22

DAFTAR PUSTAKA

1. Mengenal beberapa tanaman yang digunakan sebagai antidiabetika [home

page on the internet]. c2005 [cited 17 Februari 2012]. Available from :

http://www.pom.go.id/public/berita_aktual/detail.asp?id=74&qs_menuid=2

2. Health research agenda for the 21st Century: Country Perspectives-Indonesia

[ home page on the internet ]. c2005 [cited 17 Februari 2012 ]. Available

from : http://www.whosea.org/researchpolicy/54ACHR.htm.diakses 2 Juli

2005

3. Galicia E.H., Contreras A.A., Santamaria L.A., Miranda A.A.C., Vega

L.M.G., Saenz J.L.F, et al. studies on Hypoglycemic Activity of Mexican

Medical Plants. In: Proc. West. Pharmacol. Soc 45, 2002; p. 118-24

4. Muhlisah F. Tanaman Obat Keluarga. Jakarta: PT. Penebar Swadaya; 2001

5. Santosa M.H dan Zaini N.C. Prospek Tantangan Penelitian, dan

Pengembangan Tanaman Obat Untuk Terapi Diabetes. Surakarta; 2002

6. Wikipedia.org., 2009, GulaDarah, http://id.wikipedia.org/wiki/guladarah, dikutip 16

Februari 2012.

7. Irawan, M.A., 2007, GlukosadanMetabolismeKarbohidrat, Polton Sports Science &

Performance Lab, Sports Science Brief, No. 6, Volume 01 (2007), No. 1-5

8. Schteingart, D.E., 2006, dalam Price, S.A., dan Wilson, L.M., Patofisiologi:

KonsepKlinis Proses-proses Penyakit, Edisi 6, Jakarta, EGC, 1259-1267

23

9. Soegondo, S., 2007, HiperglikemiaGulaDarahTinggi, RentanKomplikasi, Rabu, 28

November 2007, http://www.susukolostrum.com/berita-terbaru-othermenu-51/info-

sehat-othermenu-65, dikutiptanggal 22 Januari 2012.

10. DirekturGiziMasyarakatDirektoratJenderalBinaKesehatanMasyarakatDepartemenKe

sehatan RI, 2003, PeranDiitdalamPenanggulangan Diabetes,

DisampaikandalamSeminar Pekan Diabetes Tanggal 25 – 27 Maret 2003 di Depkes

RI.

11. Sinha R, Fisco G, Teague B, Tamborlane WV, Banyas B, et al. Prevalence of

Impaired Glucose Tolerance Among Children and Adolescents with Mark

Obesity. N Engl J Med. 2002; p. 802-10

12. Tjokorda Gede Dalem Pemayun. Kontroversi dalam Penanganan Diabetes

Melitus Ditinjau dari Berbagai Aspek Penyakit Dalam. Semarang: Badan

Penerbit UNDIP (PERKENI) : 2007; p. 37 – 49

13. Mayes PA. Glikoneogenesis dan Pengontrolan Kadar Glukosa Darah. In:

Murray RK, Granner DK, Mayes PA, Rodwell VW. Biokimia Harper.

Jakarta: EGC, 2003; p. 201

14. WHO. Prevention of Diabetes Mellitus Technical Report Series 844. Geneva

: 1994

24

LAMPIRAN I.

25

LAMPIRAN II. Tabel kadar glukosa darah yang diberi ekstrak kayu manis.

kelompok tikus ke kadar glukosa darah mg/dl

normal post treat 30 menit ke-

pre 1 2 3 4

k- 1 95 172 163 166 152 143

2 86 167 169 157 148 139

3 78 165 163 159 147 141

4 69 163 169 165 157 142

5 87 175 173 150 154 141

Rerata

83 168,4 167,4 159,4 151,6 141,2

K1 1 98 162 158 143 131 126

2 100 164 159 148 142 128

3 80 158 157 151 134 129

4 82 173 169 148 150 135

5 87 166 155 159 142 127

Rerata 89,4 164,6 159,6 149,8 139,8 129

K2 1 83 162 143 136 130 117

2 75 170 152 135 129 114

3 84 163 156 141 126 119

4 85 167 158 138 128 116

5 92 174 162 132 133 120

Rerata 83,8 167,2 154,2 136,4 129,2 117,2

K3 1 110 159 148 124 110 83

2 93 167 140 111 124 89

3 87 163 149 119 112 97

4 84 154 147 121 114 91

5 100 171 154 121 108 93

Rerata 94,8 162,8 147,6 119,2 113,6 90,6

gliben 1 77 172 128 122 100 75

2 88 159 138 105 94 81

3 73 163 132 104 99 82

4 82 166 127 97 106 84

5 77 155 133 108 107 89

79,4 163 131,6 107,2 101,2 82,2

26

Lampiran III. KONVERSI PERHITUNGAN DOSIS (LAURENCE &

BACHARACH, 1964)

