalaty, M. E., Arulselvan, P., Fakurazi, S., Webster, T. J., Geilich, B. M., & Hussein, M. Z. (2014). Antimycobacterial, antimicrobial, and biocompatibility properties of para-aminosalicylic acid with zinc layered hydroxide and Zn/Al layered double hydroxide nanocomposites. Drug Design, Development and Therapy, 8, 1029-1036.

3.02

38. Saifullah, B., Palanisamy, A., Ezzat El Zowalaty, M., Fakurazi, S., Webster, T. J., Geilich, B. M., & Hussein, M. Z. (2014). Development of a biocompatible nanodelivery system for tuberculosis drugs based on isoniazid-Mg/Al layered double hydroxide. International Journal of Nanomedicine, 9(1), 4749-4762.

4.195

39. Sellamuthu, P. S., Arulselvan, P., Fakurazi, S., & Kandasamy, M. (2014). Beneficial effects of mangiferin isolated from salacia chinensis on biochemical and hematological parameters in rats with streptozotocininduced diabetes. Pakistan Journal of Pharmaceutical Sciences, 27(1), 161-167.

0.950

40. Tan, J. M., Karthivashan, G., Arulselvan, P., Fakurazi, S., & Hussein, M. Z. (2014). Characterization and in vitro sustained release of silibinin from PH responsive carbon nanotube-based drug delivery system. Journal of Nanomaterials, 2014

1.611

41. Arbabi, L., Baharuldin, M. T. H., Moklas, M. A. M., Fakurazi, S., & Muhammad, S. I. (2014). Antidepressant-like effects of omega-3 fatty acids in postpartum model of depression in rats. Behavioural Brain Research, 271, 65-71.

3.391

42. Arulselvan, P., Ghofar, H. A. A., Karthivashan, G., Halim, M. F. A., Ghafar, M. S. A., & Fakurazi, S. (2014). Antidiabetic therapeutics from natural source: A systematic review. Biomedicine and Preventive Nutrition, 4(4), 607-617

43. Barahuie, F., Hussein, M. Z., Abd Gani, S., Fakurazi, S., & Zainal, Z. (2014). Anticancer nanodelivery system with controlled release property based on protocatechuate-zinc layered hydroxide nanohybrid. International Journal of Nanomedicine, 9(1), 3137-3149.

4.195

44. Barahuie, F., Hussein, M. Z., Arulselvan, P., Fakurazi, S., & Zainal, Z. (2014). Drug delivery system for an anticancer agent, chlorogenate-Zn/Al-layered double hydroxide nanohybrid synthesised using direct co-precipitation and ion exchange methods. Journal of Solid State Chemistry, 217, 31-41.

2.20

45. Barahuie, F., Hussein, M. Z., Fakurazi, S., & Zainal, Z. (2014). Development of 2.339

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drug delivery systems based on layered hydroxides for nanomedicine. International Journal of Molecular Sciences, 15(5), 7750-7786.

46. Barahuie, F., Hussein, M. Z., Gani, S. A., Fakurazi, S., & Zainal, Z. (2015). Synthesis of protocatechuic acid-zinc/aluminium-layered double hydroxide nanocomposite as an anticancer nanodelivery system. Journal of Solid State Chemistry,221, 21-31.

2.20

47. Dorniani, D., Kura, A. U., Hussein, M. Z. B., Fakurazi, S., Shaari, A. H., & Ahmad, Z. (2014). Controlled-release formulation of perindopril erbumine loaded PEG-coated magnetite nanoparticles for biomedical applications. Journal of Materials Science, 49(24), 8487-8497

2.305

48. Dorniani, D., Kura, A. U., Hussein-Al-Ali, S. H., Bin Hussein, M. Z., Fakurazi, S., Shaari, A. H., & Ahmad, Z. (2014). In vitro sustained release study of gallic acid coated with magnetite-PEG and magnetite-PVA for drug delivery system. The Scientific World Journal, 2014

1.219

49. Dorniani, D., Kura, A. U., Hussein-Al-Ali, S. H., Hussein, M. Z. B., Fakurazi, S., Shaari, A. H., & Ahmad, Z. (2014). Release behavior and toxicity profiles towards leukemia (WEHI-3B) cell lines of 6-mercaptopurine-PEG-coated magnetite nanoparticles delivery system. Scientific World Journal, 2014

1.219

50. Hussein-Al-Ali, S. H., Arulselvan, P., Fakurazi, S., & Hussein, M. Z. (2014). The in vitro therapeutic activity of betulinic acid nanocomposite on breast cancer cells (MCF-7) and normal fibroblast cell (3T3). Journal of Materials Science, 49(23), 8171-8182.

2.305

51. Hussein-Al-Ali, S. H., Arulselvan, P., Fakurazi, S., Hussein, M. Z., & Dorniani, D. (2014). Arginine-chitosan- and arginine-polyethylene glycol-conjugated superparamagnetic nanoparticles: Preparation, cytotoxicity and controlled-release.Journal of Biomaterials Applications, 29(2), 186-198

2.764

52. Hussein-Al-Ali, S. H., Arulselvan, P., Hussein, M. Z., Fakurazi, S., Ismail, M., Dorniani, D., & El Zowalaty, M. E. (2014). Erratum: Synthesis, characterization, controlled release and cytotoxic effect of anthranilic acid-loaded chitosan and polyethylene glycol-magnetic nanoparticles on murine macrophage raw 264.7 cells (NANO (2014) 9:2

1.260

53. Hussein-Al-Ali, S. H., El Zowalaty, M. E., Kura, A. U., Geilich, B., Fakurazi, S., Webster, T. J., & Hussein, M. Z. (2014). Antimicrobial and controlled release studies of a novel nystatin conjugated iron oxide nanocomposite. BioMed Research International, 2014

2.706

54. Saifullah, B., Hussein, M. Z., Hussein-Al-Ali, S. H., Arulselvan, P., & Fakurazi, S. (2013). Antituberculosis nanodelivery system with controlled-release properties based on para-amino salicylate-zinc aluminum-layered double-hydroxide nanocomposites. Drug Design, Development and Therapy, 7, 1365-1375.

