Muhammad Taha

Muhammad Taha

Institutional address: Atta-ur-Rahman Institute for Natural Product Discovery, Universiti Teknologi MARA (UiTM), Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor D. E. MalaysiaHome Address:Flat 2-10,Tanga 3 Block-Gamalia, Astana Alam-2, Puncak Alam-42300, Selangor MalaysiaCell # 0060182901765

Number of Publication: 72

Impact Factor: 107.60

Number of Citations: 490

h-index : 12

Google Scholar http://scholar.google.com.my/citations?hl=en&user=xUOt_10AAAAJ&view_op=list_works&pagesize=100

Researchgatehttp://www.researchgate.net/profile/Muhammad_Taha2

PERSONAL INFORMATION

Date of Birth : 23rd March, 1978.Marital status : MarriedNationality : PakistaniPassport No. : AA7192612 ACADEMIC

Current Position: Senior Lecturer Atta-ur-Rahman Institute for Natural Product Discovery, Universiti Teknologi MARA (UiTM), Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor D. E. Malaysia

Postdoctoral Scholar: Atta-ur-Rahman Institute for Natural Product Discovery, Universiti Teknologi MARA (UiTM), Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor D. E. Malaysia from 09-19-2011 to 19-12-2013

Ph. D. H. E. J. Research Institute of Chemistry International centre for Chemical & Biological Sciences, University of Karachi, Karachi 20, April 2011

Thesis Title: Synthetic Approaches towards Disulfides, Sulfones, Schiff Bases of Acylhydrazide and Unsymmetrical Ureas in Search of Potential Therapeutics.

1

Muhammad Taha

2008-2011 Research Fellow (Organic Chemistry) H. E. J. Research Institute of Chemistry,

International centre for Chemical & Biological Sciences, University of Karachi, Karachi

2005-2008 Junior Research Fellow (Organic Chemistry) H. E. J. Research Institute of Chemistry,

International centre for Chemical & Biological Sciences, University of Karachi, Karachi

2006- 2007 Advanced M. Phil. Courses Organic Chemistry (4 GPA/4) H. E. J. Research Institute of Chemistry, International centre for Chemical & Biological Sciences, University of Karachi, Karachi

Detail of Advanced M. Phil. Courses.S.No Course No. Title Grade

1 CHEM-701 General Spectroscopy A2 CHEM-702 Mechanism, Structure and Reactivity A3 CHEM-703 Stereochemistry A4 CHEM-704 Practical-I (This course will focus on good

Laboratory Practices and Instrumentation)A

5 CHEM-705 Biosynthesis and Isolation of Natural Productsand Bioassay Screenings

A

6 CHEM-706 Organic Synthesis A7 CHEM-707 Practical-II (This course will cover practical

Training in the field of Organic Chemistry)A

8 TM-301 Mathematics for Chemists A9 TM-302 Computer Skills A10 TM-303 Chemical Calculation / Problem Solving A11 TM-304 Introduction to Statistics A

2

Muhammad Taha

Special courses

1. X-ray crystallography, During July 8th to August 11th, 2006. Delivered by Dr. Masood Parvez University of Calgary, Alberta, Canada.

2. NMR Spectroscopy, During January 10th to 24th, 2007.Delivered by Dr. Daniel D. Traficante University of Rhode, Island, USA.

3. Mass Spectrometry, During February 7th to 29th, 2008. Delivered by Prof. Dr. David SmithUniversity of Nebraska, Lincoln, Nebraska, USA.

4. GRE (ETS) USA International Subjective (Chemistry)November 2007 Score 790, (Percentile 80)

Scholarship

Merit Scholarship from H.E.J. Research Institute of Chemistry

Academic Achievements2008-2011 Merit Double scholarship

80% percentile in GRE (Chemistry) by ETS, USA2005 Dr. Atta-ur-Rahman Gold Medal Chemistry, 1st Class 1st position MSc.2003- 2004 Master of Science

Chemistry, 1st Class 1st position (Gold medal) with 3.90/4 GPA University of Sindh, Jamshoro, Hyderabad.2000- 2003 Bachelor of Science

Chemistry, 1st Class 1st position (Gold medal) with 3.12/4 GPA University of Sindh, Jamshoro Hyderabad.

RESEARCH INTEREST

Synthesis of Bioactive Compounds Developing new methodologies in Synthetic Organic Chemistry Asymmetric Synthesis

INTERNATIONAL CONFERENSES ATTENDED

12th International Symposium on Natural Product Chemistry, 22-25th November, 2010, Karachi, Pakistan.

11th International Symposium on Natural Product Chemistry, 29th October to 1st November, 2008, Karachi, Pakistan.