Mencit

20 gr

Tikus

200

gr

Marmot

400 gr

Kelinci

1,5 kg

Kucing

2 kg

Kera

4 kg

Anjing

12 kg

Manusia

70 kg

Mencit

20 gr

1.0 7.0 12.25 27.8 29.7 64.1 124.2 387.9

Tikus

200 gr

0.14 1.0 1.74 3.9 4.2 9.2 17.8 56.0

Marmot

400 gr

0.08 0.57 1.0 2.25 2.4 5.2 10.2 31.5

Kelinci

1,5 kg

0.04 0.25 0.44 1.0 1.08 2.4 4.5 14.2

Kucing

2 kg

0.03 0.23 0.41 0.92 1.0 2.2 4.1 13.0

Kera 4

kg

0.016 0.11 0.19 0.42 0.45 1.0 1.9 6.1

Anjing

12 kg

0.008 0.06 0.1 0.22 0.24 0.52 1.0 3.1

Manusia

70 kg

0.0026 0.018 0.031 0.07 0.076 0.16 0.32 1.0

27

Lampiran IV

DOSIS KONVERSI

1. Ekstrak kayu manis (Cinnamomun burmannii)

Dihitung dengan menggunakan rumus berdasarkan konversi

perhitungan dosis antara jenis hewan (LAURENCE & BACHARACH,

1964)

1. Konversi dosis manusia (70 kg) ke tikus (200 gram ) = 0,018

2. Dosis kayu manis pada manusia (70 kg) = 420 gram

3. Dosis kayu manis-tikus (200 gram) = 70/70 x 0,018 x 420

= 7,56 gram / 200grBB

4. Kemudian diturunkan dan dinaikan sesuai deret ukur menjadi :

1. 7,56 gr / 2 = 3,78 gram / 200grBB

2. 7,56 gr x 2 = 15,12 gram / 200grBB

2. Dosis Glukosa yang dipakai

Dihitung dengan menggunakan rumus berdasarkan konversi

perhitungan dosis antara jenis hewan (LAURENCE & BACHARACH,

1964)

1. Konversi dosis manusia (70 kg) ke tikus (200 gram) = 0,018

28

2. Dosis glukosa pada manusia = 75 gram

3. Dosis glukosa manusia-tikus (200 gram) = 0,018 x 75

= 1,35 gram /

200grBB

3. Dosis Glibenklamid

Dihitung dengan menggunakan rumus berdasarkan konversi

perhitungan dosis antara jenis hewan (LAURENCE &

BACHARACH, 1964)