3.02

55. Saifullah, B., Hussein, M. Z., Hussein-Al-Ali, S. H., Arulselvan, P., & Fakurazi, S. (2013). Sustained release formulation of an anti-tuberculosis drug based on para-amino salicylic acid-zinc layered hydroxide nanocomposite. Chemistry Central Journal, 7(1)

1.663

56. Saleem, A. M., Taufik Hidayat, M., Jais, A. M. M., Fakurazi, S., Moklas, M. A. M., Sulaiman, M. R., . . . Basir, R. (2013). Involvement of monoaminergic system in the antidepressant-like effect of aqueous extract of channa striatus in mice. European Review for Medical and Pharmacological Sciences, 17(15), 2019-2022.

0.988

57. Sellamuthu, P. S., Arulselvan, P., Muniappan, B. P., Fakurazi, S., & Kandasamy, M. (2013). Mangiferin from salacia chinensis prevents oxidative stress and protects pancreatic β-cells in streptozotocin-induced diabetic rats. Journal of Medicinal Food, 16(8), 719-727.

1.699

58. Nur Aimi Syarina Pauzi, Muhammad AA, Sharida Fakurazi, Palanisamy Arulselvan and Zalinah Ahmad. Preliminary study of the optimization of protocol for development of type 2 diabetic model in rats. Indian Journal of Science and Technology, 2013 (in press).

10 /

2

59. Sellamuthu, P. S., Arulselvan, P., Muniappan, B. P., Fakurazi, S., & Kandasamy, M. (2012). Influence of mangiferin on membrane bound phosphatases and lysosomal hydrolases in streptozotocin induced diabetic rats. Latin American Journal of Pharmacy, 31(7), 1013-1020.

0.319

60. Mohsin, S. M. N., Hussein, M. Z., Sarijo, S. H., Fakurazi, S., Arulselvan, P., & Hin, T. -. Y. (2013). Synthesis of (cinnamate-zinc layered hydroxide) intercalation compound for sunscreen application. Chemistry Central Journal, 7(1)

1.663

61. Malahubban, M., Alimon, A. R., Sazili, A. Q., & Fakurazi, S. (2013). Effects of andrographis paniculata and orthosiphon stamineus supplementation in diets on growth performance and carcass characteristics of broiler chickens. International Journal of Agriculture and Biology, 15(5), 897-902.

0.902

62. Al-Qubaisi, M. S., Rasedee, A., Flaifel, M. H., Ahmad, S. H. J., Hussein-Al-Ali, S., Hussein, M. Zobir,El Zowalaty, M. E. (2013). Cytotoxicity of nickel zinc ferrite nanoparticles on cancer cells of epithelial origin. International Journal of Nanomedicine, 8, 2497-2508.

4.195

63. Arulselvan, P., Karthivashan, G., & Fakurazi, S. (2013). Hepatoprotective nature of phytoextracts against hepatotoxin induced animal models: A review. Journal of Chemical and Pharmaceutical Research, 5(7), 233-239

64. Barahuie, F., Hussein, M. Z., Arulselvan, P., Fakurazi, S., & Zainal, Z. (2013). Development of the anticancer potential of a chlorogenate-zinc layered hydroxide nanohybrid with controlled release property against various cancer cells. Science of Advanced Materials, 5(12), 1983-1993

2.908

65. Barahuie, F., Hussein, M. Z., Hussein-Al-Ali, S. H., Arulselvan, P., Fakurazi, S., & Zainal, Z. (2013). Preparation and controlled-release studies of a protocatechuic acid-magnesium/aluminumlayered double hydroxide nanocomposite.International Journal of Nanomedicine, 8, 1975-1987

4.195

66. Dorniani, D., Hussein, M. Z. B., Kura, A. U., Fakurazi, S., Shaari, A. H., & Ahmad, Z. (2013). Preparation and characterization of 6-mercaptopurine-coated magnetite nanoparticles as a drug delivery system. Drug Design, Development and Therapy, 7, 1015-1026

3.02

67. Dorniani, D., Hussein, M. Z. B., Kura, A. U., Fakurazi, S., Shaari, A. H., & Ahmad, Z. (2013). Sustained release of prindopril erbumine from its chitosan-coated magnetic nanoparticles for biomedical applications. International Journal of Molecular Sciences, 14(12), 23639-23653.

2.339

68. Sumaiyah Megat Nabil Mohsin, Mohd Zobir Hussein, Siti Halimah Sarijo, Sharida Fakurazi, Palanisamy Arulselvan and Taufiq Yap. Synthesis of (cinnamate-zinc layered hydroxide) nanohybrid for sunscreen application. Chemistry Central Journal, 7(1), 26, 2013.

