gmp supplementary water

7/23/2019 Gmp Supplementary Water

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Project co-financed by

European Union Project co- financed

by Asean

European Committeefor Standardization

Implementing Agency

Supplementary ModuleSupplementary Module

GMP Workshop Kuala Lumpur 14-16GMP Workshop Kuala Lumpur 14-16

Prepared by :Haryanto Susilo - IndonesiaSurachai Piyayodilokchai - ThailandStephanie Wong Choong Moy - Malaysia

Approved by :Asean Cosetic !MP Tea

GMP SUPPLEMENTARY TRAININGGMP SUPPLEMENTARY TRAININGMODULEMODULE

WAT"# $%# C%SM"TICWAT"# $%# C%SM"TIC&S"'&S"'


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Implementing Agency Supplementary

Introduction

Water containants

Sources o( )aterWater treatent

Water puri*cation engineering

Water testing Inspection o( )ater treatent plants

#e(erences

C%+T"+T %$ P#"S"+TATI%+


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INTRODUCTION


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!o de"#ne the type o" $ater used as

the ma#n %omponent o" the

%osmet#% "ormula $#th the r#&ht'ual#ty $#th respe%t to the %hem#%al

and m#%ro(#olo%al %ontent to

prevent %ross %ontam#nat#on)

%,"CTI."


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/ike any starting aterial0 )ater ust/ike any starting aterial0 )ater ustcon(or to !ood Manu(acturing Practicecon(or to !ood Manu(acturing Practice

It ust be 1potable2 and inially coplyIt ust be 1potable2 and inially coply

)ith the 3uality o( the national standard o()ith the 3uality o( the national standard o(drinking-)aterdrinking-)ater Systes ust be properly aintained toSystes ust be properly aintained to

avoid containantsavoid containants Speci*cations and periodic testing isSpeci*cations and periodic testing is

re3uiredre3uired Monitoring record is neededMonitoring record is needed

,ASIC P#I+CIP/"S


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Types o( )ater used in cosetic processes are as (ollo)s:Types o( )ater used in cosetic processes are as (ollo)s:

$or product:$or product:

4545 Tap )ater con(oring to national standardTap )ater con(oring to national standard

6565 Puri*ed )ater 7Puri*ed )ater 7deionideioni8ed8ed,, reverse ososisreverse ososis9 (or9 (orcosetic productioncosetic production

$or cleaning:$or cleaning:

4545 So(tened )aterSo(tened )ater

$or rinsing: sae 3uality as (or the product$or rinsing: sae 3uality as (or the product

4545 Water (or *nal #inseWater (or *nal #inse$or sanitation:$or sanitation:

4545 SteaStea

WAT"# TP"


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WATER

CONTAMINANTS


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+o )ater is (ree (ro containants

Containant groups: Cheical copounds Physical copounds Solids !ases Micro-organiss 7algae0 proto8oa0 bacteria9

Mineral containants : Calciu and agnesiu

Iron and anganese Silicates Carbon dio;ide Hydrogen sul*de

WAT"# C%+TAMI+A+TS 749

Phosphates Copper Aluiniu Heavy etals +itrates


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WAT"# C%+TAMI+A+TS 769

Treatent depends on )ater


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T,I'IT

Turbidity ay coe (ro:

45 Silt0 clay0 and suspended aterials

65 Sall particles include BcolloidsB


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Waterhardness

classifcation

mg/L or ppmas CaCO

3

So(t -@

Moderate @4-46

Hard 464-4D

.ery hard E 4D

WAT"# HA#'+"SS


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Source o( ra) )aterSource o( ra) )ater

4545 #ain )ater#ain )ater

6565 Sur(ace or ground )aterSur(ace or ground )ater=5=5 Well or boreholeWell or borehole

>5>5 Municipal or civil F 1tapMunicipal or civil F 1tap

)ater2)ater2?5?5 Purchased in bulkPurchased in bulk

WAT"# S%C"S


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Well constructionWell construction