1. Konversi dosis manusia (70 kg) ke tikus (200 gram) = 0,018

2. Dosis glibenklamid pada manusia (70 kg) = 5 gram

3. Dosis glibenklamid manusia-tikus (200 gram) = 70/70 x 0,018

x 5

=0,09gram/200grBB

Explore

Kelompok

29

Case Summaries

5 5 5 5 5 5

83.00 168.40 167.40 159.40 151.60 141.20

9.874 4.980 4.336 6.504 4.159 1.483

86.00 167.00 169.00 159.00 152.00 141.00

69 163 163 150 147 139

95 175 173 166 157 143

5 5 5 5 5 5

89.40 164.60 159.60 149.80 139.80 129.00

9.154 5.550 5.459 5.891 7.497 3.536

87.00 164.00 158.00 148.00 142.00 128.00

80 158 155 143 131 126

100 173 169 159 150 135

5 5 5 5 5 5

83.80 167.20 154.20 136.40 129.20 117.20

6.058 4.970 7.225 3.362 2.588 2.387

84.00 167.00 156.00 136.00 129.00 117.00

75 162 143 132 126 114

92 174 162 141 133 120

5 5 5 5 5 5

94.80 162.80 147.60 119.20 113.60 90.60

10.474 6.648 5.030 4.919 6.229 5.177

93.00 163.00 148.00 121.00 112.00 91.00

84 154 140 111 108 83

110 171 154 124 124 97

5 5 5 5 5 5

79.40 163.00 131.60 107.20 101.20 82.20

5.771 6.519 4.393 9.203 5.357 5.070

77.00 163.00 132.00 105.00 100.00 82.00

73 155 127 97 94 75

88 172 138 122 107 89

25 25 25 25 25 25

86.08 165.20 152.08 134.40 127.08 112.04

9.522 5.752 13.320 20.386 19.024 23.153

85.00 165.00 155.00 136.00 129.00 117.00

69 154 127 97 94 75

110 175 173 166 157 143

N

Mean

Std. Dev iation

Median

Minimum

Maximum

N

Mean

Std. Dev iation

Median

Minimum

Maximum

N

Mean

Std. Dev iation

Median

Minimum

Maximum

N

Mean

Std. Dev iation

Median

Minimum

Maximum

N

Mean

Std. Dev iation

Median

Minimum

Maximum

N

Mean

Std. Dev iation

Median

Minimum

Maximum

Kelompok

K-

K1

K2

K3

Gliben

Total

Normal GD pre GD post 1 GD post 2 GD post 3 GD post 4

30

Tests of Normality

.219 5 .200* .970 5 .877

.226 5 .200* .878 5 .300

.247 5 .200* .946 5 .705

.172 5 .200* .950 5 .738

.261 5 .200* .938 5 .650

.211 5 .200* .942 5 .678

.200 5 .200* .971 5 .879

.201 5 .200* .946 5 .705

.136 5 .200* .990 5 .980

.130 5 .200* .992 5 .987

.245 5 .200* .871 5 .272

.344 5 .054 .804 5 .087

.198 5 .200* .949 5 .730

.253 5 .200* .947 5 .713

.194 5 .200* .940 5 .665

.205 5 .200* .933 5 .618

.220 5 .200* .929 5 .593

.147 5 .200* .995 5 .994

.284 5 .200* .860 5 .228

.265 5 .200* .912 5 .482

.207 5 .200* .947 5 .715

.215 5 .200* .943 5 .687

.179 5 .200* .984 5 .955

.274 5 .200* .867 5 .254

.215 5 .200* .929 5 .593

.246 5 .200* .956 5 .777

.300 5 .161 .836 5 .154

.175 5 .200* .974 5 .899

.179 5 .200* .984 5 .955

.206 5 .200* .978 5 .926

Kelompok

K-

K1

K2

K3

Gliben

K-

K1

K2

K3

Gliben

K-

K1

K2

K3

Gliben

K-

K1

K2

K3

Gliben

K-

K1

K2

K3

Gliben

K-

K1

K2

K3

Gliben

Normal

GD pre

GD post 1

GD post 2

GD post 3

GD post 4

Stat ist ic df Sig. Stat ist ic df Sig.

Kolmogorov -Smirnova

Shapiro-Wilk

This is a lower bound of the true signif icance.*.

Lillief ors Signif icance Correctiona.

31

Test of Homogeneity of Variance

1.161 4 20 .358

.602 4 20 .665

.602 4 17.671 .666

1.124 4 20 .373

.156 4 20 .958

.165 4 20 .954

.165 4 18.857 .954

.160 4 20 .956

.385 4 20 .817

.220 4 20 .924

.220 4 16.456 .924

.360 4 20 .834

.688 4 20 .609

.447 4 20 .773

.447 4 13.230 .773

.670 4 20 .620

1.305 4 20 .302

.659 4 20 .628

.659 4 13.392 .631

1.304 4 20 .302

1.068 4 20 .398

.923 4 20 .470

.923 4 13.739 .479

1.049 4 20 .407

Based on Mean

Based on Median

Based on Median and

with adjusted df

Based on trimmed mean

Based on Mean

Based on Median

Based on Median and

with adjusted df

Based on trimmed mean

Based on Mean

Based on Median

Based on Median and

with adjusted df

Based on trimmed mean

Based on Mean

Based on Median

Based on Median and

with adjusted df

Based on trimmed mean

Based on Mean

Based on Median

Based on Median and

with adjusted df

Based on trimmed mean

Based on Mean

Based on Median

Based on Median and

with adjusted df

Based on trimmed mean

Normal

GD pre

GD post 1

GD post 2

GD post 3

GD post 4

Levene

Stat istic df1 df2 Sig.