3.3

69. Syazana Akmal Sharifudin, Sharida Fakurazi, Mohamad Taufik Hidayat, Ithnin Hairuszah, Mohamad Aris Mohd Moklas, Palanisamy Arulselvan. Therapeutic potential of Moringa oleifera Lam extracts against acetaminophen induced hepatotoxicity in rats. Pharmaceutical Biology, 51(3), 279-88, 2013

1.337

70. Reddi Mohan Naidu Kalla, Ibrahim Khalivulla Shaik, Fakurazi Sharida, Palanisamy Arulselvan, Lasekan Ola, Abas Faridah Synthesis of Bisindolylmethanes and its cytotoxicity properties. International Journal of Molecular Sciences, 14(1), 1843-53, 2013.

2.6

71. Sharida Fakurazi, Abdul Rahman Shamima, Mohamad Taufik Hidayat, Ithnin Hairuszah, Mohamad Aris Mohd Moklas, Palanisamy Arulselvan. Combination of Mitragynine and Morphine Prevents the Development of Morphine Tolerance in Mice. Molecules, 18(1), 666-681, 2013.

2.4

72. Abubakar Amali Muhammad,Nur Aimi Syarina Pauzi, Palanisamy Arulselvan,Faridah Abas, and Sharida Fakurazi (2013) In Vitro Wound Healing Potential and Identification of Bioactive Compounds from Moringa oleifera Lam, BioMed Research International Volume 2013 (2013), Article

2.706

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ID 974580, 10 pages

73. MZ Hussein, J Tan Meihua, S Fakurazi, H Ithnin. The Evolutionary Development in Drug Discovery and Delivery. Journal of Drug Delivery Science and Technology 05/2013; 23(3):195-205.

0.8

74. Siti Aisyah Abd Ghafar, Latifah Saiful Yazan, Sharida Fakurazi, Norsharina Ismail, Kim Wei Chan, ParidahMdTahir and Maznah Ismail, Cytotoxic Activity Of Kenaf Seed Oil Extracted By Supercritical Fluid Extractions (Kso-Sfe) Towards Human Colorectal Cancer (HT29) Cell Lines. Evidence based Complementary and Alternative Medicine, 2013;2013:549705

2.175

75. Farah Barahuie, Samer Hasan Hussein AlAli, Sharida Fakurazi, Palanisamy Arulselvan, Mohd Zobir Hussein. Preparation anticancer drug-Mg/Al- layered double hydroxide nanocomposites by using protocatechuic acid as the active agent and study the controlled release property. International Journal of Nanomedicine, 8:1975-87, 2013

4.195

76. Saifullah Bullo, Mohd Zobir B Hussein, Samer Hasan Hussein-Al-Ali, Palanisamy Arulselvan and Sharida Fakurazi. Sustained release nanocomposite formulation of Multi-drug-resistant tuberculosis (MDR-TB) drug Para amino salicylic acid with Zinc Layered Hydroxide. Chemistry Central Journal, 7(1), 26, 2013.

3.3

77. Masnindah Malahubban, Abd Razak Alimon, Awis Qurni Sazili, Sharida Fakurazi and Zakry FA (2013) Phytochemical analysis of Andrographis paniculata and Orthosiphon stamenius leaf extracts for their antibacterial and antioxidant potential, Tropical Biomedicine, 30(3), 1-14,

0.921

78. Govindarajan Karthivashan, Masoumeh Tangestani Fard, Palanisamy Arulselvan, Faridah Abas, Sharida Fakurazi (2013) Identification of Bioactive Candidate Compounds Responsible for Oxidative Challenge from Hydro-Ethanolic Extract of Moringa oleifera Leaves, Journal of Food Science.

1.775

79. Aminu Umar Kura, Samer Hasan Hussein AlAli, Sharida Fakurazi, Mohd Zobir Hussein, Palanisamy Arulselvan. Development of anti-Parkinson's nanodelivery system with controlled release property using Levodopa as the active agent. International Journal of Nanomedicine, 8, 1103-1110, 2013.

4.195

80. Abdul Rahman Shamima, Sharida Fakurazi, Mohamad Taufik Hidayat, Ithnin Hairuszah, Mohamad Aris Mohd Moklas, Palanisamy Arulselvan. Antinociceptive Action of Isolated Mitragynine from MitragynaSpeciosa through Activation of Opioid Receptor System. International Journal of Molecular Sciences, 13(9), 2012, 11427-11442.

2.6

81. Fakurazi, S., Sharifudin, S.A., Arulselvan, P. Moringa oleifera hydroethanolic extracts effectively alleviate acetaminophen-induced hepatotoxicity in experimental rats through their antioxidant nature. Molecules 17 (7), 2012, 8334-8350

2.4

82. Dena Dorniani, MohdZobir bin Hussein,Aminu Umar Kura, Fakurazi S, Shaari AH, Zalinah Ahmad, Preparation of Fe₃O₄ Magnetic Nanoparticles coated with Gallic acid for Drug Delivery, International Journal of Nanomedicine. 2012, 7, 5745-5756

4.195

83. MohdZobir Hussein, Julia T M Hua, Sharida Fakurazi, HairuszahIthnin, The Evolutionary Development in Drug Discovery and Delivery, J. Drug Del. Sci. Tech.