10th International Symposium on Natural Product Chemistry, Karachi, 06-09th January, 2006, Karachi, Pakistan.

3

Muhammad Taha

Teaching experience

Chemistry tutor in the 1st-3rd Camp of 2th National Chemistry Talent Contest.Organized by H.E.J. Research Institute of Chemistry International Center for ChemicalSciences. University of Karachi. For 38th International Chemistry Olympiad 2006

Chemistry tutor in the 1st-3rd Camp of 3th National Chemistry Talent ContestOrganized by H.E.J. Research Institute of Chemistry International Center for ChemicalSciences University of Karachi. For 39th International Chemistry Olympiad 2007

Chemistry tutor in the 1st-3rd Camp of 4th National Chemistry Talent ContestOrganized by H.E.J. Research Institute of Chemistry International Center for ChemicalSciences. University of Karachi. For 40th International Chemistry Olympiad 2008

Chemistry tutor in the 3rd Camp of 5th National Chemistry Talent ContestOrganized by H.E.J. Research Institute of Chemistry International Center for ChemicalSciences. University of Karachi. For 41st International Chemistry Olympiad during 2009

Chemistry tutor in the 1st Camp of 6th National Chemistry Talent ContestOrganized by H.E.J. Research Institute of Chemistry International Center for ChemicalSciences. University of Karachi. For 42nd International Chemistry Olympiad-2010

A short course of fundamental of organic Chemistry for the M.S. / PhD students Organized by Atta-ur-Rahman Institute for Natural Product Discovery, Universiti Teknologi MARA (UiTM), Puncak Alam Campus, 42300 Bandar Puncak Alam, Selangor D. E. Malaysia. 6-Feb-15 March

Research Project Win

1. Dana Dana Pembudayaan Penyelidikan (RAGS) RAGS ref no.: 600-RMI/RAGS 5/3

(2/2012).

2. Dana Kecemerlangan Grant Scheme [grant No. 600-RMI/DANA 5/3 RIF (143/2012).

3. Kelulusan Skim Geran Penyelidikan Eksploratori (ERGS) FASA01/2013

4.

Supervision of 21 students as listed below

S.No Student Name Topic Remarks Degree1 Aqilah Abd

Rahman Synthesis of 4-methoxybenzoylhydrazones

and their biological activityCompleted B. Pharmacy

(Hons) 20132 Mohd Syukri

Baharudin, Synthesis of 2-methoxybenzoylhydrazones

and their biological activityCompleted B. S. (Hons)

20133 Solehah Binti

razaliSynthesis of novel Schiff bases of

benzimidazoleCompleted B. Pharmacy

(Hons)

4

Muhammad Taha

4 Wan Fazlina wati Binti Wan Ismail

Synthesis of novel Benzimidazole hydrazones

Completed B. Pharmacy (Hons)2013

5 Nor aziemah Binti Awizan

Synthesis of indole Schiff bases derivatives

Completed B. S. (Hons)2013

6 Nor Hasliza Abd. Hamid

Synthesis of indole hydrazones derivatives Completed B. S. (Hons)2013

7 Izzatul Ainaa Binti Saadun

Synthesis and Characterization of Benzimidazole compound

Completed B. S. (Hons)

8 Muhammd Helmi Bin Mohamad

Synthesis and evaluating biological potential of 4-methylBenzimidazole

derivatives.

Completed B. S. (Hons)2014

9 Amira Synthesis of quinoline hydrazones and evaluation of their biological potential

Completed B. Pharmacy (Hons)2014

10 Noor Arfiqah Ahmad

Synthesis of benzothiazole derivatives and evaluation of their biological potential

Completed B. Pharmacy (Hons)2014

11 Fatin Ummi Farhanah

Synthesis and evaluating biological potential of 4,6-DichloroBenzimidazole

derivatives.

Completed B. Pharmacy (Hons)2014

12 Noor shahida Binti Ahmad

Kamal

Synthesis and evaluating biological potential of 5-

ChloropyrideneBenzimidazole derivatives.

Completed B. Pharmacy (Hons)2014

13 Mohammad Qamarruddin

Bin Rokei

Synthesis of benzohydrazide schiff base derivatives having Oxadiazolic ring

completed B. S. (Hons)2015

14 Abdul Rahim Bin Abdul

Hamid

Synthesis of Novel derivatives of Oxadiazole

completed B. S. (Hons)2015

15 Muhammad Afifi Binti Mohd Faridz

Synthesis and Pharmacological activities of Morphine and Coumarin Derivatives

In progress M. S.

16 Mohamad Azlan Bin Mohd Shah

Synthesis of thiophene, benzofuran hydrazone and its biological activities

In progress M. S.