Normal

32

GD pre

GD post 1

33

GD post 2

GD post 3

34

GD post 4

Oneway

35

ANOVA

Normal

731.840 4 182.960 2.534 .072

1444.000 20 72.200

2175.840 24

Between Groups

Within Groups

Total

Sum of

Squares df Mean Square F Sig.

Post Hoc Tests

36

Multiple Comparisons

Dependent Variable: Normal

Tukey HSD

-6.400 5.374 .756 -22.48 9.68

-.800 5.374 1.000 -16.88 15.28

-11.800 5.374 .222 -27.88 4.28

3.600 5.374 .961 -12.48 19.68

6.400 5.374 .756 -9.68 22.48

5.600 5.374 .833 -10.48 21.68

-5.400 5.374 .850 -21.48 10.68

10.000 5.374 .369 -6.08 26.08

.800 5.374 1.000 -15.28 16.88

-5.600 5.374 .833 -21.68 10.48

-11.000 5.374 .281 -27.08 5.08

4.400 5.374 .922 -11.68 20.48

11.800 5.374 .222 -4.28 27.88

5.400 5.374 .850 -10.68 21.48

11.000 5.374 .281 -5.08 27.08

15.400 5.374 .065 -.68 31.48

-3.600 5.374 .961 -19.68 12.48

-10.000 5.374 .369 -26.08 6.08

-4.400 5.374 .922 -20.48 11.68

-15.400 5.374 .065 -31.48 .68

(J) Kelompok

K1

K2

K3

Gliben

K-

K2

K3

Gliben

K-

K1

K3

Gliben

K-

K1

K2

Gliben

K-

K1

K2

K3

(I) Kelompok

K-

K1

K2

K3

Gliben

Mean

Dif f erence

(I-J) Std. Error Sig. Lower Bound Upper Bound

95% Conf idence Interv al

Homogeneous Subsets

37

Normal

Tukey HSDa

5 79.40

5 83.00

5 83.80

5 89.40

5 94.80

.065

Kelompok

Gliben

K-

K2

K1

K3

Sig.

N 1

Subset

f or alpha

= .05

Means for groups in homogeneous subsets are display ed.

Uses Harmonic Mean Sample Size = 5.000.a.

Oneway

ANOVA

GD pre

126.000 4 31.500 .943 .460

668.000 20 33.400

794.000 24

Between Groups

Within Groups

Total

Sum of

Squares df Mean Square F Sig.

Post Hoc Tests

38

Multiple Comparisons

Dependent Variable: GD pre

Tukey HSD

3.800 3.655 .834 -7.14 14.74

1.200 3.655 .997 -9.74 12.14

5.600 3.655 .555 -5.34 16.54

5.400 3.655 .588 -5.54 16.34

-3.800 3.655 .834 -14.74 7.14

-2.600 3.655 .951 -13.54 8.34

1.800 3.655 .987 -9.14 12.74

1.600 3.655 .992 -9.34 12.54

-1.200 3.655 .997 -12.14 9.74

2.600 3.655 .951 -8.34 13.54

4.400 3.655 .749 -6.54 15.34

4.200 3.655 .779 -6.74 15.14

-5.600 3.655 .555 -16.54 5.34

-1.800 3.655 .987 -12.74 9.14

-4.400 3.655 .749 -15.34 6.54

-.200 3.655 1.000 -11.14 10.74

-5.400 3.655 .588 -16.34 5.54

-1.600 3.655 .992 -12.54 9.34

-4.200 3.655 .779 -15.14 6.74

.200 3.655 1.000 -10.74 11.14

(J) Kelompok

K1

K2

K3

Gliben

K-

K2

K3

Gliben

K-

K1

K3

Gliben

K-

K1

K2

Gliben

K-

K1

K2

K3

(I) Kelompok

K-

K1

K2

K3

Gliben

Mean

Dif f erence

(I-J) Std. Error Sig. Lower Bound Upper Bound

95% Conf idence Interv al

Homogeneous Subsets

39

GD pre

Tukey HSDa

5 162.80

5 163.00

5 164.60

5 167.20

5 168.40

.555

Kelompok

K3

Gliben

K1

K2

K-

Sig.

N 1

Subset

f or alpha

= .05

Means for groups in homogeneous subsets are display ed.