0.679

84. Saleem, A.M., Hidayat, M.T., Mat Jais, A.M., Fakurazi, S., MohamadMoklas, M.A., Sulaiman, M.R., Amom, Z. (2011)Antidepressant-like effect of aqueous extract of Channastriatus fillet in mice models of depression, European Review for Medical and Pharmacological Sciences 15 (7) , pp. 795-802

1.04

85. Othman, F., Motalleb, G., Peng, S.L.T., Rahmat, A., Fakurazi, S., Pei, C.P. (2011) Extract of Azadirachtaindica (Neem) leaf induces apoptosis in 4T1 breast cancer BALB/c mice. Cell Journal 13 (2) , pp. 107-116

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86. Al-Saffar, F.J., Ganabadi, S., Fakurazi, S.,Yaakub, H.(2011)Zerumbone significantly improved immunoreactivity in the synovium compared to Channastriatus extract in monosodium iodoacetate (MIA)-induced knee osteoarthritis in rat Journal of Medicinal Plant Research5 (9) , pp. 1701-1710

0.879

87. Al-Saffar, F.J.T., Ganabadi, S., Fakurazi, S.,Yaakub, H. (2011) Zerumbone improved immunoreactivity of neuropeptides in monosodium iodoacetate induced knee osteoarthritis in rat. African Journal of Biotechnology 10 (18) , pp. 3646-3653

0.57

88. FayakJabbarTaqi Al-Saffar; ShanthiGanabadi; SharidaFakurazi, Response of ChannaStriatus extract against monosodium iodoacetate induced osteoarthritis in rats, (2011) Journal of Animal and Veterinary Advances,10, 4, 460-469

0.292

89. FayakJabbarTaqi Al-Saffar; ShanthiGanabadi; Sharida Fakurazi; HalimatunYaakub, Response of hepatic metabolizing enzymes and oxidative stress in orally administrated zerumbone against MIA-induced osteoarthritis in rats,(2011) Journal of Animal and Veterinary Advances. 10,5, 566-573

0.292

90. N. Farah Idayu, M. TaufikHidayat, M.A.M. Moklas, F. Sharida, A.R. NurulRaudzah, A.R. Shamima and EvhyApryani Antidepressant-like effect of mitragynine isolated from MitragynaspeciosaKorth in mice model of depression, (2011) Phytomedicine 18, pp. 402-407

2.17

91. Uma N, Fakurazi S,Hairuszah I Moringaoleifera enhances liver antioxidant status via elevation of antioxidant enzymes activity and counteract paracetamol induced hepatotoxicity, (2010) Malaysian J Nutr 16(2), 99-113

92. Apryani, E., TaufikHidayat, M., Moklas, M. A. A., Fakurazi, S.,& Farah Idayu, N. Effects of mitragynine from mitragynaspeciosakorth leaves on working memory.(2010) Journal of Ethnopharmacology, 129(3), 357-360.

3.216

93. Al-Saffar, FJ, Ganabadi S, Yaakub H and Fakurazi S (2009) Collagenase and Sodium Iodoacetate Experimental osteoarthritis model in Sprague Dawley rats, Asian J of Scientific Research, 2(4), 167-179.

94. S Fakurazi et al (2009) Hepatoprotective Action Of Zerumbone AgainstParacetamol Induced Hepatotoxicity, J of Medical Science. 9(3), 161-164.

95. S.Fakurazi, I Hairuszah, ML Jabit and Shanthi G (2008) Reduction of fatty liver formation following zerumbone pretreatment in ethanol induced hepatotoxicity, Journal of Biological Science, 8(8), 1348-1351.

96. S.Fakurazi, I Hairuszah, U Nanthini (2008) MoringaOleifera prevents acetaminophen induced liver injury through restoration of glutathione level, Food and Chemical Toxicology, 46, 2611-2615.

3.078

97. M Moorthy, S Fakurazi, H Ithnin (2008) Morphological Alteration in Mitochondria following Diclofenac and Ibuprofen Administration, Pakistan J of Biological Science, 11(15) 1901-1908

98. Moklas MAA, NurulRauddzah AR, TaufikHidayat M, Sharida F, Farah Idayu N, Zulkhairi A, Shamima M (2008) A preliminary toxicity study of mitragynine, an alkaloid from MitragyninespeciosaKorth, and its effect on locomotor activity in rats, Advances in Medical and Dental Sciences, 2(3), 56-60

99. Zulkhairi A, Zaiton Z, Jamaludin M, Sharida F, TaufikHidayat B, Hasnah B, Nazmi M, Khairul O, Zanariyah A (2008) Alpha Lipoic Acid possess dual antioxidant and lipid lowering properties in atherosclerotic induced New Zealand White rabbit, J Biomedicine and Pharmacotherapy, 62, 716-722.

2.0

100. S.Fakurazi, U. Nanthini, I Hairuszah (2008) Hepatoprotective and Antioxidant action of Moringa oleifera Lam against Acetaminophen induced hepatotoxicity, International J Pharmacology, 4(4), 270-275.

1.5

101. Uma NLG, Fakurazi S,Hairuszah I, Mohanambal M, Taufik MHB, Zulkhairi A, Sukardi S, Ganabadi S, Bahaman AS (2007) Hepatoprotective action of

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MoringaoleiferaLam.PlantaMedica. 73, 971-972 102. Ganabadi S, Sukardi S, Fakurazi S, Yaakub Y (2007) The respond of

immunoreactive nerve fibres in osteoarthritis with orally administered Zingiberofficinale extract. Planta Medica.73, 1010

103. MohdFadzely AB, Arnida T, Asmah R, Fauziah O, Normah H and Sharida F (2006) Antiproliferative properties and antioxidant activity of various types of Strobilanthescrispus tea, International Journal of Cancer Research, 2(2), 152-158

