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Epic Ingredients Sdn Bhd Nutraceutical Products

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Page 1: Epic Ingredients Sdn Bhd Nutra

Epic Ingredients Sdn Bhd

Nutraceutical Products

Page 2: Epic Ingredients Sdn Bhd Nutra

Product Function ApplicationKrill Oil Improved Cognition, reduce

chronic inflammation, Joint Health , Liver Health , PMS

Softgel, Oil Capsules

Phosphotidyl Serine (PS) Improved cognition, decrease stress, reduce depression, support skin health, improve sport performance

Candy, Chocolate, beverages, yogurt,, gummies, tablets & Capsules, Milk & Protein Powders, UHT Milk and other functional food

Gastro-AD Relief Heartburn, and restore the stomach lining

Powder in sachet, tablet

Pyrroloquinoline quinone (PQQ)

Improvements in reproduction, early development growth and Immune function, Nuero-protection, cardio-protection, Anti-oxidant

Tablet

Page 3: Epic Ingredients Sdn Bhd Nutra

Xylooligosacchraides Probiotics PQQMethyl Folic Acid

Page 4: Epic Ingredients Sdn Bhd Nutra

-Krill Oil composite of omega-3 fatty acids (EPA and DHA), Phospholipids, Asthaxanthin. - Reduce the negative action of chornic inflammation, Joint Health, Improved blood lipid profile, Amelioraton of Premenstrual Syndrome (PMS) Syndrome-Improved cognition function -Improved liver health

Krill Oil

Page 5: Epic Ingredients Sdn Bhd Nutra

Topographic maps of changes in oxyhaemoglobin concentration during working memory task, Improvement shown on the brain activities after 12 weeks daily intake of krill oil and sardin oil.

Krill Oil

Sardine Oil

Evaluation of the Effects of Krill Oil on the Management of Premenstrual Syndrome and Dysmenorrhea

Page 6: Epic Ingredients Sdn Bhd Nutra

Literature Cited• Effects of krill oil containing n-3 polysaturated fatty acids in phospholipids form on human brain

function: a randomized controlled trial in healthy elderly volunteers By: Chizuru Konagai; Kenichi Yanagimoto; Kohsuke Hayamizu; Li Han; Tomoko Tsuji; and Yoshihiko Koga . Clinical Intervention in Aging 2013;8

• Evaluation of the Effects of Neptune KrillOil™ on the Management of Premenstrual Syndrome and Dysmenorrhea

– By Fotini Sampaliss, MD. PhD; Roxandra Bunea, MD; Marie France Peland, MD;Odile Kowalski MD; Natalie Duguet, MD; Sebastien Dupuis, BSc.

• Study: Evaluation of the effects of Clinical Course of Hyperlipidemia– By Ruxandra Bunea, MD; Khassan El Farrah,MD MSc; Luisa Deutsch, MD , Alternative Medicine

Review, Volume 9, Number 4, 2004 • Evaluation of the effect of Neptune Krill Oil on Chronic Inflammation and Arthritic Symptoms

– Luisa Deutsch, MD, MSc, Department of Behavioral Science and Health Research, University Health Network Toronto

Page 7: Epic Ingredients Sdn Bhd Nutra

Building blocks of body cells, it’s responsible for communication between brain cells

60% of our brain’s dry weight are lipids, and one of the main lipid group are phospholipids

Phosphotidyl-Serine (PS)

Glycerol backbone is attached to 2 Fatty acids and a Polar head group

Page 8: Epic Ingredients Sdn Bhd Nutra

Improve Cognition-Cognition difficulties: memory decline associated with aging or pathological deterioration, can be improved by supplementing from external source. - PS has beneficial affect on memory, learning and attention.- FDA Health Claim in April 2003: “ Consumption of Phosphotidylserine may reduce the risk of cognitive dysfunction in elderly.

Support Skin Health-PS influences membrane stability, cell to cell communication, signal pathways and cell repair mechanism. - Protect the skin from Photondamage: Prevents collagen loss, Reduces Epidermal Thickness, Increase skin moisture and decrease wrinkle formation.

Page 9: Epic Ingredients Sdn Bhd Nutra

Depression and Stress Reduction- PS is responsible for communication between brain cells and helps preserve optimal hormonal balance, hence it reduces depressions and stress.