17 Mastura Binti Arbin

Synthesis of novel derivatives of benzothiazole and evaluation of their

anticancer potential

In progress M. S.

18 Herizal Bin Ali Nuzar

Synthesis of benzoyl, indole hydrazones and its biological activities

In progress M. S.

19 N. Khairunissa Nik Abdullah Zawawi

Synthesis of novel Benzimidazole and Biscoumarins, derivatives, and

evaluation of their biological potential

In progress Ph. D.

20 Syahrul Imran Abu Bakar

Synthesis and bioactivity of bisindole deand Flavones derivatives

In progress Ph. D.

21 Khaleed Synthesis of novel benzimidazole derivatives

In progress Ph. D.

5

Muhammad Taha

Course Coordination Responsibilities

Create and facilitate a classroom climate that is conducive to student learning and academic integrity.

Facilitate course development through reflection and student evaluations.

Supervise teaching assistants assigned to the course.

In consultation with the department head, select appropriate faculty instructors to ensure satisfactory course delivery.

Develop a meaningful and connected topic sequence and schedule in consultation with other instructors involved in the course.

Provide students with course syllabus that includes broad course objectives, course schedule, grading policy, expectations of academic integrity, policy for missed exams, etc.

Coordinate course activities including the development of innovative teaching strategies and maintain course information on the UIC Blackboard Courseinfo web site or equivalent site.

Attend, as necessary, lectures, recitations and other instructional activities of participating faculty to facilitate consistency of the course.

Assure that course content allows student achievement of objectives associated with that course.

Organize and hold meetings of the course instructors to discuss issues affecting student learning, testing and other classroom issues.

Organize and hold periodic meetings with the class representatives for the course to obtain constructive student feedback.

Evaluate student achievement.

Select test format appropriate to course objectives.

Monitor student progress.

Grade assignments, quizzes, and tests (if appropriate, e.g. multiple choice tests using STAN)

Record and assign final grades in consultation with other course faculty instructors.

Coordinate dissemination and collection of Student-Instructor Evaluations.

6

Muhammad Taha

Complete the End of Course Report and send to EPC within 4 weeks of the end of the semester.

Accountability:

Course coordinators are accountable to their department head for academic and administrative activities associated with a course.

List of Publications

1. Muhammad Taha*, Nor Hadiani Ismail, Salima Lalani, Muhammad Qaiser Fatmi,

Atia-tul-Wahab, Salman Siddiqui, Khalid Mohammed Khan, Syahrul Imran, M.I.

Choudhary. Synthesis of novel inhibitors of α-glucosidase based on the benzothiazole

skeleton containing benzohydrazide moiety and their molecular docking studies. Eur J

Med Chem.2015, 92, 387-400.

2. Muhammad Taha* Nor Hadiani Ismail, Ajmal Khan, Syed Adnan Ali Shah,

Ammarah Anwar, Sobia Ahsan Halim, M. Qaiser Fatmi, Syahrul Imran, Fazal Rahim

and Khalid Mohammed Khan. Synthesis of Novel Derivatives of Oxindole, their

Urease Inhibition and Molecular Docking Studies. Bioorg. Med Chem Lett. Accepted

2015.

3. Muhammad Taha*, Nor Hadiani Ismail, Syahrul Imran, Manikandan Selvaraj,

Hesham Rashwan, Fatin Ummi Farhanah, Fazal Rahim, Kesavanarayanan Krishnan

Selvarajane, Muhammad Ali. Synthesis of benzimidazole derivatives as potent β-

glucuronidase inhibitors, Bioorg. Chem. 2015.

4. Fazal Rahim, Khadim Ullah, Hayat Ullah, Abdul Wadood, Muhammad Taha, Ashfaq

Ur Rehman,Imad uddin, Muhammad Ashraf, Ayesha Shaukat, Wajid Rehman, Shafqat

Hussain, Khalid Mohammed Khan. Triazinoindole analogs as potent inhibitors of α-

glucosidase: Synthesis, biological evaluation and molecular docking studies. Bioorg.

Chem. 2015, 58 81–87.

5. N.K.N.Z., Abdullah, Muhammad* Taha, N. Ahmat*, A. Wadood, N.H. Ismail, F.

Rahim, M. Ali, N. Abdullah, K.M. Khan, Novel 2,5-Disubtituted-1,3,4-Oxadiazoles

with Benzimidazole Backbone: A New Class of β-Glucuronidase Inhibitors and In

Silico Studies Bioorg. Med. Chem. (2015) In press.