Uses Harmonic Mean Sample Size = 5.000.a.

Oneway

ANOVA

GD post 1

3676.240 4 919.060 31.605 .000

581.600 20 29.080

4257.840 24

Between Groups

Within Groups

Total

Sum of

Squares df Mean Square F Sig.

Post Hoc Tests

40

Multiple Comparisons

Dependent Variable: GD post 1

Tukey HSD

7.800 3.411 .190 -2.41 18.01

13.200* 3.411 .008 2.99 23.41

19.800* 3.411 .000 9.59 30.01

35.800* 3.411 .000 25.59 46.01

-7.800 3.411 .190 -18.01 2.41

5.400 3.411 .524 -4.81 15.61

12.000* 3.411 .016 1.79 22.21

28.000* 3.411 .000 17.79 38.21

-13.200* 3.411 .008 -23.41 -2.99

-5.400 3.411 .524 -15.61 4.81

6.600 3.411 .332 -3.61 16.81

22.600* 3.411 .000 12.39 32.81

-19.800* 3.411 .000 -30.01 -9.59

-12.000* 3.411 .016 -22.21 -1.79

-6.600 3.411 .332 -16.81 3.61

16.000* 3.411 .001 5.79 26.21

-35.800* 3.411 .000 -46.01 -25.59

-28.000* 3.411 .000 -38.21 -17.79

-22.600* 3.411 .000 -32.81 -12.39

-16.000* 3.411 .001 -26.21 -5.79

(J) Kelompok

K1

K2

K3

Gliben

K-

K2

K3

Gliben

K-

K1

K3

Gliben

K-

K1

K2

Gliben

K-

K1

K2

K3

(I) Kelompok

K-

K1

K2

K3

Gliben

Mean

Dif f erence

(I-J) Std. Error Sig. Lower Bound Upper Bound

95% Conf idence Interv al

The mean dif f erence is signif icant at the .05 lev el.*.

Homogeneous Subsets

41

GD post 1

Tukey HSDa

5 131.60

5 147.60

5 154.20 154.20

5 159.60 159.60

5 167.40

1.000 .332 .524 .190

Kelompok

Gliben

K3

K2

K1

K-

Sig.

N 1 2 3 4

Subset f or alpha = .05

Means for groups in homogeneous subsets are displayed.

Uses Harmonic Mean Sample Size = 5.000.a.

42

Oneway

ANOVA

GD post 2

9185.200 4 2296.300 58.223 .000

788.800 20 39.440

9974.000 24

Between Groups

Within Groups

Total

Sum of

Squares df Mean Square F Sig.

Post Hoc Tests

43

Multiple Comparisons

Dependent Variable: GD post 2

Tukey HSD

9.600 3.972 .152 -2.29 21.49

23.000* 3.972 .000 11.11 34.89

40.200* 3.972 .000 28.31 52.09

52.200* 3.972 .000 40.31 64.09

-9.600 3.972 .152 -21.49 2.29

13.400* 3.972 .022 1.51 25.29

30.600* 3.972 .000 18.71 42.49

42.600* 3.972 .000 30.71 54.49

-23.000* 3.972 .000 -34.89 -11.11

-13.400* 3.972 .022 -25.29 -1.51

17.200* 3.972 .003 5.31 29.09

29.200* 3.972 .000 17.31 41.09

-40.200* 3.972 .000 -52.09 -28.31

-30.600* 3.972 .000 -42.49 -18.71

-17.200* 3.972 .003 -29.09 -5.31

12.000* 3.972 .047 .11 23.89

-52.200* 3.972 .000 -64.09 -40.31

-42.600* 3.972 .000 -54.49 -30.71

-29.200* 3.972 .000 -41.09 -17.31

-12.000* 3.972 .047 -23.89 -.11

(J) Kelompok

K1

K2

K3

Gliben

K-

K2

K3

Gliben

K-

K1

K3

Gliben

K-

K1

K2

Gliben

K-

K1

K2

K3

(I) Kelompok

K-

K1

K2

K3

Gliben

Mean

Dif f erence

(I-J) Std. Error Sig. Lower Bound Upper Bound

95% Conf idence Interv al

The mean dif f erence is signif icant at the .05 lev el.*.