Enhance Sport Performance -Studies shows that intake of PS can lead to improve recovery, Increased time to exhaustion and reduced muscle soreness that hence improve workout performance,, by regulating the exercise related hormones (cortisol and testosterone)

Page 10: Epic Ingredients Sdn Bhd Nutra

PET Scans at 3 levels of the brain of a 59-year-old woman with cognitive decline. With 500mg/day of PS intake for 3 weeks. (Klinkhammer et al, 1,197.tingoc, 1990)

Double blind, placebo-controlled study study carried out by in 1993, the effects for 57 elderly who consumed PS (300mg/day ) for 12 weeks (Gindin et al, 1993)

Page 11: Epic Ingredients Sdn Bhd Nutra

Randomized-double blind study The eye wrinkle were evaluated by dermatologist based on global photo damage score (0 none- 7 very severe). PS (300mg/day for 12 weeks) vs control.

The hairless mice were orally administrated with 50mg/kg PS , the quantification of the numbers and depths of wrinkles in gross surface area of mice dorsal skin.

Choi et al, 2013, J Korean Soc Applied Biol chem 56, 227-235

Page 12: Epic Ingredients Sdn Bhd Nutra

Time to exhaustion increase 30 %

Kingsley et al. Medicine and science in sports and exercise. 2006; 38:64-71

Improve in recovery

PS increase Testosterone, and lead to enhance in strength and muscle size, while decrease coritsol which will lead to proteolysis. Starks et al, Journal of the International Society of Sports Nutrition, 2008 (Exercise: cycle ergometer)

Page 13: Epic Ingredients Sdn Bhd Nutra

Literatures cited • FDA, Phosphotidylserine and Cognitive Dysfunction and

Dementia (Qualified Health Claim: Final Decision Letter). 2003

• Klinkhammer P, Szelies B, Heiss WD, 1990. “Effect of Phosphotidylserine on cerebral glucose metabolism in Alzheimer’s Disease. “ Dementia 1: 197-201.

• Gindin JNM, Dedar D, Walter- Ginzburg A, Naor S, Levi S. The Effect of Plant Phosphatidylserine on Age Associated Memory Impairment and Mood in the Functioning Elderly. The Geriatric Institute for Education and Research, and Department of Geriatrics, Kaplan Hospital, Rehovot, Israel. 1993.

Page 14: Epic Ingredients Sdn Bhd Nutra

• Choi, HD., Han, JJ., Yang, JH. et al. J Korean Soc Appl Biol Chem (2013) 56: 227. doi:10.1007/s13765-013-3012-

• Kingsley.M, Wadsworth D, L.P, Kilduff, J. Mceneny and D. Benton. Effects of Phosphotidylserine on Oxidative Stress following intermittent Runnng, Med Sci. Sport Exerc, Vol.37, No 8, pp1300-1306 , 2005.

• Starks, Michael A; Starks, Stacy L; Kingsley, Michael, Purpura, Martin; and Jager, Ralf. The Effects of Phosphotidylserine on endocrine response to moderate intensity exercise.

Page 15: Epic Ingredients Sdn Bhd Nutra

Gastro-AD ®Fermented by L.delbrueckii Rosell-187 strain

Inhibit the activities of Gastric juice ( protease and chlohydric acid ) which attacks the lining wall of stomach and caused heartburn

Healing of gastric mucosa, due to suppressive effects on Interleukin 8

Relive the Heart Burn by:

Nuetralizing the HCl, which can reduce the burning sensation

Page 16: Epic Ingredients Sdn Bhd Nutra

Gastroenteropathy Patients, effects of intake of Gastro AD for one month86% Reduction of Heartburn

83% Appetite Regained

60% Lessening of vomiting

58% reduction of gastric discomfort

Bogdanov Y, 1978. Pharmachim Oct,p 27-29

Hirata Y., et AL, Japanese Medicine and Pharmaceutical Science. 49 (4): 597-601

Page 17: Epic Ingredients Sdn Bhd Nutra

Literature Cited • Hirata Y., Uchida A., 2002. Clinical Effects of Gastro-AD for

Gastritis Patients. Japanese Medicine and Pharmaceutical Science. 49 (4): 597-601

• Bogdanov Y, 1978. Pharmachim Oct,p 27-29

Page 18: Epic Ingredients Sdn Bhd Nutra

Pyrroloquinoline quinone (PQQ)Was discovered in bacteria and identified as an essential redox cofactor.

Omitting PQQ from diets can lead to growth impairment, compromised immune system and abnormal reproductive function Co-factor that play

important role in cell signaling pathway

Page 19: Epic Ingredients Sdn Bhd Nutra