7

Muhammad Taha

6. Waqas Jamil, Sorath Solangi, Muhammad Ali, Khalid Muhammad Khan, Muhammad

Taha, Muhammad Yar Khuhawar. Syntheses, Characterization, In Vitro Antiglycation

and DPPH Radical Scavenging Activities of Isatin Salicylhydrazidehydrazone and its

Mn (II), Co (II), Ni (II), Cu (II), and Zn (II) Metal Complexes. Arabian Journal of

Chemistry, 2015 in press (doi:10.1016/j.arabjc.2015.02.015)

7. Muhammad Taha*, N. H. Ismail, M.S. Baharudin, S. Lalani S. Mehboob, K.M.

Khan, S. yousuf, S. Siddiqui F. Rahim M.I. Choudhary. Synthesis crystal structure of

2-methoxybenzoylhydrazones and evaluation of their a-glucosidase and urease

inhibition potential. Med. Chem. Res. 2015, 24, 1310-1324.

8. Muhammad Taha*, Nor Hadiani Ismail, Waqas Jamil, Khalid Mohammed Khan,

Uzma Salar, Syed Muhammad Kashif, Fazal Rahim, and Yawar Latif. "Synthesis and

evaluation of unsymmetrical heterocyclic thioureas as potent β-glucuronidase

inhibitors." Medicinal Chemistry Research: 1-8. 2015 in press.

9. M Ahmed Mesaik, Khalid Mohammed Khan, Fazal Rahim, Muhammad Taha, Syed

Moazzam Haider, Shahnaz Perveen, Ahmed Shukralla Khalid, Omer M Abdalla,

Samreen Soomro, Wolfgang Voelter. Synthetic indole Mannich bases: Their ability to

modulate in vitro cellular immunity. Bioorg. Chem. 2015, 60, 118-122.

10. Khalid Mohammed Khan and M. Iqbal Choudhary Fazal Rahim, Samreen,

Muhammad Taha, Syed Muhammad Saad, Shahnaz Perveen, Momin Khan,

Muhammad Tanveer Alam. Antileishmanial Activities of Benzothiazole Derivatives. J

Chem Soc. Pak. 2015, 37, 157.

11. Syed Muhammad Saad, Khalid Mohammed Khan, Shahnaz Perveen, Wolfgang

Voelter, Muhammad Taha. A new and facile CuCl2·2H2O-catalyzed one-pot three-

component synthesis for quinazolines. 2015, Monatshefte für Chemie - Chemical

Monthly in Press.

12. Khalid Mohammed Khan, Muhammad Irfan, Mahwish Ashraf, Muhammad Taha,

Syed Muhammad Saad, Shahnaz Perveen, M Iqbal Choudhary.Synthesis of phenyl

thiazole hydrazones and their activity against glycation of proteins Medicinal

Chemistry Research: 1-8. 2015 in press.

13. Fazal Rahim, Fazal Malik, Hayat Ullah, Abdul Wadood, Fahad Khan, Muhammad

Tariq Javid, Muhammad Taha, Wajid Rehman, Ashfaq Ur Rehman, Khalid

8

Muhammad Taha

Mohammed Khan. Isatin based Schiff bases as inhibitors of α-glucosidase: Synthesis,

characterization, in vitro evaluation and molecular docking studies. Bioorg. Chem.

2015, 60, 42-48.

14. Muhammad Taha*, Nor Hadiani Ismail, Waqas Jamil , Hesham Rashwan, Syed

Muhammad Kashif, Amyra Amat Sain, Mohd Ilham Adenan, El Hassane Anouar,

Muhammad Ali, Fazal Rahim, Khalid M. Khan. Synthesis of novel derivatives of 4-

methylbenzimidazole and evaluation of their biological activities. Eur J Med Chem.

2014, 84, 731-738.

15. Khalid Mohammed Khan, Salman Siddiqui, Muhammad Saleem, Muhammad Taha,

Syed Muhammad Saad, Shahnaz Perveen, M. Iqbal Choudhary. Synthesis of Triazole

Derivatives of Schiff Bases: Novel Inhibitors of Nucleotide Pyrophosphatase /

Phosphodiesterase-1. Bioorg. Med Chem. 2014, 22, 6509-6514.

16. Waqas Jamil, Shagufta Perveen, Syed Adnan Ali Shah, Muhammad Taha Nor

Hadiani Ismail Shahnaz Perveen, Nida Ambreen, Khalid M. Khan and

Muhammad. I. Choudhary. Phenoxyacetohydrazide Schiff Bases: β-Glucuronidase

Inhibitors. Molecules 2014. 19, 8788-8802.