4545 Inspect e;posed parts o( the )ellInspect e;posed parts o( the )ell

6565 'epth o( )ell'epth o( )ell

Check:Check:

4545 +earby septic systes+earby septic systes

6565 Ha8ardous aterials usageHa8ardous aterials usage7pesticides0 (ertili8ers0 etc97pesticides0 (ertili8ers0 etc9

=5=5 11Potability2Potability2

>5>5 Well aintenanceWell aintenance

W"// WAT"#


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STORAGE

OF WATER


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4545 May be re3uired prior to pre-treatentMay be re3uired prior to pre-treatent

6565 Check aterial o( constructionCheck aterial o( construction concrete0 steel are acceptable but checkconcrete0 steel are acceptable but check

corrosioncorrosion plastics or plastic linings ay leachplastics or plastic linings ay leach

=5=5 Check coverCheck cover to keep out insects0 birds and anialsto keep out insects0 birds and anials

>5>5 Check disin(ection practicesCheck disin(ection practices

#AW WAT"# ST%#A!"S


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THE WATER TREATMENTS


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WAT"# T#"ATM"+T !&I'A+C"

The (ollo)ing should be onitored : Sources o( )ater Treatent procedures Water treatent e3uipent Monitoring records re3uired

Water treatent guidance All )ater-treatent systes should be

subGect to: planned aintenance veri*ed onitoring

Maintenance )ork should be

docuented


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45 'isin(ection 7 i5e5 chlorination 9

65 $locculationcoagulation 7i5e5 by alu9

=5 $iltration through ulti-edia *lter

7gravel-sand-carbon9 to 4 icron

>5 $iltration through *lter si8e o( 4 icron

?5 #e-disin(ection 7i5e5 chlorination toeliinate gers9

P#"-T#"ATM"+T !&I'A+C"


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Activated-Carbon 7AC9 $iltration or ,isulphite

CH/%#I+" #"M%.A/

raw water in S trap to sewer

Water iskept

ir!"atin#

to waterso$tener% DI p"ant

artrie'"ter

( )iro)eters

ati*ate&ar+on'"ter

spra, +a""

+reak tank

air+reak to

&rain

entri$!#a" p!)p

air '"ter

-oatoperate&

*a"*e san&'"ter

e.ess water re,"e&$ro) &eioniser

NOTE /

45AC reoveschlorine butbacteria can thengro)

65AC *ltration can

reove organicipurities

=5,isulphite leavessulphate residuesbut is anti-icrobial


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(r#ne and salt tank

(r#ne

*hard* $ater

#n

+eol#te $ater so"tener-e,%han&es-a and M& "or Na

dra#n

*so"t* $ater to de#on#ser(y pass valve

WAT"# S%$T"+"#


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Water treatent roo

";ternal ra) )aterstorage

WAT"# T#"ATM"+T C%MP/"


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WATER

PURIFICATION

ENGINEERING

#everse ososis syste


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To e;aine the basic technology andre3uireents (or:

45Water treatent systes65Storage re3uireents

=5Sapling and testing

>5Microbial liits0 disin(ection

%,"CTI."S


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There should be:

proper pipe slope to avoid stagnation andcan be drained easilyJ

Proper *ttings K connections that can beeasily cleaned and saniti8edJ

constructed o( suitable aterials such aspolyethylene aterial0 stainless steel0 etc5

)ater circulation

non-return valves 7+#.9

WAT"# SST"M '"SI!+


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$urther )ater treatent puri*cation stagesdo)nstrea o( the pre-treatent syste :

Pre - disin(ection - Locculation

$iltrationSo(tening colun'isin(ection'e-ioni8ation Syste#everse ososis plus deioni8ation

&. syste/ooping o( )ater

WAT"# PI$ICATI%+ STA!"S


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There should be no dead legs

Water scours deadleg

I( '6? Kdistance isgreater than

?0 )e

havea dead legthat is too

long5

Deadleg section


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=5 The )ater iscontainated as it passes

through the valve

65 In ,all valves0,acteria can gro))henthe valves are closed

45 ,utterLy valves are betterthan ,all valves

Stagnant

)aterinside valve

WAT"# SST"M '"SI!+ 769


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Cationic column Anionic column

