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DAFTAR ISI

HALAMAN JUDUL........................................................................................ i

HALAMAN PENGESAHAN.......................................................................... ii

SURAT PERNYATAAN................................................................................. iii

KATA PENGANTAR ..................................................................................... iv

DAFTAR ISI.................................................................................................... vi

DAFTAR SINGKATAN ................................................................................. ix

DAFTAR TABEL............................................................................................ x

DAFTAR GAMBAR ....................................................................................... xi

DAFTAR LAMPIRAN.................................................................................... xii

INTISARI......................................................................................................... xiii

BAB I PENDAHULUAN........................................................................... 1

1.1. Latar Belakang.......................................................................... 1

1.2. Rumusan Masalah .................................................................... 3

1.3. Tujuan Penelitian...................................................................... 4

1.3.1 Tujuan Umum............................................................... 4

1.3.2 Tujuan Khusus.............................................................. 4

1.4. Manfaat Penelitian.................................................................... 5

1.4.1 Manfaat Praktis ............................................................ 5

1.4.2 Manfaat Teoritis......................... .................................. 5

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BAB II TINJAUAN PUSTAKA……………….......................................... 6

2.1 Infeksi daerah operasi (IDO)…......................................……... 6

2.1.1. Kriteria infeksi daerah operasi (IDO) ......................... . 7

2.2 Sectio Caesarea ........................................................................ 10

2.3 Antibiotik.................................................................................. 10

2.3.1. Mekanisme kerja antibiotik…....................................... 11

2.3.2. Ampicillin sulbactam.................................................... 12

2.3.2.1. Spektrum aktivitas antibiotik……...........…… 12

2.3.2.2. Dosis dan farmakokinetik............................... 12

2.3.2.3. Penggunaan klinis........................................... 13

2.3.3. Cephalosforin generasi ketiga....................................... 14

2.3.3.1. Spektrum aktivitas antibiotik.......................... 14

2.3.3.2. Dosis dan farmakokinetik…........................... 15

2.3.3.3. Penggunaan klinis…....................................... 15

2.4 Antibiotik profilakasis .............................................................. 16

2.5 Faktor-faktor yang mempengaruhi IDO.................................... 17

2.6 Kerangka Teori ......................................................................... 20

2.7 Kerangka Konsep.................... ................................................. 20

2.8 Hipotesis…............................................................................... 21

BAB III METODE PENELITIAN… ............................................................ 22

3.1. Jenis Penelitian dan Rancangan Penelitian..........…................. 22

3.1.1. Jenis Penelitian ............................................................. 22

3.1.2. Rancangan Penelitian.................................................... 22

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3.2. Variabel dan Definisi Operasional ........................................... 22

3.2.1. Variabel…..................................................................... 22

3.2.2. Definisi Operasional ..................................................... 22

3.3. Populasi dan Sampel................................................................. 23

3.3.1. Populasi ........................................................................ 23

3.3.2. Sampel .......................................................................... 24

3.4. Instrumen Penelitian................................................................. 25

3.5. Cara Penelitian.......................................................................... 26

3.6. Tempat dan Waktu ................................................................... 26

3.6.1. Tempat Penelitian ......................................................... 26

3.6.2. Waktu Penelitian.......................................................... 26

3.7. Analisis Hasil............................................................................ 27

BAB IV HASIL PENELITIAN DAN PEMBAHASAN............................... 28

4.1. Hasil Penelitian......................................................................... 28

4.2. Pembahasan .............................................................................. 31

4.3. Keterbatasan.............................................................................. 35

BAB V SIMPULAN DAN SARAN............................................................. 36

5.1. Simpulan................................................................................... 36

5.2. Saran ......................................................................................... 36

DAFTAR PUSTAKA… .................................................................................. 38

LAMPIRAN..................................................................................................... 41