17. K. M. Khan, F. Rahim, A. Khan, M. Shabeer, S. Hussain, W. Rehman, Muhammad

Taha, M. Khan, S. Perveen, M. I. Choudhary. Synthesis and Structure-activity

Relationship of Thiobarbituric Acid Derivatives as Potent Inhibitors of Urease. Bioorg.

Med Chem. 2014, 22, 119-4123.

18. K. M. Khan, S.M. Saad, N. N. Shaikh, S, Hussain, M. I. Fakhri, S. Perveen,

Muhammad Taha, M. I. Choudhary. Synthesis and b-glucuronidase inhibitory

activity of 2-arylquinazolin-4(3H)-ones. Bioorg. Med. Chem. 2014, 22, 3449-3454.

19. Syahrul Imran Muhammad Taha* Nor Hadiani Ismail* Khalid Mohammed Khan,

Farzana Naz, Memona Hussain and Saima Tauseef. Synthesis of Novel

Bisindolylmethane Schiff bases and Their Antibacterial Activity. Molecules 2014, 19,

11722-11740.

20. Khalid Mohammed Khan, Fazal Rahim, Syed Adnan Ali Shah, Muhammad Taha,

Nor Hadiani Ismail, Mehwish Manzoor, Ghulam Abbas Miana, Shahnaz Perveen. Bis

9

Muhammad Taha

(indolyl) methanes Synthesis Through Sodium Iodate and Sodium Hydrogen Sulfite in

Water. J Chem Soc. Pak. 2014, 36, 1158-1161.

21. Ahmad Nazif Aziz, Muhammad Taha*, Nor Hadiani Ismail, El Hassane Anouar,

Sammer Yousuf, Waqas Jamil, Khalijah Awang, Norizan Ahmat, Khalid M. Khan and

Syed Muhammad Kashif. Synthesis, Crystal Structure, DFT Studies and Evaluation of

the Antioxidant Activity of 3,4-Dimethoxybenzenamine Schiff Bases. Molecules 2014.

19, 8414-8433.

22. MuhammadTaha*, Nor Hadiani Ismail, Muhammad Ali, Khalid M. Khan, waqas

Jamil, Syed Muhammad Kashif, Mohammad Asraf. Synthesis of Indole-2-hydrazones

in Search of Potential Leishmanicidal Agents. Med. Chem. Res. 2014, 23, 5282–5293.

23. K. M. Khan, F. Rahim, A. Wadood, N. Kosar, Muhammad Taha, A. Khan, M. I.

Fakhri, M. Junaid, W.Rehman, M. Khan, S. Perveen, O. Abid, B. Mohammad, M.

Sajid, M. I. Choudhary. Synthesis and Molecular Docking Studies of Potentn α-

Glucosidase Inhibitors Based on Biscoumarin Skeleton. . Eur J Med Chem. 2014, 81,

245-252.

24. Zafar Saeed Saify, Arfa Kamil, Shamim Akhtar, Muhammad Taha, Ajmal Khan,

Khalid Mohammed Khan, Sarwat Jahan, Fazal Rahim, Shahnaz Perveen, M. Iqbal

Choudhary. 2-(2'-Pyridyl) benzimidazole Derivatives and their Urease Inhibitory

Activity. Med. Chem. Res., 2014, 23, 4447-4454.

25. Khalid M. Khan, Nida Ambreen, Muhammad Taha, Sobia A. Halim, Zaheer-ul-Haq,

Shagufta Naureen, Saima Rasheed, Shahnaz Perveen, Sajjad Ali, Mohammad Iqbal

Choudhary. Structure-Based Design, Synthesis and Biological Evaluation of ß-

Glucuronidase Inhibitors. J. Comput. Aided Mol. Des. 2014, 28, 577-585.

26. K. M. Khan, F. Rahim, A. Wadood, Muhammad Taha, M. Khan, S. Naureen, N.

Ambreen, S. Hussain, S. Perveen, M.I. Choudhary. Evaluation of Bisindole as Potent

β-Glucuronidase Inhibitors: Synthesis and In Silico Based Studies. Bioorg. Med.

Chem. Lett. 2014, 24, 1825-1829.

27. Muhammad Taha*, Nor Hadiani Ismail, Syahrul Imran, Khalid M. Khan 4-[5-(2-

Methoxyphenyl)-1,3,4-oxadiazol-2-yl]benzohydrazide. Molbank 2014, M826.

10

Muhammad Taha

28. Sadia Sultan, Muhammad Taha, Syed Adnan Ali Shah, Bohari M. Yamind, Hamizah

Mohd Zaki. (E)-3-Chloro-N-(2-fluorobenzylidene)-thiophene-2-carbohydrazide. Acta

Cryst. 2014, E751.