Hygienic pump

Outlets or storage

O!one generator

"V lig#t

HCl $aOH

%luates to

neutrali!ation

plant

Air &rea' to sewer

Drain line

(rom water so(tener

Waterust bekeptcirculating

)

2

*+,

-

)

2

*+,

-

.eturn to de/ioniser

Cartridge

(ilter , 0m

Cartridge

(ilter ) 0m

'"-I%+IN"# SCH"MATIC


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'"-I%+IN"# %P"#ATI%+

0i"ter position Opene& *a"*es 1"ose& *a"*es

Services H %peration 40> 60=0?

,ack)ash 60= 40>0?

#insing 40? 60=0>

1ar+on 0i"ter 2a"*e Position


Services H %peration @0O04 A0D04404604=04>

,ack)ash A0D04 @0O04404604=04>

Cation *lter regeneration A04604=04> @0D0O04044

,ack)ash A0D04 @04404604=04>

#insing @044 A0D0O0404404604=04>

1ation 0i"ter 2a"*e Position


Services %peration 4?04D04O 4@040606406606=

,ack)ash 4@0404O 4?04D0606406606=

Anion *lter regeneration 4@06406606= 4@0404D04O

,ack)ash 4@0404O 4?0606406606=

#insing 4?06 4@0404D04O06406606=

Anion 0i"ter 2a"*e Position


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raw water

Hig# pressure

Feedwater

under

pressure

.e

1ect

wate

r

Se

m

i/pe

rmea&

le

mem&

ran

e

2e

rmeate

wate

r

drain or recycle

3ow pressure

uri(ied water

#"."#S" %SM%SIS TH"%#

#everse ososis ay beused to:

puri*ed )ater

(eeding o( distillation unitsor ultra-*ltration units

)ater (or *nal rinse


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#% SCH"MATIC 'IA!#AM

DRINE TAN3


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.ran%h

.ran%h

2nd stage &u((er tan'

Cartridge

(ilter ) 0m

Second stage .O cartridge

First stage (iltrate (eeds second stage .O

wit# e4cess &ac' to )st stage &u((er tan'

)ststage

re1ectconcentrate

Air &rea'

to sewer

Second stage re1ect water goes &ac' to (irst stage &u((er tan'

Second stage .O water

meets #armacopoeia

standards Outlets or storage

)st stage &u((er tan'

Water (rom so(tener or de/ioniser

Water returns to )st stage &u((er tan'

Hygienic pump

First stage .O cartridge

Hig# pressure

pump

6-STA!"S #% SCH"MATIC


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???????????

1 S!

2 N/

ML!M/3 -LMN

M-5N-35!5/G

L!5

7G7 P5SS5 PMP

5 n#t10 m89h

P25M23!2LN2

-4N-2N!

53!2LN2

S/S

L P 7 P

FLFL

5-:-L LN

/ra#n

/ra#n

-P !3NK

-L3NNG LN

m

1;1

- ondu% t #v # t y

M eter

Na7 05 1+orally open2 and 1norally closed2

valves

I+SP"CTI%+ 7@9


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European Committee

for StandardizationImplementing Agency Supplementary

#"$"#"+C"S

45 AS"A+ !uidelines (or Cosetic !MP 76=9

65 WH% "'M0 Suppleentary Training Modules on!ood Manu(acturing Practice0 Water (orPharaceutical &se0 Part 4060 and =5 7649

=5 WH%0 !uidelines (or drinking-)ater 3uality0 6ndedition0 volue 4 74OO=9

>5 WH%0 !uidelines (or drinking-)ater 3uality0 6ndedition0 volue 60 74OO@9

?5 WH%0 !uidelines (or drinking-)ater 3uality0 6ndedition0 .olue =J 74OO9

@5 WH%0 !uidelines (or drinking-)ater 3uality0 6ndedition0 Addendu to .olue 4 K 6 74OOD9


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