104. Fakurazi S, Hairuszah I, Zulkhairi A, TaufikHidayat B, Mohanambal M (2006) Low Doses of Diclofenac induces Hepatocellular Changes in Rats, Treated in vivo, ActaPharmacologicaSinica, Suppl 1, 357

105. S.Fakurazi, J. Caldwell, C. Corcoran and R.D Goldin (2005) Benoxaprofen Hepatotoxicity; The Aftermath Revealed, Annals of Microscopy, 5, 69-73

106. S.Fakurazi, J. Caldwell, C. Corcoran and R.D Goldin (2005) Benoxaprofen Hepatotoxicity; The Aftermath Revealed, Annals of Microscopy, 5, 69-73

107. S Fakurazi, O Fauziah, EAW Syaren and Z Zenaida (2005) Ibuprofen induces hepatic morphological changes in rat, Annals of Microscopy, 5, 61-68

108. O. Fauziah, Fakurazi S, R Asmah and P Krishnaveni (2005) Transmission electron Microscopy and elemental EDX-SEM analysis of MCF-7 cells treated with Azadirachta indica, Annals of Microscopy, 5, 48-53

109. S Fakurazi, O Fauziah, Y Izatulshima and SA Faezah (2005) Hepar P pretreatment is not hepatoprotective against paracetamol induced injury, Annals of Microscopy, 5, 54-60

110. S.Fakurazi (2004) Benoxaprofen modified liver proteins in mice and rats after single dosing treatment. Malaysian Journal of Pharmaceutical Sciences, 2 (1), 21-37

111. S.Fakurazi, J. Caldwell, C. Corcoran and R.D Goldin (2004) Possible Mitochondria Damage after Benoxaprofen Treatment in Male Sprague-Dawley Rats. Malaysian Journal of Biochemistry and Molecular Biology, 10, 27-31 S.Fakurazi, J. Caldwell, C. Corcoran and RD Goldin (2004) Ibufenac induced greater protein adduct expression than ibuprofen in mouse liver, Malaysian Journal of Biochemistry and Molecular Biology , 10, 32-38

Proceedings Sharida Fakurazi, Aimi Syarina Pauzi, Palanisamy Arulselvan,(2015) Wound Healing Potential of Moringa Oleifera Bioactive Fraction In Diabetic Animal Model; 15TH IUBMB 24TH FAOBMB TSBMB CONFERENCE Sharida Fakurazi, Palanisamy Arulselvan, Aimi Syarina Pauzi Karthivashan Govindarajan, Faridah Abas, Cheah Pike See Topical treatment of blue green algae extract promote healing of diabetic International Conference of Traditional and Complementary Medicine on Health 2013 – National Research Institute of Chinese Medicine – 24-26 May 2013 Palanisamy Arulselvan, Syazana Akmal Sharifuddin, Karthivashan Govindarajan Masoumeh Tangestani Fard, Sharida Fakurazi, Curative potential of Moringa oleifera phytoextracts against acetaminophen induced toxicity in rats. - International Conference of Traditional and Complementary Medicine on Health 2013 – National Research Institute of Chinese Medicine – 24-26 May 2013 International Congress of Molecular Medicine Sharida Fakurazi, Palanisamy Arulselvan, Mohd Zobir HusseinThe safety issues in nanotechnology advancement in drug delivery system, pg 7 International Conference on Structural and Physical Properties of Solids (SPPS 2013) 18-20 Nov 2013 ISBN: 978-93-81212-48-6 Palanisamy Arulselvan Sharida Fakurazi, , Mohd Zobir Hussein Impact of functionalized nanoparticles on inflammation- biological prospective pg 18 International Conference on Structural and Physical Properties of Solids (SPPS 2013) 18-20 Nov 2013 ISBN: 978-93-81212-48-6

Hussein, Mohd. Zobir and Barahuie, Farahnaz and Zainal, Zulkarnain and Arulselvan, Palanisamy and Sharida Fakurazi, (2013) In vitro controlled release of an anticancer drug, chlorogenic acid using magnesium/aluminium layered double hydroxide as nanomatrix. In: 2013

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International Conference on Engineering and Applied Science (ICEAS 2013) , 7 - 9 Nov 2013, Osaka, Japan.

S Fakurazi, , Taufik Hidayat, M, M Aris M, I Hairuszah, Shamima AR, Mitragynine Prevents the development of tolerance following morphine treatment; In Vivo 25; 482, No 3427-30 June 2011 – Yeditepe University, Istanbul, Turkey

S. Fakurazi and H. Ithnin. MoringaOleifera Lam Leaves and Flowers Extract Attenuates Liver Damage against Acetaminophen Intoxication in in vitro acute study (2010). S. Fakurazi, H. Ithnin, M. T. Hidayat and M. A. Mohamad Moklas. Antinociceptive Activity of Mitragynine and its Effects when Combined with Morphine in Mice (2010). S. Fakurazi. Antioxidant Capacity and Hepatoprotective Activity of Moringa Oleifera Lam Leaves and Flowers (2010). Moklas MAM, Adib Ridzuan NR, Taufik Hidayat, M, Nasir FI, Abdul Rahman S, Zulkhairi A, Fakurazi S Toxicity Study of Mitragyna Speciosa extracts using brine shrimp screening test- The 1st international symposium on medicinal plant, their cultivation and aspect of uses, Petra Marriot Hotel, Petra Jordan 15-16. OCT 2008