29. K.M. Khan, F. Naz, Muhammad Taha, A. Khan, S. Perveen, M.I. Choudhary, W.

Voelter. Synthesis and In Vitro Urease Inhibitory Activity of N,N'-Disubsituted

Thioureas. Eur J Med Chem. 2014, 74, 314-323.

30. K.M. Khan, W. Jamil, N. Ambreen, Muhammad Taha, S. Perveen, G.A Morales. An

Expeditious Synthetic Approach towards the Synthesis of Bis-Schiff Bases (Aldazines)

Using Ultrasound. Ultrasonics sonochemistry, 2014, 21, 1200-1205.

31. MuhammadTaha*, H. Naz, S. Rasheed, N.H. Ismail, A.A. Rahman, S. Yousuf, M.I.

Choudhary. Synthesis of 4-Methoxybenzoylhydrazones and Evaluation of Their

Antiglycation Activity. Molecules 2014, 19, 1286-1301.

32. Muhammad Taha, M.S. Baharudin, H. M. Zaki, B. M. Yamin, H. Naz. Crystal

structure of (E)-N′-benzylidene-2-methoxybenzohydrazide. Acta Cryst. (2014). E70,

o1071–o1072 [doi:10.1107/S1600536814019011]

33. Muhammad Taha, S.A.A. Shah, S. Sultan, N.H. Ismail S. Yousuf. 2-{[2-(2-Hydroxy-

5-methoxybenzylidene)hydrazin-1-ylidene]methyl}-4-methoxyphenol. Acta Cryst.

2014, E70, o131.

34. K.A.A. Alkadi, A. Adam, Muhammad Taha, M.H. Hasan S.A.A. Shah. Prenylated

Xanthone and Rubraxanthone with Antiplatelet Aggregation Activity in Human Whole

Blood Isolated from Garcinia griffithii. Orien. J. Chem. 2013, 29, 1291-1295.

35. K. M. Khan, M. Khan, N. Ambreen, Muhammad Taha, F. Rahim, S. Rasheed, S.

Saied, H. Shafi, S. Perveen, M. I. Choudhary Oxindole Derivatives: Synthesis and

Antiglycation Activity. Med Chem. 2013, 9, 681-688.

36. E.H. Anouar, S. Raweh , I. Bayach, Muhammad Taha, M.S. Baharudin, F.D. Meo,

M.H. Hasan, A. Adam, N.H. Ismail, J.F. Weber, P. Trouillas. Antioxidant properties

of phenolic Schiff bases: structure-activity relationship and mechanism of action. J

Comput Aided Mol Des, 2013, 27, 951-964.

37. Muhammad Taha*, N.H. Ismail, W. Jamil, S. Yousuf, F.M. Jaafar, M.I. Ali, S.M.

Kashif, E. Hussain. Synthesis, Evaluation of Antioxidant Activity and Crystal

Structure of 2,4-Dimethylbenzoylhydrazones. Molecules 2013, 18, 10912-10929.

11

Muhammad Taha

38. K.M. Khan, Muhammad Taha, F. Rahim, M.I. Fakhri, W. Jamil, M. Khan, S.

Rasheed, A. Karim, S. Perveen, M.I. choudhary. Acylhydrazide Schiff Bases:

Synthesis and Antiglycation Activity J. Pak. Chem Soc.2013, 35, 929-937.

39. K.M. Khan F. Rahim, N. Ambreen, Muhammad Taha, M. Khan, H. Jahan,

Najeebullah, A. Shaikh, S. Iqbal, S. Perveen, M.I. Choudhary. Synthesis of

Benzophenonehydrazone Schiff Bases and their in vitro Antiglycating Activities. Med.

Chem., 2013, 9, 588-595.

40. K. M. Khan, M. Khan, A. Karin, Muhammad Taha, N. Ambreen, A. Gojayev, S.

Perveen, M.I. Choudhary. Xanthine Oxidase Inhibition by 5-aryledene N,N’-

dimethylbarbituric Acid Derivatives. J. Pak. Chem Soc. 2013, 35, 495-498.

41. K.M. Khan, M. Khan, M. Saleem, Muhammad Taha, S. Perveen, M.I. Choudhary.

Benzimidazoles: A New Class of Carbonic Anhydrase Inhibitors. J. Pak. Chem Soc.

2013, 35, 901-904.

42. Muhammad Taha*, M.S. Baharudin, N.H. Ismail, K.M. Khan, F.M. Jaafar, Samreen,

S. Siddiqui, M.I. Choudhary. Synthesis of 2-Methoxybenzoylhydrazone and

Evaluation of their Antileishmanial Activity. Bioorg. Med Chem. Lett. 2013, 23, 3463-

3466.