Homogeneous Subsets

44

GD post 2

Tukey HSDa

5 107.20

5 119.20

5 136.40

5 149.80

5 159.40

1.000 1.000 1.000 .152

Kelompok

Gliben

K3

K2

K1

K-

Sig.

N 1 2 3 4

Subset f or alpha = .05

Means for groups in homogeneous subsets are displayed.

Uses Harmonic Mean Sample Size = 5.000.a.

Oneway

ANOVA

GD post 3

8095.040 4 2023.760 68.509 .000

590.800 20 29.540

8685.840 24

Between Groups

Within Groups

Total

Sum of

Squares df Mean Square F Sig.

Post Hoc Tests

45

Multiple Comparisons

Dependent Variable: GD post 3

Tukey HSD

11.800* 3.437 .020 1.51 22.09

22.400* 3.437 .000 12.11 32.69

38.000* 3.437 .000 27.71 48.29

50.400* 3.437 .000 40.11 60.69

-11.800* 3.437 .020 -22.09 -1.51

10.600* 3.437 .041 .31 20.89

26.200* 3.437 .000 15.91 36.49

38.600* 3.437 .000 28.31 48.89

-22.400* 3.437 .000 -32.69 -12.11

-10.600* 3.437 .041 -20.89 -.31

15.600* 3.437 .002 5.31 25.89

28.000* 3.437 .000 17.71 38.29

-38.000* 3.437 .000 -48.29 -27.71

-26.200* 3.437 .000 -36.49 -15.91

-15.600* 3.437 .002 -25.89 -5.31

12.400* 3.437 .013 2.11 22.69

-50.400* 3.437 .000 -60.69 -40.11

-38.600* 3.437 .000 -48.89 -28.31

-28.000* 3.437 .000 -38.29 -17.71

-12.400* 3.437 .013 -22.69 -2.11

(J) Kelompok

K1

K2

K3

Gliben

K-

K2

K3

Gliben

K-

K1

K3

Gliben

K-

K1

K2

Gliben

K-

K1

K2

K3

(I) Kelompok

K-

K1

K2

K3

Gliben

Mean

Dif f erence

(I-J) Std. Error Sig. Lower Bound Upper Bound

95% Conf idence Interv al

The mean dif f erence is signif icant at the .05 lev el.*.

Homogeneous Subsets

46

GD post 3

Tukey HSDa

5 101.20

5 113.60

5 129.20

5 139.80

5 151.60

1.000 1.000 1.000 1.000 1.000

Kelompok

Gliben

K3

K2

K1

K-

Sig.

N 1 2 3 4 5

Subset f or alpha = .05

Means for groups in homogeneous subsets are displayed.

Uses Harmonic Mean Sample Size = 5.000.a.

Oneway

ANOVA

GD post 4

12573.360 4 3143.340 215.593 .000

291.600 20 14.580

12864.960 24

Between Groups

Within Groups

Total

Sum of

Squares df Mean Square F Sig.

Post Hoc Tests

47

Multiple Comparisons

Dependent Variable: GD post 4

Tukey HSD

12.200* 2.415 .001 4.97 19.43

24.000* 2.415 .000 16.77 31.23

50.600* 2.415 .000 43.37 57.83

59.000* 2.415 .000 51.77 66.23

-12.200* 2.415 .001 -19.43 -4.97

11.800* 2.415 .001 4.57 19.03

38.400* 2.415 .000 31.17 45.63

46.800* 2.415 .000 39.57 54.03

-24.000* 2.415 .000 -31.23 -16.77

-11.800* 2.415 .001 -19.03 -4.57

26.600* 2.415 .000 19.37 33.83

35.000* 2.415 .000 27.77 42.23

-50.600* 2.415 .000 -57.83 -43.37

-38.400* 2.415 .000 -45.63 -31.17

-26.600* 2.415 .000 -33.83 -19.37

8.400* 2.415 .018 1.17 15.63

-59.000* 2.415 .000 -66.23 -51.77

-46.800* 2.415 .000 -54.03 -39.57

-35.000* 2.415 .000 -42.23 -27.77

-8.400* 2.415 .018 -15.63 -1.17

(J) Kelompok

K1

K2

K3

Gliben

K-

K2

K3

Gliben

K-

K1

K3

Gliben

K-

K1

K2

Gliben

K-

K1

K2

K3

(I) Kelompok

K-

K1

K2

K3

Gliben

Mean

Dif f erence

(I-J) Std. Error Sig. Lower Bound Upper Bound

95% Conf idence Interv al

The mean dif f erence is signif icant at the .05 lev el.*.