SFakurazi, I Hairuszah, U Nanthini. HM Taufik, M Aris, A Zulkhairi Efficient Amelioration of acetaminophen induced hepatotoxicity by Moringa oleifera- The 1st international symposium on medicinal plant, their cultivation and aspect of uses, Petra Marriot Hotel, Petra Jordan 15-16. OCT 2008 Zulkhairi A, Kamilah AKK, Azrina A Norhaizan MI, Maznah I, Hasnah B, Sharida F, Aris MM, Taufik HM The effect of Malaysian germinated brown rice in hypercholesterolemia. The 1st international symposium on medicinal plant, their cultivation and aspect of uses, Petra Marriot Hotel, Petra Jordan 15-16. OCT 2008

F Sharida, I Hairuszah, Mohd Lip J, M Mohanambal, NGL Uma, MHB Taufik, A Zulkhairi, G Tahirah, MS Rosmawati (2007) In vivo study: Reduction in fatty liver formation following zerumbone pre treatment. Biology, Chemistry, Pharmacology and Clinical Studies of Asian Plants, Surabaya, Indonesia

Sharida F, Mohanambal M, Uma NGL, Taufik MHB, Zulkhairi A, Hairuszah I (2007) Morphological alterations of mitochondria following diclofenac administration to rats. 19

th

FAOBMB Seoul Conference, Science and Technology for the integration of life. F Sharida, I Hairuszah, M Mohanambal, NGL Uma, MHB Taufik, A Zulkhairi

(2007) Compare

and contrast the effect of diclofenac and ibuprofen on liver mitochondria. 6th

World Congress on the Alternatives and Animal Use in Life Sciences, Tokyo, Japan.. Uma NLG, Fakurazi S, Hairuszah I, Mohanambal M, Taufik MHB, Zulkhairi A, Sukardi S, Ganabadi S, Bahaman AS (2007) Hepatoprotective action of Moringa oleifera Lam. 55

th

International Congress and Annual Meeting of the Society for Medicinal Plant Research. Graz, Austria. Sharida F, Hairuszah I, Mohd Lip J, Mohanambal M, Uma NGL, Taufik MHB, Zulkhairi A, Tahirah G, Rosmawati MS (2007) Hepatoprotection Of Zerumbone Against Ethanol Induced liver Injury; proceedings For Malaysia, Indonesia And Brunei Darussalam Medical Science Conference 2007. The effect of Tinospora crispa aqueous extract intake on repetitive stress rats., Farah Idayu N., Taufik Hidayat M., Siek Ing Ing, Zulkhairi A., Hasnah B., Sharida F., Che Norma M.T., Moklas M.A.M. and Khairul Kamilah A.K. 3

rd Global Summit on Medicinal Plants and Aromatic

Plants (GOSMAP-3), 21-24 Nov 2007, Chiang Mai, Thailand. pg: 198. Therapeutic role of Theobroma cacao and Mitragyna speciosa in depressive disorders model

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on mice. Taufik Hidayat M., Farah Idayu N., Hidatul A.A.R., Sabariah N.A.W., Abd Manan M.J, Amin I., Abbey M., Zulkhairi A., Hasnah B., Sharida F., Jabit M.L. and Khairul Kamilah A.K. 3

rd

Global Summit on Medicinal Plants and Aromatic Plants (GOSMAP-3), 21-24 Nov 2007, Chiang Mai, Thailand. pg: 201. Moklas MAM, Adib Ridzuan NR, Taufik Hidayat, M, Nasir FI, Abdul Rahman S, Zulkhairi A, Fakurazi S Toxicity Study of Mitragyna Speciosa extracts using brine shrimp screening test SFakurazi, I Hairuszah, U Nanthini. HM Taufik, M Aris, A Zulkhairi Efficient Amelioration of acetaminophen induced hepatotoxicity by Moringa oleifera Zulkhairi A, Kamilah AKK, Azrina A Norhaizan MI, Maznah I, Hasnah B, Sharida F, Aris MM, Taufik HM The effect of Malaysian germinated brown rice in hypercholesterolemia The 1

st international symposium on medicinal plant, their cultivation and aspect of uses,

Petra Marriot Hotel, Petra Jordan 15-16. OCT 2008

Publication of

Book Chapter

1. Palanisamy Arulselvan, Arthanari Umamaheswari, Sharida Fakurazi. Medicinal Plants as Antioxidant Agents: Understanding Their Mechanism of Action and Therapeutic Efficacy, Therapeutic approaches for diabetes with natural antioxidants. 2012, ISBN: 978-81-308-0509-2.

2. Sharida Fakurazi, Palanisamy Arulselvan, Mohd Zobir Hussein; The safety issues in nanotechnology advancement in drug delivery system, 2014, ISBN: 978-93-81212-48-6.

3. Palanisamy Arulselvan, Sharida Fakurazi, Mohd Zobir Hussein. Impact of functionalized nanoparticles on Inflammation – Biological prospective, 2014, ISBN: 978-81-308-0509-2.