43. Muhammad Taha, N.H. Ismail, F.M. Jaafar, A.N. Aziz, S. Yousuf. (E)-N’-(3,4-

Dihydroxybenzylidene)-2,4- dimethylbenzohy drazide monohydrate. Acta Cryst 2013,

E69, o490.

44. M. S. Baharudin, Muhammad Taha, N. H. Ismail, S. A. A. Shah, S. Yousuf. (E)-N'-

(4-Chlorobenzylidene)-2-methoxybenzohydrazide. Acta Cryst. 2013, E69, o276. 

45. Muhammad Taha, N.H. Ismail, A.N. Aziz, S.A.A. Shah, S. Yousuf 3-[2-

(Triphenylphosphanylidene)acetyl]-2H-chromen-2-one. Acta Cryst. 2013, E69, o245. 

46. Muhammad Taha, M.S. Baharudin, N.H. Ismail, S.A.A. Shah, S. Yousuf (E)-2-

Methoxy-N'-(2,4,6-trihydroxybenzylidene)benzohydrazide. Acta Cryst. 2013, E69,

o277.

47. Muhammad Taha, N.H. Ismail, F.M. Jaafar, K.M. Khan S. Yousuf. (E)-2,4-

Dimethyl-N'-(2-methylbenzylidene)benzohydrazide. Acta Cryst. 2013, E69, o400.

48. K.A.A. Alkadi, A. Adam, Muhammad Taha, M.H. Hasan, S.A.A. Shah. Antiplatelet

aggregation activity of 5-Hydroxyflavone, 2’-Hydroxyflavanone, Paeonol and

12

Muhammad Taha

bergenin isolated from stem bark of Garcinia malaccensis in human whole blood.

Orient. J. Chem. 2013, 29, 871-875.

49. S. G. Musharraf, A. Bibi, N. Shahid, M. Najam-ul-Haq, M. Khan, Muhammad Taha,

U. R. Mughal, K. M. Khan. Acylhydrazide and Isatin Schiff Bases as Alternate UV

Laser Desorption Ionization (LDI) Matrices for Low Molecular Weight (LMW)

Peptides Analysis. Am. J. Ana. Chem., 2012, 3, 779-789.

50. K.M. Khan, Zarbad Shah, V.U. Ahmad, N. Ambreen, M. Khan, Muhammad Taha, F.

Rahim, S. Noreen, S. Perveen, M.I. Choudhary, W. Voelter. 6-Nitroben-zimidazole

derivatives: Potential phosphodiesterase inhibitors:Synthesis and structure-activity

relationship. Bioorg. Med. Chem. 2012, 20, 1521-1526.

51. K.M. Khan, Muhammad. Taha, F. Rahim, W. Jamil, S. Perveen, M.I. Choudhary. An

Efficient Synthesis of Substituted Bis(indolyl)methanes by Using Sodium Bromate and

Sodium Hydrogen Sulfite in Water. J Iran Chem. Soc. 2012 9, 81-83.

52. K.M. Khan, Zarbad Shah, V.U. Ahmad, M. Khan, Muhammad Taha, S. Ali, S.

Perveen, M.I. Choudhary, W. Voelter. 2,4,6-Trichlorophenylhydrazine Schiff Bases

as DPPH Radical and Super Oxide Anion Scavengers. Med. Chem. 2012, 8, 452-461.

53. K.M. Khan, F. Rahim, N. Ambreen, M. Taha, S. Iqbal, S.M. Haider S. Perveen. An

Efficient Eco-Friendly Synthesis of Indole-Mannich Base. J. Chem. Soc. Pak. 2012,

34, 748-757.

54. K.M. Khan, Muhammad Taha, F. Naz, S. Ali, S. Perveen, M.I. Choudhary. Synthesis

of acylhydrazide schiff bases and their anti-oxidant activity. Med. Chem. 2012, 8, 705-

710.

55. Muhammad Taha, H. Naz, A.A. Rahman, N.H. Ismail, S. Yousuf (E)-4-Methoxy-

N0-[(pyridin-4-yl)methylidene] benzohydrazide monohydrate. Acta Cryst. 2012, E68,

o2778.

56. Muhammad Taha, H. Naz, A.A. Rahman, N.H. Ismail, S. Yousuf (E)-N-(3,4-

Dimethoxybenzylidene)-4-methoxybenzohydrazide Acta Cryst. 2012, E68, o2780.

57. H. Naz, Muhammad Taha, A.A. Rahman, N.H. Ismail, S. Yousuf. Methyl (E)-3,5-

dimethoxy-2-{[2-(4-methoxybenzoyl)hydrazin-1-ylidene]- methyl}benzoate. Acta

Cryst. 2012, E68, o2780.