Homogeneous Subsets

48

GD post 4

Tukey HSDa

5 82.20

5 90.60

5 117.20

5 129.00

5 141.20

1.000 1.000 1.000 1.000 1.000

Kelompok

Gliben

K3

K2

K1

K-

Sig.

N 1 2 3 4 5

Subset f or alpha = .05

Means for groups in homogeneous subsets are displayed.

Uses Harmonic Mean Sample Size = 5.000.a.

49

Normalitas dan Homogenitas

Variabel Kelompok Shapiro-Wilk (p) Levene Test (p)

Normal K- 0,877

0,358

K1 0,300

K2 0,705

K3 0,738

Gliben 0,650

GD pre K- 0,678

0,958

K1 0,879

K2 0,705

K3 0,980

Gliben 0,987

GD post 1 K- 0,272

0,817

K1 0,087

K2 0,730

K3 0,713

Gliben 0,665

GD post 2 K- 0,618

0,609

K1 0,593

K2 0,994

K3 0,228

Gliben 0,482

GD post 3 K- 0,715

0,277

K1 0,687

K2 0,955

K3 0,254

Gliben 0,875

GD post 4 K- 0,777

0,259

K1 0,154

K2 0,899

K3 0,955

Gliben 0,867

50

Tabel Uji Multivariat tidak berpasangan One Way ANOVA

Variabel Kelompok Mean SD p

Normal K- 83 ± 9,874

0,072

K1 89,4 ± 9,154

K2 83,8 ± 6,058

K3 94,8 ± 10,474

Gliben 79,4 ± 5,771

GD pre K- 168,4 4,980

0,460

K1 164,6 5,550

K2 167,2 4,970

K3 162,8 6,648

Gliben 163 6,519

GD post 1 K- 167,4 + 4,336

< 0,001*

K1 159,6 ± 5,459

K2 154,2 ± 7,225

K3 147,6 ± 5,030

Gliben 131,6 ± 4,393

GD post 2 K- 159,4 ± 6,504

< 0,001*

K1 149,8 ± 5,891

K2 136,4 ± 3,362

K3 119,2 ± 6,229

Gliben 107,2 ± 9,203

GD post 3 K- 151,6 ± 4,159

< 0,001*

K1 139,8 ± 7,497

K2 129,2 ± 2,588

K3 113,6 ± 6,229

Gliben 101,2 ± 5,357

GD post 4 K- 141,2 ± 1,483

< 0,001*

K1 129 ± 3,536

K2 117,2 ± 2,387

K3 90,6 ± 5,177

Gliben 82,2 ± 5,070

Keterangan :

* Signifikan p < 0,05

51

Tabel Uji Post Hoc

K1 K2 K3 Gliben

GD post 1

K- 0,190 0,008* < 0,001* < 0,001*

K1 – 0,524 0,016* < 0,001*

K2 – 0,332 < 0,001*

K3 – 0,001*

GD post 2

K- 0,152 < 0,001* < 0,001* < 0,001*

K1 – 0,022* < 0,001* < 0,001*

K2 – 0,003* < 0,001*

K3 – 0,047*

GD post 3

K- 0,020* < 0,001* < 0,001* < 0,001*

K1 – 0,041* 0,002* < 0,001*

K2 – 0,002* < 0,001*

K3 – 0,013*

GD post 4

K- 0,001* < 0,001* < 0,001* < 0,001*

B1 – 0,001* < 0,001* < 0,001*

B2 – < 0,001* < 0,001*

B3 – 0,018*

Keterangan :

* Signifikan p < 0,05

52

53

54

BIODTA MAHASISWA

Identitas

Nama : Bobby Adi Chandra

NIM : G2A007048

Tempat/tanggal lahir : Semarang/16 Oktober 1989

Jenis Kelamin : Laki-laki

Alamat : Jl.Singa Tengah II no 11A, Semarang

Nomor HP : 081215151501

e-mail : bobby_adichandra89@yahoo.co.id

Riwayat Pendidikan Formal

1. SD N 04 Semarang : Lulus tahun:2001

2. SMP N 06 Semarang : Lulus tahun:2004

3. SMA N 02 Semarang : Lulus tahun:2007

4. FK UNDIP : Masuk tahun:2007