Intellectual

Property

1. Patent File: 20110001 Application on: 14 January 2011 Title of invention: Methods and compositions for the prevention of opiate tolerance using mitragynine 2.Patent File: Application on:2013 Title of invention: Moringa oleifera crude extracts and their derived fractions with diabetic wound healing properties (status approve- with patent agent) 3. Patent File: Application on:2013 Title of invention: Development of novel sunscreen formulation based on intercalated zinc layered hydroxide and layered double hydroxide nanocomposite 4. Patent File: Application on:2013 Title of invention: Method for the preparation of dual and preferential intercalation of organic UV ray absorbers, benzophenone 4 and eusolex®232, into Zn/Al layered double hydroxide for sunscreen application

2011

H. PROJEK PENYELIDIKAN TERDAHULU(Past Research Project) Project No.

Project Title Role Year Source of fund Status

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1. GP-IPB/2013/9425802

Development of Nanodelivery systems for anti-cancer drugs

Principal investigator

2014 Universiti Putra Malaysia

On-going

2. 02-01-04-SF1144 Determination of the role of CYP450. Inflammation and oxidative stress in the hepatoprotective action of plant natural source

Principal investigator

2012 E-science Complete

3. 04-02-12-2089RU Generation, characterization, and differentiation of skin derived mesenchymal stem and aminiotic fluid stem cells with a novel potential for restoration of wound in diabetes model

Principal investigator

2012 RUGS On-going

4. NND/NA/(1)/TD11-010

Systemic toxicity analysis of nanodelivery drug system

Principal investigator

2012 MOSTI Complete

5. 9323620 Development of interactive computer animated application as a teaching and learning tool in Pharmacology

Principal Investigator

2012 GIPP, UPM Complete

6. 05-02-11-1418RU Evaluation of protein profile in cellular response to metformin monotherapy in diabetic type 2 patients

Principal investigator

2011 RUGS Complete

7. 05-02-11-1419 RU Effect of tropical bioactive compound on incision wound healing in diabetic rats

Principal investigator

2011 RUGS Complete

8. 05-01-04-SF1148 Enhancing antioxidant activities of poultry meat and eggs through dietary supplement with Moringaoleifera leaf and flowers

Principal investigator

2011 SCIENCEFUND R&D Pertanian

Complete

9. 04-10-882FR Protein Profiling of diabetic patients with different responses towards first line oral anti-diabetic metformin drug

Principal investigator

2011 MOHE Completed

10. 04-01-07-0116 RU A study on opioid adn cannabinoid receptor in regulating antinociceptive activities following morphine and Mitragynine

Principal investigator

2007 RUGS Completed

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combination, administered to rats in vivo

11. 04-11-08-630FR Hepatoprotective effect of Moringaoleifera Lam. Investigation on the mechanism of action

Principal investigator

2009 MOHE Completed

12. 04-01-07-102 FR Investigation on the expression of opioid and cannabinoid receptor proteins following combination treatment of mitragynine and morphine

Principal investigator

2006 FRGS Completed

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I. SUPERVISION OF POST-GRADUATE STUDENTS Graduated Students

1. PhD Shamima Abdul Rahman

Enhanced antinociceptive effects of mitragynine in combination with morphine via opiod receptor activation

Supervisor

2. PhD Aminu Umar Kura* Characterisation and toxicity assessment of zinc/aluminium layered double hydroxide levodopa nanocomposite

Supervisor

*Completed his work within 6 Semesters 3. PhD Siti Aisyah Abd Ghafar Effects of Supercritical Fluid Extraction of

Hibicus cannabinus L seed oil extract on colon cancer in vitro and in vivo

Co-SV

4. PhD Masnindah Malahubban

Potential use of Andrographis paniculata and Orthosiphon stamineus as alternative to antibiotic growth promoter for broiler chicken

Co-SV

5. PhD Farahnez Barahuie Design and Synthesis of drug nano delivery system using layered double hydroxide (LDH) and zinc layered hydroxide (ZLH).

Co-SV

6. PhD Saifullah Bullo Development of a Highly Biocompatible Antituberculosis Nanodelivery Formulation Based on Para-Aminosalicylic Acid, and isoniazid-Zinc Layered Hydroxide (LDH) or graphene Nanocomposites

Co-SV

7. PhD Fayak Jabbar Efficacy Of Channa Striatus Aqueous Extract And Zerumbone In Alleviating Induced Knee Osteoarthritis In Rats

Co-SV

1. MSc Mohanambal a/p Moorthy Mitochondrial Ultrastructural Study Following diclofenac and Ibuprofen Treatment

Supervisor

2. MSc Uma Nanthini a/p Gaudar Linggi

A study on Moringa oleifera and its antioxidant status

Supervisor

3. MSc Syazana Akmal Syarifuddin Antioxidant properties of leaf and flower extracts of Moringa oleifera Lam and their effects on acetaminophen induced hepatotoxicity in vivo.

Supervisor

4. MSc Masoumeh Tangestani The Anti inflammatory effect of Moringa oleifera leaves bioactive extract on inflammatory production by LPS-Stimulated RAW 264.7 Murine Macrophage Cell Lines.

Supervisor

5. MSc Malik Adewoyin Anti-inflammatory potential of zinc layered hydroxide intercalated with cinnamic acid (zca-nanohybrid) in LPS-induced inflammation using raw 264.7 macrophage

Supervisor

6. MSc Nur Aimi Syarina Pauzi Effects of blue-green microalgae aqueous extract on incision wound healing in diabetic rats.