13

Muhammad Taha

58. Muhammad Taha, H. Naz, A.A. Rahman, N.H. Ismail, Y. Sammer. (E)-4-Methoxy-

N'-(3,4,5-trihydroxybenzylidene)benzohydrazide methanolmonosolvate. Acta Cryst.

Acta Cryst. 2012. E68, o2846.

59. M.S. Baharudin, Muhammad Taha, N.H. Ismail, S.A.A. Shah, S. Yousuf. (2012). N'-

[(E)-2-Hydroxy-5-methoxybenzylidene]-2-methoxybenzohydrazide. Acta Cryst. 2012,

E68, o3255. 

60. Muhammad Taha, M.S. Baharudin, N.H. Ismail, S.A.A. Shah, S. Yousuf. N'-[(E)-

2,3-Dihydroxybenzylidene]-2-methoxybenzohydrazide. Acta Cryst. 2012, E68, o3256.

61. K.M. Khan, M. Ali, M. Khan, Muhammad Taha. NH4Cl Mediated new protocol for

the synthesis of 5-arylidene barbiturates. Lett. Org. Chem. 2011, 8, 28-32.

62. K.M. Khan, F. Rahim, S. A. Halim, Muhammad Taha, M. Khan, S. Perveen, Zaheer-

Ul-Haq, M. A. Mesaik, M.I. Choudhary. Synthesis of novel inhibitors of β-

glucuronidase based on benzothiazole skeleton and study of their binding affinity by

molecular docking. Bioorg. Med. Chem. 2011, 19, 4286-4294.

63. K.M. Khan, M. Khan, M. Ali, Muhammad Taha, A. Hameed, S. Ali, S. Perveen, M.I.

Choudhary. Synthesis and DPPH Radical Scavenging Activity of 5-Arylidene-N,N-

Dimethylbarbiturates. Med. Chem. 2011, 7, 231-236.

64. K.M. Khan, Z. Shah, V.U. Ahmad, M. Khan Muhammad Taha, F. Rahim, H. Jahun.

S. Perveen, M.I. Choudhary. Synthesis of 2 4 6-Trichlorophenyl Hydrazones and

Their Inhibatory Potenial Against Glycation. Med. Chem., 2011, 7, 572-580.

65. K.M. Khan, Muhammad Taha, F. Naz, M. Khan, F. Rahim, Samreen, S. Perveen,

M.I. Choudhary. Synthesis and in vitro Leishmanicidal Activity of Disulfide

Derivatives. Med. Chem., 2011, 7, 704-710.

66. S. Naz, J. H. Zaidi, T. Mehmood, S. Wali, M. Ali, Muhammad Taha, K.M. Khan.

Synthesis of imides and amides from diacetyl-l-tartaric acid anhydride. Lett. Org.

Chem. 2010, 7, 319-322.

67. K.M. Khan, Muhammad Taha, F. Rahim, M. Ali, W. Jamil, S. Perveen, M. I.

Choudhary. An improved method for the synthesis of disulfides by periodic acid and

sodium hydrogen sulfite in water. Lett. Org. Chem. 2010, 7, 415-419.

14

Muhammad Taha

68. K.M. Khan, Muhammad Taha, M. Ali, S. Perveen. A mild and alternative approach

towards symmetrical disulfides using H3IO5/NaHSO3 combination Lett. Org. Chem.

2009, 6, 319-320.

69. K.M. Khan, M. Khan, M. Ali, Muhammad Taha, S. Rasheed, S. Perveen and M.I.

Choudhary. Synthesis of bis-schiff bases of istain and their antiglycation activity

Bioorg. Med. Chem., 2009, 17, 7795-7801.

70. K.M. Khan, M. Ali, T. A. Farooqui, Momin Khan, Muhammad Taha. Bismuth

chloride mediated new method for the synthesis of 5-arylidene barbiturates J. Chem.

Soc. Pak. 2009, 31, 823-828.

71. K.M. Khan, M.Z. Khan, Muhammad Taha, G. M. Maharvi, Z. S. Saify, S. Parveen,

M. I. Choudhary. Leishmanicidal potential of N-substituted morpholine derivatives:

synthesis and structure-activity relationships. Nat. Prod. Res. 2009, 23,479-484.

72. K.M. Khan, M. Ali, Muhammad Taha, S. Perveen, M.I. Choudhary and W. Voelter.

An expedient and selective approach towards disulfides using sodium bromate/sodium

hydrogen sulfite reagent. Lett. Org. Chem. 2008, 5, 432-434.

15