Supervisor

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1. MSc Mohd Fadzelly Abu Bakar Possible Antidiabetic Effect of Strobilanthes Crispus

Co-SV

2. MSc Lam Su Peng Co-SV 3. MSc Norhayati Mohd Monzai Co-SV 4. MSc Evhy Apriyani Effects of mitragynine from Mitragyna

speciosa Korth on working memory in mice Co-SV

5. MSc Leila Arbi Antidepressant like effects of Manhaden Fish oil in post partum induced model of depression in rats

Co-SV

6. MSc Noridzzaida Ridzuan Isolation and Characterisation of rat bone marrow mesenchymal stem cells

Co-SV

7. MSc Nurul Raudzah Binti Adib Ridzuan

Effect of Mitragynine on Locomotor and Anxiety in rats subjected to restrained stress

Co-Sv

8. MSc Farah Idayu binti Nasir Possible antidepressant properties of Mitragynine, an alkaloid from Mitragyna speciosa Korth, in experimental models of depression

Supervision of Students

J.EXTERNAL EXAMINERS PROGRAMS University Program/Course Level Date of Appointment

International Medical School, Management And Science University, Shah Alam Campus

PROFESSIONAL II (MBBS)

UG 23rd

-27th July 2012

K.EXTERNAL EXAMINERS THESIS University Thesis title Name of candidate MSc/PhD

University of Cairo, Egypt

A physiological study to assess antioxidative activity of rutin against isoniazid in albino rats

Fatma Abdel AzimYousefSanad

PhD

UniversitiKebangsaan Malaysia

SitiSuriani Omar MSc

L.IXTERNAL EXAMINERS THESIS Year Name of candidate Thesis title MSc/PhD

2013 Nurul Huda MohdZairi (GS22437)

Roles of zinc abating lead toxicity MSc

2013 HermaleezaRoslee (GS22104)

Comparing the effect of paracetamol on human Chang liver cells infected by dengue viruses based on liver enzymes activity

MSc

2012 PushpaGandi a/p Sangaran (GS20500)

Identification of potential protein markers for gestational diabetes

MSc

2012 Cini Mathew John (GS27361)

Evaluation of antidiabetic and immunomodulatory activity of polyphenols derived from Cassia Auriculata in hyperglycaemic model

MSc

2011 SimaAlishavandi (GS Effect of gamma-oryzanol, oryzanol rich fraction and fractionated components on colorectal cancer cell line (HT-29) and cytokine production of human pheripheral blood mononuclear cell (PBMC)

MSc

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2011 Foo JhiBiau (GS23019) In vitro cytotoxicity and in vivo antitumour properties of kenaf seed oil towards leukemia

MSc

2011 Omar Al Harasstani (GS22016)

Flavonoid Synergism in models of inflammation

MSc

2011 ElhamRastegari (GS21297)

Identification of abundantly expressed protein from curculigolatifolia fruit, root and leaf through optimised extraction protocols

MSc

2010 Liew Choi Yi (GS20198) Determining the molecular taret of the anti-inflammatory compound HMP (3-(2-hydroxyphenyl)-1-(5-methyl-furan-2-y-l)propenone

MSc

2009 RadhaKodiappan (GS14933)

Single nucleotide polymorphisms of the human fatty acid amide hydrolase gene and its association to the risk of drug addiction in Malaysian subjects

MSc

2012 Lee KaHeng (GS20485) Immunomodulatory action of new curcumin analogue (2,6-Bis(2,5-dimethoxybenzylidene)cyclohexanone] on major inflammatory mediator expression in activated macrophage and synovial fibroblast cells

PhD

2011 Enoch Kumar a/l Perimal (GS19860)

Antinociceptive and anti-inflammatory activities of zerumbone and its possible mechanism of action

PhD

2011 Ho Ket Li (GS18835) Anticolorectal cancer properties of vanillin in vitro and in vivo

PhD

M.CHAIRMAN OF EXAMINATION COMMITTEE Year Name of candidate Thesis title MSc/PhD 2013 Tay Tan Chow (GS23158) Analysis of HSP27, APC and Catenin

protein expressions in gastric cancer, chronic atrophic gastritis and helicobactor pylori-associated chronic gastritis

MSc

2012 SeyedDavoudJazayeri (GS21934)

Development of oral avian influenza virus subtype H5 DNA vaccines using attenuated Salmonella typhimurium and silver nanoparticles carrier

PhD

2012 Daryl B. Jesus Arapoc (GS24020)

The antioxidant activity of hibiscus cannabinus leaf aqueous extract on human umbilical vein endothelial cells (HUVECs) and its potential benefit in experimental artherosclerosis in vitro

MSc

2012 ChoongOiKuan (GS25670) Interaction of triple helix forming oligonucleotide (TFO) with feline infectious peritonitis virus (FIPV) genome and its effect on FIPV replication

MSc

2012 Muhammad Syamsul Reza Harun (GS23434)

Transcriptome and apoptosis studies on feline infectious peritonitis virus infected crandellrees feline kidney cells

MSc

2012 AimiMelatiMahlid@Hanafi (GS24898)

Oral delivery of cellulose acetate phthalate-microencapsulated cholera DNA vaccine

MSc

2011 Wan MasturaShaik Mohammed Mossadeq (GS14332)

Antinociceptive and anti-inflammatory effects of mitragynaspeciosakorthmethanolic extract in rodents

PhD

2011 Lam Kian Lam (GS18470) Towards the development of avian PhD

21 /

2

influenza virus DNA vaccine with chicken IL-15 and IL-18 as adjuvant

2011 NurulHafizahSamsudin Analyses of HER2, NM23, and K-RAS in gastric cancer and helicobacter pylori associated chronic gastritis

MSc

2010 Mohd Kamal Hassan Antioxidative and anti-inflammatory effect of Anacardiumoccidentale Linn Leaves extract on H2O2 and TNF induced human umbilical vein endothelial cells (HUVECs) in early stage of atherosclerosis

MSc

Number of students graduated

Program Status As a

chairman

As a

member

PhD Graduated 3 7

On going 3 6

Masters Graduated 6 8

On going 5 5